Team:Freiburg

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Revision as of 23:50, 9 April 2014


Abstract
Our Team developed a universal toolkit, termed uniCAS, that enables customizable gene regulation in mammalian cells. Therefore, we engineered the recently understood and highly promising CRISPR/Cas9 system.
The regulation is based on the RNA-guided dCas9 protein, which allows specific targeting of DNA sequences. Our toolkit comprises not only a standardized dCas9 protein, but also different effector domains for efficient gene activation or repression.
Our Project
Highlights

All about our
project in one
slide show!

Manual
Use our Toolkit
to regulate your
genes!
Human

Practice
News

Have a look at our achievements in Lyon & Boston!

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