Team:Freiburg/main2

From 2013.igem.org

(Difference between revisions)
Line 60: Line 60:
}
}
-
#activation{
 
-
height:50px;
 
-
margin-top:50px;
 
-
margin-left:2px;
 
-
}
 
-
 
-
#epigenetic{
 
-
height:50px;
 
-
margin-top:60px;
 
-
margin-left:5px;
 
-
}
 
-
 
-
#multiple_targeting{
 
-
height:50px;
 
-
margin-top:70px;
 
-
margin-right:3px;
 
-
}
 
-
 
-
#licht{
 
-
height:50px;
 
-
margin-top:70px;
 
-
margin-left:1px;
 
-
}
 
#text_gross{
#text_gross{

Revision as of 15:26, 27 September 2013


Abstract

Our Team developed a universal toolkit, termed uniCAS, that enables customizable gene regulation in mammalian cells. Therefore, we engineered the recently discovered and highly promising CRISPR/Cas9 system. The regulation is based on the RNA-guided Cas9 protein, which allows targeting of specific DNA sequences. Our toolkit comprises not only a standardized Cas9 protein, but also different effector domains for efficient gene activation or repression.

Our Project

  • Activation
  • Repression
  • Epigenetics
  • uniBAss
  • Multiple
    targeting
  • Light switch

Highlights

Toolkit

Use our Toolkit to regulate your genes!

HP

Our Team developed...

Team

Our Team developed...