Team:Paris Bettencourt

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     <div class="cont"><p style="  font-size:30px;line-height:32px;">FIGHT TUBERCULOSIS WITH MODERN WEAPONS </p></div>
     <div class="cont"><p style="  font-size:30px;line-height:32px;">FIGHT TUBERCULOSIS WITH MODERN WEAPONS </p></div>
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<p>An <i>E. coli</i> which invades macrophages and kills mycobacteria.</p>
<p>An <i>E. coli</i> which invades macrophages and kills mycobacteria.</p>
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Revision as of 22:19, 22 September 2013

FIGHT TUBERCULOSIS WITH MODERN WEAPONS

Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis affecting millions of people over the world. Using Escherichia coli as a model organism we are developing different approaches that could contribute to the fight against TB.

A biosensor that detects the presence of sequence specific antibiotic resistance genes.

A safe and specific high-throughput drug screening method that targets essential mycobacterial metabolic proteins.

A phage system with low fitness cost producing sRNA, which inhibit the synthesis of antibiotic resistance proteins.

An E. coli which invades macrophages and kills mycobacteria.


Detect

Target

Infiltrate

Sabotage
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Centre for Research and Interdisciplinarity (CRI)
Faculty of Medicine Cochin Port-Royal, South wing, 2nd floor
Paris Descartes University
24, rue du Faubourg Saint Jacques
75014 Paris, France
+33 1 44 41 25 22/25
team2013@igem-paris.org
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