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Team:TU-Delft/Modeling
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| + | <p align="justify">Modeling will play an important role in the iGEM project. Our total system is rather complex and requires careful tuning in order for it to work. This tuning cannot be done in the lab due to time constraints, so the modeling will be used to derive conditions on strengths of promoters and binding sites in order for the system to work. This way the correct implementation can be done in the lab, saving effort and time. | ||
| + | The modeling will first focus on the timer, then the SUMO fusion and finally the kill switch. These parts will be introduced below and details on these parts will be added later on in the project. | ||
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| + | <b>Timer</b> | ||
| + | <p align="justify" margin: 20px >Several newly discovered strains of MRSA show antibiotic resistance even to vancomycin and teicoplanin. These new evolutions of the MRSA bacterium are called Vancomycin intermediate-resistant Staphylococcus aureus (VISA). There have been claims that bacteriophage can be used to cure MRSA. | ||
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Revision as of 20:03, 16 June 2013
Modeling will play an important role in the iGEM project. Our total system is rather complex and requires careful tuning in order for it to work. This tuning cannot be done in the lab due to time constraints, so the modeling will be used to derive conditions on strengths of promoters and binding sites in order for the system to work. This way the correct implementation can be done in the lab, saving effort and time. The modeling will first focus on the timer, then the SUMO fusion and finally the kill switch. These parts will be introduced below and details on these parts will be added later on in the project.
Timer
Several newly discovered strains of MRSA show antibiotic resistance even to vancomycin and teicoplanin. These new evolutions of the MRSA bacterium are called Vancomycin intermediate-resistant Staphylococcus aureus (VISA). There have been claims that bacteriophage can be used to cure MRSA.
