Team:Freiburg/main2
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Our Team developed a universal toolkit, termed uniCAS, that enables customizable gene | Our Team developed a universal toolkit, termed uniCAS, that enables customizable gene |
Revision as of 17:20, 26 September 2013
![](https://static.igem.org/mediawiki/2013/2/2c/Header_igem_freiburg_13.png)
![]() Abstract Our Team developed a universal toolkit, termed uniCAS, that enables customizable gene regulation in mammalian cells. Therefore, we engineered the recently discovered and highly promising CRISPR/Cas9 system. The regulation is based on the RNA-guided Cas9 protein, which allows targeting of specific DNA sequences. Our toolkit comprises not only a standardized Cas9 protein, but also different effector domains for efficient gene activation or repression. ![]() |
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