Team:Freiburg/main2

From 2013.igem.org

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#cas{
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#activation{
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#epigenetic{
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#klammer_klein_rechts{
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#multiple_targeting{
 
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#licht{
 
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#text_gross{
#text_gross{
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background: url(https://static.igem.org/mediawiki/2013/9/94/Freiburg_2013_main2_Cas.png);
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background-size: 250px;
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background-repeat: no-repeat;
}
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@font-face {
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<div style="min-height:800px; margin-top:230px;" >
<div style="min-height:800px; margin-top:230px;" >
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<!-- ########################################################################################
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TABLE OBEN
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######################################################################################## -->
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  <table id="table_viereck">
  <table id="table_viereck">
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<!-- ########################################################################################
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ABSTRACT
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######################################################################################## -->
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<tr>
<tr>
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<td width="450px">
<td width="450px">
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   <img id="klammer_gross_links" src="https://static.igem.org/mediawiki/2013/e/e0/Freiburg_2013_main2_Rahmen_gross_links.png">
   <img id="klammer_gross_links" src="https://static.igem.org/mediawiki/2013/e/e0/Freiburg_2013_main2_Rahmen_gross_links.png">
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  <!-- <p id="text_gross"; text-align="center"> Abstract </p> -->
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   <div id="text">  
   <div id="text">  
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<p id="text_gross"; text-align="center"> Abstract </p>
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  <p id="text_gross" align="left"> Abstract </p>
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   Our Team developed a universal toolkit,  termed uniCAS, that enables customizable gene     
   Our Team developed a universal toolkit,  termed uniCAS, that enables customizable gene     
     regulation in mammalian cells.  Therefore, we engineered the recently discovered and highly promising   
     regulation in mammalian cells.  Therefore, we engineered the recently discovered and highly promising   
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       The regulation is based on the RNA-guided Cas9 protein, which allows targeting of specific DNA sequences.  
       The regulation is based on the RNA-guided Cas9 protein, which allows targeting of specific DNA sequences.  
       Our toolkit comprises not only a standardized Cas9 protein,  but also different effector domains for  
       Our toolkit comprises not only a standardized Cas9 protein,  but also different effector domains for  
-
       efficient gene activation or repression. </div>  
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       efficient gene activation or repression.  
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  <img id="klammer_gross_rechts" src="https://static.igem.org/mediawiki/2013/8/82/Freiburg_2013_main2_Rahmen_gross_rechts.png">  
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</div>  
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  <img id="klammer_gross_rechts" src="https://static.igem.org/mediawiki/2013/8/82/Freiburg_2013_main2_Rahmen_gross_rechts.png">  
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</td>
</td>
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<!-- ########################################################################################
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PROJECT
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######################################################################################## -->
<td>
<td>
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   <img id="klammer_gross_links" src="https://static.igem.org/mediawiki/2013/e/e0/Freiburg_2013_main2_Rahmen_gross_links.png">
   <img id="klammer_gross_links" src="https://static.igem.org/mediawiki/2013/e/e0/Freiburg_2013_main2_Rahmen_gross_links.png">
    
    
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<div id="text-box2">
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  <a href="https://2013.igem.org/Team:Freiburg/Project/1">
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    <p id="text_gross" align="left"> Our Project </p>
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  </a>
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  <div>
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<div>
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<ul style="margin-left:40px;">
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<ul style="z-index:2">
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<li style="margin-top:-30px;">
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<li>
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<span> Activation </span>
<span> Activation </span>
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<img  src="https://static.igem.org/mediawiki/2013/0/03/Freiburg_2013_main2_Activation.png" style="z-index:2">
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<img  src="https://static.igem.org/mediawiki/2013/0/03/Freiburg_2013_main2_Activation.png">
</li>
</li>
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<li>
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<li style="margin-left: -40px;">
<span> Repression </span>
<span> Repression </span>
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<img  src="https://static.igem.org/mediawiki/2013/e/e7/Repression_freiburg_13.png" style="z-index:2">
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<img  src="https://static.igem.org/mediawiki/2013/e/e7/Repression_freiburg_13.png">
</li>
</li>
    
    
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<li>
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<li style="margin-bottom:-30px;">
<span> Epigenetics </span>
<span> Epigenetics </span>
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<img src="https://static.igem.org/mediawiki/2013/3/31/Freiburg_2013_main2_Epigenetic.png" style="z-index:2">
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<img src="https://static.igem.org/mediawiki/2013/3/31/Freiburg_2013_main2_Epigenetic.png">
</li>
</li>
</ul>
</ul>
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<!-- <img id="cas" src="https://static.igem.org/mediawiki/2013/9/94/Freiburg_2013_main2_Cas.png" style="z-index:1"> -->
 
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<ul style="z-index:2">
 
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<li>
 
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  <img src="https://static.igem.org/mediawiki/2013/e/ef/UniBAss_freiburg_13.png" style="z-index:2">
 
