Team:Freiburg/main2

From 2013.igem.org

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<span> Repression </span>
<span> Repression </span>
<img  src="https://static.igem.org/mediawiki/2013/e/e7/Repression_freiburg_13.png">
<img  src="https://static.igem.org/mediawiki/2013/e/e7/Repression_freiburg_13.png">
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<!--
 
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  <img src="https://static.igem.org/mediawiki/2013/e/ef/UniBAss_freiburg_13.png">
 
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<span> uniBAss</span>
 
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   <img src="https://static.igem.org/mediawiki/2013/b/bb/Freiburg_2013_main2_Multiple_Targeting.png">
   <img src="https://static.igem.org/mediawiki/2013/b/bb/Freiburg_2013_main2_Multiple_Targeting.png">
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<span style="margin-top:-5px;"> Multiple <br> targeting </span>
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<span> Multiple targeting </span>
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  <img src="https://static.igem.org/mediawiki/2013/e/ef/UniBAss_freiburg_13.png">
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<span> uniBAss</span>
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Latest revision as of 16:38, 27 September 2013


Abstract

Our Team developed a universal toolkit, termed uniCAS, that enables customizable gene regulation in mammalian cells. Therefore, we engineered the recently discovered and highly promising CRISPR/Cas9 system. The regulation is based on the RNA-guided Cas9 protein, which allows targeting of specific DNA sequences. Our toolkit comprises not only a standardized Cas9 protein, but also different effector domains for efficient gene activation or repression.

Our Project

  • Activation
  • Repression
  • Epigenetics
  • Multiple targeting
  • uniBAss
  • Light switch

Highlights

Toolkit

Use our Toolkit to regulate your genes!

HP

Our Team developed...

Team

Our Team developed...