Team:TU-Munich/Project/Killswitch

From 2013.igem.org

Revision as of 17:50, 4 September 2013 by Earthnut (Talk | contribs)


Red light triggered self-destruction – a new mechanism preventing uncontrolled spread of transgenic plants

Background &nbdash; Why generating a plant which kill itself under certain conditions?

Our solution – a red light-triggered autokill system

PhyB (Phytochrome B) - PIF3/PIF6 (Phytochrome Interacting Factor 3/6) interaction under red light exposition

Reconstitution of Split-TEV-Protease

Liberation of membrane-anchored nuclease and nuclear translocation

Disruption of the genetic material and programmed cell-death

Text
Text
figure



References:

http://www.ncbi.nlm.nih.gov/pubmed/6327079 Edens et al., 1984

  1. http://www.ncbi.nlm.nih.gov/pubmed/6327079 Edens et al., 1984 Edens, L., Bom, I., Ledeboer, A. M., Maat, J., Toonen, M. Y., Visser, C., and Verrips, C. T. (1984). Synthesis and processing of the plant protein thaumatin in yeast. Cell, 37(2):629–33.




Retrieved from "http://2013.igem.org/Team:TU-Munich/Project/Killswitch"