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<span> uniBAss</span>
 
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</lI>
 
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<li>
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<ul style="margin-left:130px;">
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   <img src="https://static.igem.org/mediawiki/2013/b/bb/Freiburg_2013_main2_Multiple_Targeting.png" style="z-index:2">
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<li style="margin-top: -30px;">
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   <img src="https://static.igem.org/mediawiki/2013/b/bb/Freiburg_2013_main2_Multiple_Targeting.png">
<span> Multiple targeting </span>
<span> Multiple targeting </span>
</li>
</li>
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<li>
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<li style="margin-left: 40px;">
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   <img src="https://static.igem.org/mediawiki/2013/9/9a/Freiburg_2013_main2_Licht.png" style="z-index:2">
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   <img src="https://static.igem.org/mediawiki/2013/e/ef/UniBAss_freiburg_13.png">
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<span> uniBAss</span>
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</lI>
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<li style="margin-bottom:-30px;">
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  <img src="https://static.igem.org/mediawiki/2013/9/9a/Freiburg_2013_main2_Licht.png">
<span> Light switch </span>
<span> Light switch </span>
</li>
</li>
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</ul>
</div>
</div>
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</div>
   <img id="klammer_gross_rechts" src="https://static.igem.org/mediawiki/2013/8/82/Freiburg_2013_main2_Rahmen_gross_rechts.png">
   <img id="klammer_gross_rechts" src="https://static.igem.org/mediawiki/2013/8/82/Freiburg_2013_main2_Rahmen_gross_rechts.png">
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<!-- ########################################################################################
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TABLE UNTEN
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<table id="table_viereck">
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<!-- ########################################################################################
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HIGHLIGHTS
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<tr>
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  <td width="300px">
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  <img id="klammer_klein_links" src="https://static.igem.org/mediawiki/2013/e/e0/Freiburg_2013_main2_Rahmen_gross_links.png">
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  <div id="text-box3-4">
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      <p id="text_gross" align="left"> Highlights </p>
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  <!-- Our Team developed...  -->
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  <div style="z-index:2;">
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  <img src="https://static.igem.org/mediawiki/2013/d/d6/Freiburg_2013_main2_Highlights.png" height="50" style="position:relative; top:-30px; left:50px;"> </div>
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  </div>
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  <img id="klammer_klein_rechts" src="https://static.igem.org/mediawiki/2013/8/82/Freiburg_2013_main2_Rahmen_gross_rechts.png">
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  </td>
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<!-- ########################################################################################
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TOOLKIT
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######################################################################################## -->
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  <td width="300px">
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  <img id="klammer_klein_links" src="https://static.igem.org/mediawiki/2013/e/e0/Freiburg_2013_main2_Rahmen_gross_links.png">
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  <div id="text-box3-4">
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  <a href="https://2013.igem.org/Team:Freiburg/Project/toolkit">
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      <p id="text_gross" align="left"> Toolkit </p>
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  </a>
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  Use our Toolkit to regulate your genes!
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  <!-- <img src="https://static.igem.org/mediawiki/2013/d/d9/Freiburg_2013_main2_Toolkit.png" height="80" style="position:relative; top:-100px; left:50px;"> -->
 +
  </div>
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  </div>
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  <img id="klammer_klein_rechts" src="https://static.igem.org/mediawiki/2013/8/82/Freiburg_2013_main2_Rahmen_gross_rechts.png">
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  </td>
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<!-- ########################################################################################
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HUMAN PRACTICE
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######################################################################################## -->
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  <td width="250px">
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  <img id="klammer_klein_links" src="https://static.igem.org/mediawiki/2013/e/e0/Freiburg_2013_main2_Rahmen_gross_links.png">
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  <div id="text-box5-6">
 +
  <a href="https://2013.igem.org/Team:Freiburg/HumanPractice">
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      <p id="text_gross" align="left"> HP </p>
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  </a>
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  Our Team developed... </div>
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  <img id="klammer_klein_rechts" src="https://static.igem.org/mediawiki/2013/8/82/Freiburg_2013_main2_Rahmen_gross_rechts.png">
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  </td>
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<!-- ########################################################################################
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TEAM
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######################################################################################## -->
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  <td width="250px">
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  <img id="klammer_klein_links" src="https://static.igem.org/mediawiki/2013/e/e0/Freiburg_2013_main2_Rahmen_gross_links.png">
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  <div id="text-box5-6">
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  <a href="https://2013.igem.org/Team:Freiburg/Team2">
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      <p id="text_gross" align="left"> Team </p>
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  </a>
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  Our Team developed... </div>
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  <img id="klammer_klein_rechts" src="https://static.igem.org/mediawiki/2013/8/82/Freiburg_2013_main2_Rahmen_gross_rechts.png">
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  </td>
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</tr>
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</table>

Latest revision as of 16:38, 27 September 2013


Abstract

Our Team developed a universal toolkit, termed uniCAS, that enables customizable gene regulation in mammalian cells. Therefore, we engineered the recently discovered and highly promising CRISPR/Cas9 system. The regulation is based on the RNA-guided Cas9 protein, which allows targeting of specific DNA sequences. Our toolkit comprises not only a standardized Cas9 protein, but also different effector domains for efficient gene activation or repression.

Our Project

  • Activation
  • Repression
  • Epigenetics
  • Multiple targeting
  • uniBAss
  • Light switch

Highlights

Toolkit

Use our Toolkit to regulate your genes!

HP

Our Team developed...

Team

Our Team developed...

Retrieved from "http://2013.igem.org/Team:Freiburg/main2"