Team:Freiburg/main2

From 2013.igem.org

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background: url(https://static.igem.org/mediawiki/2013/9/94/Freiburg_2013_main2_Cas.png);
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   <div>
   <div>
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<div style="z-index:2;">
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<ul style="margin-left:40px;">
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<ul>
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<li>
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<li style="margin-top:-30px;">
<span> Activation </span>
<span> Activation </span>
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<img  src="https://static.igem.org/mediawiki/2013/0/03/Freiburg_2013_main2_Activation.png" >
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<img  src="https://static.igem.org/mediawiki/2013/0/03/Freiburg_2013_main2_Activation.png">
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</li>
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<li>
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<li style="margin-left: -40px;">
<span> Repression </span>
<span> Repression </span>
<img  src="https://static.igem.org/mediawiki/2013/e/e7/Repression_freiburg_13.png">
<img  src="https://static.igem.org/mediawiki/2013/e/e7/Repression_freiburg_13.png">
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<span> Epigenetics </span>
<span> Epigenetics </span>
<img src="https://static.igem.org/mediawiki/2013/3/31/Freiburg_2013_main2_Epigenetic.png">
<img src="https://static.igem.org/mediawiki/2013/3/31/Freiburg_2013_main2_Epigenetic.png">
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<div style="z-index:2;">
 
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<ul>
 
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<li>
 
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  <img src="https://static.igem.org/mediawiki/2013/e/ef/UniBAss_freiburg_13.png">
 
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<span> uniBAss</span>
 
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</lI>
 
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   <img src="https://static.igem.org/mediawiki/2013/b/bb/Freiburg_2013_main2_Multiple_Targeting.png">
   <img src="https://static.igem.org/mediawiki/2013/b/bb/Freiburg_2013_main2_Multiple_Targeting.png">
<span> Multiple targeting </span>
<span> Multiple targeting </span>
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<li style="margin-left: 40px;">
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  <img src="https://static.igem.org/mediawiki/2013/e/ef/UniBAss_freiburg_13.png">
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<span> uniBAss</span>
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</lI>
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<li style="margin-bottom:-30px;">
   <img src="https://static.igem.org/mediawiki/2013/9/9a/Freiburg_2013_main2_Licht.png">
   <img src="https://static.igem.org/mediawiki/2013/9/9a/Freiburg_2013_main2_Licht.png">
<span> Light switch </span>
<span> Light switch </span>
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Latest revision as of 16:38, 27 September 2013


Abstract

Our Team developed a universal toolkit, termed uniCAS, that enables customizable gene regulation in mammalian cells. Therefore, we engineered the recently discovered and highly promising CRISPR/Cas9 system. The regulation is based on the RNA-guided Cas9 protein, which allows targeting of specific DNA sequences. Our toolkit comprises not only a standardized Cas9 protein, but also different effector domains for efficient gene activation or repression.

Our Project

  • Activation
  • Repression
  • Epigenetics
  • Multiple targeting
  • uniBAss
  • Light switch

Highlights

Toolkit

Use our Toolkit to regulate your genes!

HP

Our Team developed...

Team

Our Team developed...