Team:Freiburg/main2

From 2013.igem.org

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background: url(https://static.igem.org/mediawiki/2013/9/94/Freiburg_2013_main2_Cas.png);
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<div style="min-height:800px; margin-top:230px;" >
<div style="min-height:800px; margin-top:230px;" >
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TABLE OBEN
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  <table id="table_viereck">
  <table id="table_viereck">
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ABSTRACT
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<tr>
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   <img id="klammer_gross_links" src="https://static.igem.org/mediawiki/2013/e/e0/Freiburg_2013_main2_Rahmen_gross_links.png">
   <img id="klammer_gross_links" src="https://static.igem.org/mediawiki/2013/e/e0/Freiburg_2013_main2_Rahmen_gross_links.png">
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  <!-- <p id="text_gross" align="center"> Abstract </p> -->
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   <p id="text_gross" align="left"> Abstract </p>
   <p id="text_gross" align="left"> Abstract </p>
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       The regulation is based on the RNA-guided Cas9 protein, which allows targeting of specific DNA sequences.  
       The regulation is based on the RNA-guided Cas9 protein, which allows targeting of specific DNA sequences.  
       Our toolkit comprises not only a standardized Cas9 protein,  but also different effector domains for  
       Our toolkit comprises not only a standardized Cas9 protein,  but also different effector domains for  
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       efficient gene activation or repression. </div>  
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       efficient gene activation or repression.  
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  <img id="klammer_gross_rechts" src="https://static.igem.org/mediawiki/2013/8/82/Freiburg_2013_main2_Rahmen_gross_rechts.png">  
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</div>  
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  <img id="klammer_gross_rechts" src="https://static.igem.org/mediawiki/2013/8/82/Freiburg_2013_main2_Rahmen_gross_rechts.png">  
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</td>
</td>
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PROJECT
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<td>
<td>
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  <img id="klammer_gross_links" src="https://static.igem.org/mediawiki/2013/e/e0/Freiburg_2013_main2_Rahmen_gross_links.png">
 
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  <div id="text-box2">
 
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  <p id="text_gross" align="left"> Our Project </p>
 
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<div>
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  <img id="klammer_gross_links" src="https://static.igem.org/mediawiki/2013/e/e0/Freiburg_2013_main2_Rahmen_gross_links.png">
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<div id="text-box2">
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  <a href="https://2013.igem.org/Team:Freiburg/Project/1">
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    <p id="text_gross" align="left"> Our Project </p>
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  </a>
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  <div>
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<div style="z-index:2;">
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<ul style="margin-left:40px;">
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<ul>
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<li>
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<li style="margin-top:-30px;">
<span> Activation </span>
<span> Activation </span>
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<img  src="https://static.igem.org/mediawiki/2013/0/03/Freiburg_2013_main2_Activation.png" >
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<img  src="https://static.igem.org/mediawiki/2013/0/03/Freiburg_2013_main2_Activation.png">
</li>
</li>
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<li>
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<li style="margin-left: -40px;">
<span> Repression </span>
<span> Repression </span>
<img  src="https://static.igem.org/mediawiki/2013/e/e7/Repression_freiburg_13.png">
<img  src="https://static.igem.org/mediawiki/2013/e/e7/Repression_freiburg_13.png">
</li>
</li>
    
    
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<li>
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<li style="margin-bottom:-30px;">
<span> Epigenetics </span>
<span> Epigenetics </span>
<img src="https://static.igem.org/mediawiki/2013/3/31/Freiburg_2013_main2_Epigenetic.png">
<img src="https://static.igem.org/mediawiki/2013/3/31/Freiburg_2013_main2_Epigenetic.png">
</li>
</li>
</ul>
</ul>
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</div>
 
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<div style="z-index:1;">
 
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<img id="cas" src="https://static.igem.org/mediawiki/2013/9/94/Freiburg_2013_main2_Cas.png">
 
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</div>
 
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<div style="z-index:2;">
 
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<ul>
 
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<li>
 
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  <img src="https://static.igem.org/mediawiki/2013/e/ef/UniBAss_freiburg_13.png">
 
