Team:Freiburg/main2
From 2013.igem.org
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+ | background: url(https://static.igem.org/mediawiki/2013/9/94/Freiburg_2013_main2_Cas.png); | ||
+ | background-size: 250px; | ||
+ | background-position:120px 150px; | ||
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<div style="min-height:800px; margin-top:230px;" > | <div style="min-height:800px; margin-top:230px;" > | ||
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+ | <!-- ######################################################################################## | ||
+ | |||
+ | TABLE OBEN | ||
+ | |||
+ | ######################################################################################## --> | ||
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<table id="table_viereck"> | <table id="table_viereck"> | ||
+ | |||
+ | <!-- ######################################################################################## | ||
+ | |||
+ | ABSTRACT | ||
+ | |||
+ | ######################################################################################## --> | ||
+ | |||
+ | |||
<tr> | <tr> | ||
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<td width="450px"> | <td width="450px"> | ||
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<img id="klammer_gross_links" src="https://static.igem.org/mediawiki/2013/e/e0/Freiburg_2013_main2_Rahmen_gross_links.png"> | <img id="klammer_gross_links" src="https://static.igem.org/mediawiki/2013/e/e0/Freiburg_2013_main2_Rahmen_gross_links.png"> | ||
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<div id="text"> | <div id="text"> | ||
- | <p id="text_gross" | + | <p id="text_gross" align="left"> Abstract </p> |
+ | |||
Our Team developed a universal toolkit, termed uniCAS, that enables customizable gene | Our Team developed a universal toolkit, termed uniCAS, that enables customizable gene | ||
regulation in mammalian cells. Therefore, we engineered the recently discovered and highly promising | regulation in mammalian cells. Therefore, we engineered the recently discovered and highly promising | ||
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The regulation is based on the RNA-guided Cas9 protein, which allows targeting of specific DNA sequences. | The regulation is based on the RNA-guided Cas9 protein, which allows targeting of specific DNA sequences. | ||
Our toolkit comprises not only a standardized Cas9 protein, but also different effector domains for | Our toolkit comprises not only a standardized Cas9 protein, but also different effector domains for | ||
- | efficient gene activation or repression. </div> | + | efficient gene activation or repression. |
- | + | </div> | |
+ | |||
+ | <img id="klammer_gross_rechts" src="https://static.igem.org/mediawiki/2013/8/82/Freiburg_2013_main2_Rahmen_gross_rechts.png"> | ||
+ | |||
</td> | </td> | ||
+ | |||
+ | <!-- ######################################################################################## | ||
+ | |||
+ | PROJECT | ||
+ | |||
+ | ######################################################################################## --> | ||
<td> | <td> | ||
+ | |||
<img id="klammer_gross_links" src="https://static.igem.org/mediawiki/2013/e/e0/Freiburg_2013_main2_Rahmen_gross_links.png"> | <img id="klammer_gross_links" src="https://static.igem.org/mediawiki/2013/e/e0/Freiburg_2013_main2_Rahmen_gross_links.png"> | ||
+ | <div id="text-box2"> | ||
+ | <a href="https://2013.igem.org/Team:Freiburg/Project/1"> | ||
+ | <p id="text_gross" align="left"> Our Project </p> | ||
+ | </a> | ||
+ | <div> | ||
- | < | + | <ul style="margin-left:40px;"> |
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- | <li> | + | <li style="margin-top:-30px;"> |
<span> Activation </span> | <span> Activation </span> | ||
- | <img src="https://static.igem.org/mediawiki/2013/0/03/Freiburg_2013_main2_Activation.png" > | + | <img src="https://static.igem.org/mediawiki/2013/0/03/Freiburg_2013_main2_Activation.png"> |
</li> | </li> | ||
- | <li> | + | <li style="margin-left: -40px;"> |
<span> Repression </span> | <span> Repression </span> | ||
<img src="https://static.igem.org/mediawiki/2013/e/e7/Repression_freiburg_13.png"> | <img src="https://static.igem.org/mediawiki/2013/e/e7/Repression_freiburg_13.png"> | ||
</li> | </li> | ||
- | <li> | + | <li style="margin-bottom:-30px;"> |
<span> Epigenetics </span> | <span> Epigenetics </span> | ||
<img src="https://static.igem.org/mediawiki/2013/3/31/Freiburg_2013_main2_Epigenetic.png"> | <img src="https://static.igem.org/mediawiki/2013/3/31/Freiburg_2013_main2_Epigenetic.png"> | ||
</li> | </li> | ||
</ul> | </ul> | ||
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- | <li> | + | <ul style="margin-left:130px;"> |
+ | |||
+ | <li style="margin-top: -30px;"> | ||
<img src="https://static.igem.org/mediawiki/2013/b/bb/Freiburg_2013_main2_Multiple_Targeting.png"> | <img src="https://static.igem.org/mediawiki/2013/b/bb/Freiburg_2013_main2_Multiple_Targeting.png"> | ||
<span> Multiple targeting </span> | <span> Multiple targeting </span> | ||
</li> | </li> | ||
- | <li> | + | <li style="margin-left: 40px;"> |
+ | <img src="https://static.igem.org/mediawiki/2013/e/ef/UniBAss_freiburg_13.png"> | ||
