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Team:Freiburg/main2
From 2013.igem.org
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<img id="klammer_gross" src="https://static.igem.org/mediawiki/2013/e/e0/Freiburg_2013_main2_Rahmen_gross_links.png"> | <img id="klammer_gross" src="https://static.igem.org/mediawiki/2013/e/e0/Freiburg_2013_main2_Rahmen_gross_links.png"> | ||
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| - | <p id="text_gross"> Abstract </p | + | <p id="text_gross"> Abstract </p> |
<p id="text"> | <p id="text"> | ||
Our Team developed a universal toolkit, termed uniCAS, that enables customizable gene | Our Team developed a universal toolkit, termed uniCAS, that enables customizable gene | ||
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The regulation is based on the RNA-guided Cas9 protein, which allows targeting of specific DNA sequences. | The regulation is based on the RNA-guided Cas9 protein, which allows targeting of specific DNA sequences. | ||
Our toolkit comprises not only a standardized Cas9 protein, but also different effector domains for | Our toolkit comprises not only a standardized Cas9 protein, but also different effector domains for | ||
| - | efficient gene activation or repression. </p> | + | efficient gene activation or repression. </p> </left> |
<img id="klammer_gross" src="https://static.igem.org/mediawiki/2013/8/82/Freiburg_2013_main2_Rahmen_gross_rechts.png"> | <img id="klammer_gross" src="https://static.igem.org/mediawiki/2013/8/82/Freiburg_2013_main2_Rahmen_gross_rechts.png"> | ||
</td> | </td> | ||
Revision as of 17:25, 26 September 2013
Abstract Our Team developed a universal toolkit, termed uniCAS, that enables customizable gene regulation in mammalian cells. Therefore, we engineered the recently discovered and highly promising CRISPR/Cas9 system. The regulation is based on the RNA-guided Cas9 protein, which allows targeting of specific DNA sequences. Our toolkit comprises not only a standardized Cas9 protein, but also different effector domains for efficient gene activation or repression. 
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