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<span> uniBAss</span>
 
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</lI>
 
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<li>
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<ul style="margin-left:130px;">
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<li style="margin-top: -30px;">
   <img src="https://static.igem.org/mediawiki/2013/b/bb/Freiburg_2013_main2_Multiple_Targeting.png">
   <img src="https://static.igem.org/mediawiki/2013/b/bb/Freiburg_2013_main2_Multiple_Targeting.png">
<span> Multiple targeting </span>
<span> Multiple targeting </span>
</li>
</li>
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<li>
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<li style="margin-left: 40px;">
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  <img src="https://static.igem.org/mediawiki/2013/e/ef/UniBAss_freiburg_13.png">
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<span> uniBAss</span>
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</lI>
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<li style="margin-bottom:-30px;">
   <img src="https://static.igem.org/mediawiki/2013/9/9a/Freiburg_2013_main2_Licht.png">
   <img src="https://static.igem.org/mediawiki/2013/9/9a/Freiburg_2013_main2_Licht.png">
<span> Light switch </span>
<span> Light switch </span>
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</li>
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</div>
</div>
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HIGHLIGHTS
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  <img id="klammer_klein_links" src="https://static.igem.org/mediawiki/2013/e/e0/Freiburg_2013_main2_Rahmen_gross_links.png">
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  <div id="text-box3-4">
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      <p id="text_gross" align="left"> Highlights </p>
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  <!-- Our Team developed...  -->
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  <img src="https://static.igem.org/mediawiki/2013/d/d6/Freiburg_2013_main2_Highlights.png" height="50" style="position:relative; top:-30px; left:50px;"> </div>
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  </div>
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  <img id="klammer_klein_rechts" src="https://static.igem.org/mediawiki/2013/8/82/Freiburg_2013_main2_Rahmen_gross_rechts.png">
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TOOLKIT
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  <div id="text-box3-4">
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  <a href="https://2013.igem.org/Team:Freiburg/Project/toolkit">
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      <p id="text_gross" align="left"> Toolkit </p>
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  </a>
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  Use our Toolkit to regulate your genes!
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  <!-- <img src="https://static.igem.org/mediawiki/2013/d/d9/Freiburg_2013_main2_Toolkit.png" height="80" style="position:relative; top:-100px; left:50px;"> -->
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  </div>
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  </td>
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HUMAN PRACTICE
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  <img id="klammer_klein_links" src="https://static.igem.org/mediawiki/2013/e/e0/Freiburg_2013_main2_Rahmen_gross_links.png">
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  <div id="text-box5-6">
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  <a href="https://2013.igem.org/Team:Freiburg/HumanPractice">
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      <p id="text_gross" align="left"> HP </p>
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  </a>
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  Our Team developed... </div>
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  <img id="klammer_klein_rechts" src="https://static.igem.org/mediawiki/2013/8/82/Freiburg_2013_main2_Rahmen_gross_rechts.png">
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TEAM
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  <div id="text-box5-6">
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  <a href="https://2013.igem.org/Team:Freiburg/Team2">
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      <p id="text_gross" align="left"> Team </p>
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  </a>
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  Our Team developed... </div>
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  <img id="klammer_klein_rechts" src="https://static.igem.org/mediawiki/2013/8/82/Freiburg_2013_main2_Rahmen_gross_rechts.png">
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  </td>
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</tr>
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</table>

Latest revision as of 16:38, 27 September 2013


Abstract

Our Team developed a universal toolkit, termed uniCAS, that enables customizable gene regulation in mammalian cells. Therefore, we engineered the recently discovered and highly promising CRISPR/Cas9 system. The regulation is based on the RNA-guided Cas9 protein, which allows targeting of specific DNA sequences. Our toolkit comprises not only a standardized Cas9 protein, but also different effector domains for efficient gene activation or repression.

Our Project

  • Activation
  • Repression
  • Epigenetics
  • Multiple targeting
  • uniBAss
  • Light switch

Highlights

Toolkit

Use our Toolkit to regulate your genes!

HP

Our Team developed...

Team

Our Team developed...

Retrieved from "http://2013.igem.org/Team:Freiburg/main2"