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Http://2013.igem.org/Team:TU-Delft/LabWork/General Concepts
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Our project deals with <i>E.coli</i> cells which sense Auto-inducing peptides (AIPs) from the <i>Staphylococcus aureus</i> and starts producing Antimicrobial peptides in order to kill the <i>Staphylococcus aureus</i>. | Our project deals with <i>E.coli</i> cells which sense Auto-inducing peptides (AIPs) from the <i>Staphylococcus aureus</i> and starts producing Antimicrobial peptides in order to kill the <i>Staphylococcus aureus</i>. | ||
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| + | Autoinducing peptides are involved in inter-cellular communication in gram-positive bacteria. Many of these peptides are exported by dedicated systems, post translationally modified in various ways, and finally sensed by other cells via membrane-located receptors that are part of two-component regulatory systems. Autoinducing peptide-based quorum sensing systems are displayed by various gram-positive bacteria like <i>Staphylococcus aureus </i>. | ||
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Revision as of 13:53, 13 July 2013
General Concepts
Our project deals with E.coli cells which sense Auto-inducing peptides (AIPs) from the Staphylococcus aureus and starts producing Antimicrobial peptides in order to kill the Staphylococcus aureus. Autoinducing peptides are involved in inter-cellular communication in gram-positive bacteria. Many of these peptides are exported by dedicated systems, post translationally modified in various ways, and finally sensed by other cells via membrane-located receptors that are part of two-component regulatory systems. Autoinducing peptide-based quorum sensing systems are displayed by various gram-positive bacteria like Staphylococcus aureus .
