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Team:Freiburg/main2
From 2013.igem.org
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<img id="klammer_gross" src="https://static.igem.org/mediawiki/2013/e/e0/Freiburg_2013_main2_Rahmen_gross_links.png"> | <img id="klammer_gross" src="https://static.igem.org/mediawiki/2013/e/e0/Freiburg_2013_main2_Rahmen_gross_links.png"> | ||
| - | <p id="abstract"> Our Team developed a universal toolkit, termed uniCAS, that enables customizable gene regulation in | + | <p id="abstract"> Our Team developed a universal toolkit, <br> termed uniCAS, that enables customizable gene |
| - | + | regulation in mammalian cells. <br> Therefore, we engineered the recently discovered and highly promising CRISPR/Cas9 system. <br> | |
| - | The regulation is based on the RNA-guided Cas9 protein, which allows targeting of specific DNA sequences. <br> | + | The regulation is based on the RNA-guided Cas9 protein, <br> which allows targeting of specific DNA sequences. <br> |
Our toolkit comprises not only a standardized Cas9 protein, <br> but also different effector domains for | Our toolkit comprises not only a standardized Cas9 protein, <br> but also different effector domains for | ||
efficient gene activation or repression. </p> | efficient gene activation or repression. </p> | ||
Revision as of 15:52, 26 September 2013
Our Team developed a universal toolkit, 
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