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Team:Freiburg
From 2013.igem.org
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| - | <div id="text_gross" align="left"> <a style="position:absolute; top:678px; left: | + | <div id="text_gross" align="left"> <a style="position:absolute; top:678px; left:910px; z-index:2" href="https://2013.igem.org/Team:Freiburg/News"> News </a></div> |
| - | + | <p style="padding-top:10px;"> | |
| - | + | Have a look at our achievements in Lyon & Boston! | |
| + | </p> | ||
| + | <img src="https://static.igem.org/mediawiki/2013/5/56/Best-foundational-advance-2013-freiburg.png" height="130" style="position:absolute; top:600px; left:980px; z-index:1"> | ||
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Latest revision as of 23:52, 9 April 2014
Our Team developed a universal toolkit, termed uniCAS, that enables customizable gene
regulation in mammalian cells. Therefore, we engineered the recently understood and highly promising
CRISPR/Cas9 system.
The regulation is based on the RNA-guided dCas9 protein, which allows specific targeting of DNA sequences. Our toolkit comprises not only a standardized dCas9 protein, but also different effector domains for efficient gene activation or repression. 
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