+ | <span> uniBAss</span> | ||
+ | </lI> | ||
+ | |||
+ | <li style="margin-bottom:-30px;"> | ||
<img src="https://static.igem.org/mediawiki/2013/9/9a/Freiburg_2013_main2_Licht.png"> | <img src="https://static.igem.org/mediawiki/2013/9/9a/Freiburg_2013_main2_Licht.png"> | ||
<span> Light switch </span> | <span> Light switch </span> | ||
</li> | </li> | ||
</ul> | </ul> | ||
- | |||
</div> | </div> | ||
+ | </div> | ||
<img id="klammer_gross_rechts" src="https://static.igem.org/mediawiki/2013/8/82/Freiburg_2013_main2_Rahmen_gross_rechts.png"> | <img id="klammer_gross_rechts" src="https://static.igem.org/mediawiki/2013/8/82/Freiburg_2013_main2_Rahmen_gross_rechts.png"> | ||
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+ | <!-- ######################################################################################## | ||
+ | |||
+ | TABLE UNTEN | ||
+ | |||
+ | ######################################################################################## --> | ||
+ | |||
+ | |||
+ | |||
+ | <table id="table_viereck"> | ||
+ | |||
+ | <!-- ######################################################################################## | ||
+ | |||
+ | HIGHLIGHTS | ||
+ | |||
+ | ######################################################################################## --> | ||
+ | |||
+ | |||
+ | <tr> | ||
+ | <td width="300px"> | ||
+ | <img id="klammer_klein_links" src="https://static.igem.org/mediawiki/2013/e/e0/Freiburg_2013_main2_Rahmen_gross_links.png"> | ||
+ | <div id="text-box3-4"> | ||
+ | <p id="text_gross" align="left"> Highlights </p> | ||
+ | <!-- Our Team developed... --> | ||
+ | <div style="z-index:2;"> | ||
+ | <img src="https://static.igem.org/mediawiki/2013/d/d6/Freiburg_2013_main2_Highlights.png" height="50" style="position:relative; top:-30px; left:50px;"> </div> | ||
+ | </div> | ||
+ | <img id="klammer_klein_rechts" src="https://static.igem.org/mediawiki/2013/8/82/Freiburg_2013_main2_Rahmen_gross_rechts.png"> | ||
+ | </td> | ||
+ | |||
+ | |||
+ | <!-- ######################################################################################## | ||
+ | |||
+ | TOOLKIT | ||
+ | |||
+ | ######################################################################################## --> | ||
+ | |||
+ | |||
+ | <td width="300px"> | ||
+ | <img id="klammer_klein_links" src="https://static.igem.org/mediawiki/2013/e/e0/Freiburg_2013_main2_Rahmen_gross_links.png"> | ||
+ | <div id="text-box3-4"> | ||
+ | <a href="https://2013.igem.org/Team:Freiburg/Project/toolkit"> | ||
+ | <p id="text_gross" align="left"> Toolkit </p> | ||
+ | </a> | ||
+ | Use our Toolkit to regulate your genes! | ||
+ | <!-- <img src="https://static.igem.org/mediawiki/2013/d/d9/Freiburg_2013_main2_Toolkit.png" height="80" style="position:relative; top:-100px; left:50px;"> --> | ||
+ | </div> | ||
+ | </div> | ||
+ | |||
+ | <img id="klammer_klein_rechts" src="https://static.igem.org/mediawiki/2013/8/82/Freiburg_2013_main2_Rahmen_gross_rechts.png"> | ||
+ | </td> | ||
+ | |||
+ | |||
+ | <!-- ######################################################################################## | ||
+ | |||
+ | HUMAN PRACTICE | ||
+ | |||
+ | ######################################################################################## --> | ||
+ | |||
+ | |||
+ | <td width="250px"> | ||
+ | <img id="klammer_klein_links" src="https://static.igem.org/mediawiki/2013/e/e0/Freiburg_2013_main2_Rahmen_gross_links.png"> | ||
+ | <div id="text-box5-6"> | ||
+ | <a href="https://2013.igem.org/Team:Freiburg/HumanPractice"> | ||
+ | <p id="text_gross" align="left"> HP </p> | ||
+ | </a> | ||
+ | Our Team developed... </div> | ||
+ | <img id="klammer_klein_rechts" src="https://static.igem.org/mediawiki/2013/8/82/Freiburg_2013_main2_Rahmen_gross_rechts.png"> | ||
+ | </td> | ||
+ | |||
+ | <!-- ######################################################################################## | ||
+ | |||
+ | TEAM | ||
+ | |||
+ | ######################################################################################## --> | ||
+ | |||
+ | |||
+ | <td width="250px"> | ||
+ | <img id="klammer_klein_links" src="https://static.igem.org/mediawiki/2013/e/e0/Freiburg_2013_main2_Rahmen_gross_links.png"> | ||
+ | <div id="text-box5-6"> | ||
+ | <a href="https://2013.igem.org/Team:Freiburg/Team2"> | ||
+ | <p id="text_gross" align="left"> Team </p> | ||
+ | </a> | ||
+ | Our Team developed... </div> | ||
+ | <img id="klammer_klein_rechts" src="https://static.igem.org/mediawiki/2013/8/82/Freiburg_2013_main2_Rahmen_gross_rechts.png"> | ||
+ | </td> | ||
+ | </tr> | ||
+ | </table> | ||
Latest revision as of 16:38, 27 September 2013
Abstract Our Team developed a universal toolkit, termed uniCAS, that enables customizable gene regulation in mammalian cells. Therefore, we engineered the recently discovered and highly promising CRISPR/Cas9 system. The regulation is based on the RNA-guided Cas9 protein, which allows targeting of specific DNA sequences. Our toolkit comprises not only a standardized Cas9 protein, but also different effector domains for efficient gene activation or repression. |
Our Project
|
Highlights |
Toolkit Use our Toolkit to regulate your genes! |
HP Our Team developed... |
Team Our Team developed... |