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Team:HZAU-China
From 2013.igem.org
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| - | <p style="font-family:times new roman;">Our idea comes from <i>Yersinia pestis</i> and fleas. We make use of fleas as our moving injector. When fleas feed on blood from dogs, our vaccine vector <i>Bacillus subtilis</i> will be regurgitated into blood and successfully transferred to mammalian host. <i>Bacillus subtilis</i> can express antigens which can stimulate the immunity of dogs. Meanwhile, endogenous or exogenous expression of "Antimicrobial Peptides" by <i>B. subtilis</i> can kill Yersinia pestis in fleas. In this way we achieved a safe moving vaccine factory.</p> | + | <p style="font-family:times new roman;">Our idea comes from <i>Yersinia pestis</i> and fleas. We make use of fleas as our moving injector. When fleas feed on blood from dogs, our vaccine vector <i>Bacillus subtilis</i> will be regurgitated into blood and successfully transferred to mammalian host. <i>Bacillus subtilis</i> can express antigens which can stimulate the immunity of dogs. Meanwhile, endogenous or exogenous expression of "Antimicrobial Peptides" by <i>B. subtilis</i> can kill <i>Yersinia pestis</i> in fleas. In this way we achieved a safe moving vaccine factory.</p> |
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Latest revision as of 11:22, 9 November 2013
PROJECT: Safe Moving Vaccine Factory
ABSTRACT
Our idea comes from Yersinia pestis and fleas. We make use of fleas as our moving injector. When fleas feed on blood from dogs, our vaccine vector Bacillus subtilis will be regurgitated into blood and successfully transferred to mammalian host. Bacillus subtilis can express antigens which can stimulate the immunity of dogs. Meanwhile, endogenous or exogenous expression of "Antimicrobial Peptides" by B. subtilis can kill Yersinia pestis in fleas. In this way we achieved a safe moving vaccine factory.
