Our first practice of this concept is a biological transdermal vaccine patch. We call it T-vaccine. T-vaccine looks like a band aid. You activate it before use by simply wetting it and stick it to your arm or your chest. On the magical patch, billions of little factories start to manufacture fresh medicine for you.

Our T-vaccine consists four modules. Each of them carries a gene circuit independently. The first one expresses TD1-Antigen fusion protein, as the core of our vaccine. The second one expresses TD1-Anjuvant fusion proteins, which enhance the antigenicity. The third one is a reporter, it notifies users whether the status of vaccine patch is all right and when they can stick the patches to arms. The last module is a kill switch. We designed a reliable suicide system in bacillus subtilis for the very first time in iGEM.