Team:UC Davis

From 2013.igem.org

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                     <a href="https://2013.igem.org/Team:UC_Davis/Project_Overview"><h3>Project Background</h3></a>
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                     <a href="https://2013.igem.org/Team:UC_Davis/Project_Overview"><h3>Project Overview</h3></a>
                     <p>Learn about how we combine riboswitches and TALs into robust orthogonal mechanisms for    inducible repression.  
                     <p>Learn about how we combine riboswitches and TALs into robust orthogonal mechanisms for    inducible repression.  
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               <a href="https://2013.igem.org/Team:UC_Davis/Data"><h3>Results</h3></a>
               <a href="https://2013.igem.org/Team:UC_Davis/Data"><h3>Results</h3></a>
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                     <p>Check out the cool results of our experiments with RiboTALs.  
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                     <p>Check out the cool results of our experiments with RiboTALs. <br />
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                            <a href="https://2013.igem.org/Team:UC_Davis/AndersonPromoters"><img src="https://static.igem.org/mediawiki/2012/e/ee/Svn12_hp_new.png" class="checkmark"></a><p>We also made the Anderson promoter family controllable through induction with RiboTALs.</p>
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Welcome to the 2013 UC Davis iGEM Wiki!<br></br>We have a created a novel class of transcription factors known as RiboTALs. We sought to address the constraints placed on circuit design by the limited number of well characterized promoters at our disposal, and their respective transcription factors. Our device generates Transcriptional Activator-Like (TAL) effectors which can be engineered to bind to and repress any sequence of interest. The production of these repressor proteins is controlled by riboswitches, and thus inherit the potential of riboswitches to respond to any inducer molecule due to their engineerable and modular aptamer binding domains. <br></br> We also created a Biobrick Characterization Data Depot (The Depot) for more thorough characterization of the Registry's Biobricks. We hope that future iGEM teams may use this database to better understand a Biobrick's functionality.</p>
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Welcome to the 2013 UC Davis iGEM Wiki!<br></br>We have created a novel class of transcription factors known as RiboTALs. We sought to address the constraints placed on circuit design by the limited number of well characterized promoters at our disposal, and their respective transcription factors. Our device is a hybrid system composed of two parts: Transcriptional Activator-Like (TAL) effectors which can be engineered to bind to and repress any sequence of interest and riboswitches that can respond to any inducer molecule due to their engineerable and modular aptamer binding domains. <br></br> We also designed and implemented a Biobrick characterization database called The Depot to promote sharing and openness in iGEM.</p>
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Latest revision as of 22:43, 5 December 2013

Our Sponsors

Project Overview

Learn about how we combine riboswitches and TALs into robust orthogonal mechanisms for inducible repression.

Results

Check out the cool results of our experiments with RiboTALs.

We also made the Anderson promoter family controllable through induction with RiboTALs.

Human Practices

Take a look at how we promote sharing in iGEM through The Depot, an open BioBrick characterization database.
Visit the Depot!

Judging Criteria

Here's the criteria that we met for this year's team.

Welcome

Welcome to the 2013 UC Davis iGEM Wiki!

We have created a novel class of transcription factors known as RiboTALs. We sought to address the constraints placed on circuit design by the limited number of well characterized promoters at our disposal, and their respective transcription factors. Our device is a hybrid system composed of two parts: Transcriptional Activator-Like (TAL) effectors which can be engineered to bind to and repress any sequence of interest and riboswitches that can respond to any inducer molecule due to their engineerable and modular aptamer binding domains.

We also designed and implemented a Biobrick characterization database called The Depot to promote sharing and openness in iGEM.

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