Team:SCAU-China

From 2013.igem.org

(Difference between revisions)

Latest revision as of 22:21, 27 September 2013

Overview

Organophosphorus (OP) compounds, which are highly toxic contaminants in agro-environment and food security, have been widely applied to pesticides. Parathion is a typical representative of organophosphorus pesticides. Residues of OP pesticides in food are also often reported.So, this year, our goal is to construct a system that can sense and degrade OP pesticides.

View Our Work →

Our Project

OP Degradation

The bacterial organophosphorus hydrolase enzyme hydrolyzes and detoxifies a broad range of toxic organophosphate pesticides. In the first part, we need to use these enzymes to degrade parathion into PNP.
PNP Sensor

The second part is a biosensor of the hydrolysis product P-Nitrophenol (PNP). There is no operon that can react to parathion. We foucus on constructing a PNP sensor, which can reflect the existence of parathion.
PNP Degradation

We also design a PNP degradation system. We use enzymes NphA1 and NphA2 to degrade PNP, but fail. We find another pathway to degrade PNP in 5 steps with 4 enzymes in Rhodococcus sp. Strain PN1.
Suicide System

With the public increasingly concerned about biosafety, we conceived a suicide gene circuit to ensure these recombinanational bacteria can only survive in laboratories and not cause horizontal gene transfer.

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           <li><a href="#">Results</a>
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-            <li><a href="https://2013.igem.org/Team:SCAU-China/Modeling" >Modeling</a></li>
              <li><a href="https://2013.igem.org/Team:SCAU-China/Parts" >Biobricks</a></li>
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            <h2>Overview</h2>
-           <p>&nbsp;&nbsp;&nbsp;&nbsp;Organophosphorus pesticides (OP), which are highly toxic, are still used in some developing countries. Many terrestrial and aquatic ecosystems across the world are contaminated with OP. Residues of OP in food are also often reported</p>
+           <p>&nbsp;&nbsp;&nbsp;&nbsp;Organophosphorus (OP) compounds, which are highly toxic contaminants in agro-environment and food security, have been widely applied to pesticides. Parathion is a typical representative of organophosphorus pesticides. Residues of OP pesticides in food are also often reported.So, this year, our goal is to construct a system that can sense and degrade OP pesticides.</p>
-          <p>&nbsp;&nbsp;&nbsp;&nbsp;This year, our goal is to construct a system that can sensing and degrade organophosphorus pesticides.</p>
+           <p><a href="https://2013.igem.org/Team:SCAU-China/Project">View Our Work &rarr;</a></p>
-           <p><a href="#">View Our Work &rarr;</a></p>
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-     <p><a href="http://www.scau.edu.cn"><img src="https://static.igem.org/mediawiki/2013/d/d3/Scau_sclo.png" alt="" width="396" height="111"></a>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<a href="http://life.scau.edu.cn"><img src="https://static.igem.org/mediawiki/2013/f/fa/Scau_lifelogo.png" alt="" width="453" height="116"></a></p>
+     <div id=sponsor1><a href="http://www.scau.edu.cn"><img src="https://static.igem.org/mediawiki/2013/d/d3/Scau_sclo.png" alt="" width="411" height="116"></a></div> <div id=sponsor2><a href="http://life.scau.edu.cn"><img src="https://static.igem.org/mediawiki/2013/f/fa/Scau_lifelogo.png" alt="" width="411" height="116"></a></div>
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-         <li><a href="https://2013.igem.org/Team:SCAU-China/Team" >About Us</a></li>
+         <li>If you can't browse, please use Chrome or Firefox.</li>
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Team:SCAU-China

From 2013.igem.org

Latest revision as of 22:21, 27 September 2013

Overview

Our Project

OP Degradation

PNP Sensor

PNP Degradation

Suicide System