"
Team:Freiburg
From 2013.igem.org
| Line 1: | Line 1: | ||
{{:Template:Freiburg2013_Template1}} | {{:Template:Freiburg2013_Template1}} | ||
| - | |||
{{:Template:Freiburg2013_jquery_css}} | {{:Template:Freiburg2013_jquery_css}} | ||
| + | {{:Template:Freiburg2013_jquery}} | ||
<html> | <html> | ||
<head> | <head> | ||
| + | <script type="text/javascript" src="https://ajax.googleapis.com/ajax/libs/jquery/1.8.2/jquery.min.js"></script> | ||
| + | |||
| + | |||
| + | <script type="text/javascript"> | ||
| + | $(document).ready(function(){ | ||
| + | $('.bxslider').bxSlider({ | ||
| + | auto: true, | ||
| + | autoStart: true, | ||
| + | autoControls: true, | ||
| + | autoHover: true, | ||
| + | speed: 800, | ||
| + | pause: 7000, | ||
| + | minSlides: 2, | ||
| + | maxSlides: 2, | ||
| + | slideWidth: 360, | ||
| + | slideMargin: 10, | ||
| + | buildPager: function(slideIndex){ | ||
| + | switch(slideIndex){ | ||
| + | case 0: | ||
| + | return '<img src="gluehbirne.jpg">'; | ||
| + | case 1: | ||
| + | return '<img src="Estrane.png">'; | ||
| + | case 2: | ||
| + | return '<img src=".jpg">'; | ||
| + | case 3: | ||
| + | return '<img src=".jpg">'; | ||
| + | } | ||
| + | } | ||
| + | }); | ||
| + | }); | ||
| + | </script> | ||
| + | <style type="text/css"> | ||
| + | .bx-wrapper .bx-pager { | ||
| + | bottom: -70px; | ||
| + | } | ||
| + | |||
| + | .bx-wrapper .bx-pager a { | ||
| + | border: solid #ccc 1px; | ||
| + | display: block; | ||
| + | margin: 0 5px; | ||
| + | padding: 3px; | ||
| + | width:50px; | ||
| + | } | ||
| + | |||
| + | .bx-wrapper .bx-pager a:hover, | ||
| + | .bx-wrapper .bx-pager a.active { | ||
| + | border: solid black 3px; | ||
| + | } | ||
| + | |||
| + | .bx-wrapper { | ||
| + | margin-bottom: 120px; | ||
| + | } | ||
| + | |||
| + | |||
| + | </style> | ||
| Line 83: | Line 138: | ||
<body> | <body> | ||
| + | <ul class="bxslider"> | ||
| + | <li><img src="P1050709.jpg" /></li> | ||
| + | <li> Text </li> | ||
| + | <li><img src="P1050710.jpg" /></li> | ||
| + | <li> Text </li> | ||
| + | <li><img src="P1050711.jpg" /></li> | ||
| + | <li> Text </li> | ||
| + | <li><img src="P1050712.jpg" /></li> | ||
| + | <li> Text </li> | ||
| + | </ul> | ||
| + | |||
<div id="text"> | <div id="text"> | ||
Revision as of 14:17, 27 August 2013
- Text
- Text
- Text
- Text
Gene Regulation – Multiple Targets – Activation – Optogenetics – Repression – Inducibility – Epigenetics
Just imagine there was a tool that combined all these aspects of lab work. A tool, that was able to rule several genes at once; a tool that allowed highly specific gene modulation via stimulus induction; a tool that would be a new approach to gene regulation.
This year’s Freiburg iGEM Team uses the prokaryotic CRISPR/Cas system to enable multiple endogenous gene regulation with minimal effort. The regulation is based on a protein-RNA-DNA interaction. Customizable RNAs function as a guide for our protein in order to target specific DNA sequences. By fusing effector domains to this protein, we aim at developing a tool for multiple and inducible gene activation and repression. Despite the system's prokaryotic origin, gene target sequences are adjustable for various organisms, offering a broad application variety of our tool. Due to its great potential, the CRISPR/Cas system has become of increasing importance in current research and can be implemented in a number of novel and interesting applications, such as gene therapy or tissue engineering.
