Team:Paris Bettencourt
From 2013.igem.org
Using Escherichia coli as a model organism we are developing different approaches that can contribute to the eradication of tuberculosis.
A phage system that detects the presence of sequence specific antibiotic resistance genes.
A safe and specific drug screening method that targets essential mycobacterial metabolic proteins.
A phage system with low fitness cost, producing sRNA which inhibit the synthesis of antibiotic resistance proteins.
An E. coli which invade macrophages and kill mycobacteria.
DETECT
TARGET
INFILTRATE
SABOTAGE
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