Team:Paris Bettencourt

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FIGHT TUBERCULOSIS WITH MODERN WEAPONS

Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (Mtb) that affects nearly two billion people around the world. On this website we present four new ways to use the power of synthetic biology in the fight against TB.

A biosensor that detects the presence of sequence specific antibiotic resistance genes.

A safe and specific high-throughput drug screening method that targets essential mycobacterial metabolic proteins.

A phage system with low fitness cost producing sRNA, which inhibit the synthesis of antibiotic resistance proteins.

Infiltrate macrophages with an E.coli producing TDMH, an enzyme that will lyse the Mycobacteria cell wall.
Detect
Target
Infiltrate
Sabotage
Results page
TB Facts
TB in France
TB Gallery
Gender Study
Technology Transfer
Collaboration
SensiGEM

Centre for Research and Interdisciplinarity (CRI)
Faculty of Medicine Cochin Port-Royal, South wing, 2nd floor
Paris Descartes University
24, rue du Faubourg Saint Jacques
75014 Paris, France
+33 1 44 41 25 22/25
team2013@igem-paris.org
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