Team:UC Davis

From 2013.igem.org

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<h1>Welcome</h1>
 
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<p><img src="https://static.igem.org/mediawiki/2013/2/2a/IGEM_2013_Group_Photo.png" width="200" height="300" align="left"></a>Welcome to the 2013 UC Davis iGEM Wiki!<br></br>Over the summer, we created a novel class of transcription factors know as RiboTALs. They can be easily engineered to bind to any sequence of interest. By controlling RiboTALs' induction through riboswitches, we have demonstrated their ability to be regulated at the translational level. Also, by switching out the type of riboswitch, there is potential for the use of different inducers.<br></br> We also created a Biobrick Characterization Data Depot for more thorough characterization of the Registry's Biobricks. We hope that future iGEM teams may use this database to better understand a Biobrick's functionality.</p>
 
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                     <a href="https://2013.igem.org/Team:UC_Davis/Project"><img src="https://static.igem.org/mediawiki/2013/9/92/RiboTal.png"></a>
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                     <a href="https://2013.igem.org/Team:UC_Davis/Project"><h3>Project Background</h3></a>
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                     <div><a href="https://2013.igem.org/Team:UC_Davis/Project_Overview">
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                     <a href="https://2013.igem.org/Team:UC_Davis/Project_Overview"><h3>Project Overview</h3></a>
                     <p>Learn about how we combine riboswitches and TALs into robust orthogonal mechanisms for    inducible repression.  
                     <p>Learn about how we combine riboswitches and TALs into robust orthogonal mechanisms for    inducible repression.  
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               <a href="https://2013.igem.org/Team:UC_Davis/Data"><img src="http://gardendoctor.files.wordpress.com/2010/05/dna_strand_2_thumb.jpg"></a>
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               <a href="https://2013.igem.org/Team:UC_Davis/Data"><img src="https://static.igem.org/mediawiki/2013/d/d5/Resultsicon_UCDavis.jpg" class="blur"></a>
               <a href="https://2013.igem.org/Team:UC_Davis/Data"><h3>Results</h3></a>
               <a href="https://2013.igem.org/Team:UC_Davis/Data"><h3>Results</h3></a>
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                     <p>Check out the results of our experiments.  
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                     <p>Check out the cool results of our experiments with RiboTALs. <br />
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                            <a href="https://2013.igem.org/Team:UC_Davis/AndersonPromoters"><img src="https://static.igem.org/mediawiki/2012/e/ee/Svn12_hp_new.png" class="checkmark"></a><p>We also made the Anderson promoter family controllable through induction with RiboTALs.</p>
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                     <a href="https://2013.igem.org/Team:UC_Davis/HumanPracticesOverview"><img src="https://static.igem.org/mediawiki/igem.org/0/00/UCD_Outreach_2013.png"></a>
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                     <a href="https://2013.igem.org/Team:UC_Davis/HumanPracticesOverview"><h3>Human Practices</h3></a>
                     <a href="https://2013.igem.org/Team:UC_Davis/HumanPracticesOverview"><h3>Human Practices</h3></a>
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                     <p>Take a look at how we designed a new database for better raw data characterization of Biobricks.  
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                     <p>Take a look at how we promote sharing in iGEM through The Depot, an open BioBrick characterization database.<br />
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                        <a href="http://dilbert.cs.ucdavis.edu/Depot" class="bold">Visit the Depot!</a>
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               <a href="https://2013.igem.org/Team:UC_Davis/Criteria"><img src="http://icons.mysitemyway.com/wp-content/gallery/glossy-black-icons-symbols-shapes/thumbs/thumbs_018666-glossy-black-icon-symbols-shapes-check-in-box.png "></a>
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               <a href="https://2013.igem.org/Team:UC_Davis/Criteria"><img src="https://static.igem.org/mediawiki/2013/f/f3/Judgingbutton_UCDavis.jpg" class="blur"</a>
               <a href="https://2013.igem.org/Team:UC_Davis/Criteria"><h3>Judging Criteria</h3></a>
               <a href="https://2013.igem.org/Team:UC_Davis/Criteria"><h3>Judging Criteria</h3></a>
                     <p>Here's the criteria that we met for this year's team.  
                     <p>Here's the criteria that we met for this year's team.  
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Welcome to the 2013 UC Davis iGEM Wiki!<br></br>We have created a novel class of transcription factors known as RiboTALs. We sought to address the constraints placed on circuit design by the limited number of well characterized promoters at our disposal, and their respective transcription factors. Our device is a hybrid system composed of two parts: Transcriptional Activator-Like (TAL) effectors which can be engineered to bind to and repress any sequence of interest and riboswitches that can respond to any inducer molecule due to their engineerable and modular aptamer binding domains. <br></br> We also designed and implemented a Biobrick characterization database called The Depot to promote sharing and openness in iGEM.</p>
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Latest revision as of 22:43, 5 December 2013

Our Sponsors

Project Overview

Learn about how we combine riboswitches and TALs into robust orthogonal mechanisms for inducible repression.

Results

Check out the cool results of our experiments with RiboTALs.

We also made the Anderson promoter family controllable through induction with RiboTALs.

Human Practices

Take a look at how we promote sharing in iGEM through The Depot, an open BioBrick characterization database.
Visit the Depot!

Judging Criteria

Here's the criteria that we met for this year's team.

Welcome

Welcome to the 2013 UC Davis iGEM Wiki!

We have created a novel class of transcription factors known as RiboTALs. We sought to address the constraints placed on circuit design by the limited number of well characterized promoters at our disposal, and their respective transcription factors. Our device is a hybrid system composed of two parts: Transcriptional Activator-Like (TAL) effectors which can be engineered to bind to and repress any sequence of interest and riboswitches that can respond to any inducer molecule due to their engineerable and modular aptamer binding domains.

We also designed and implemented a Biobrick characterization database called The Depot to promote sharing and openness in iGEM.

Retrieved from "http://2013.igem.org/Team:UC_Davis"