Team:TU-Eindhoven

From 2013.igem.org

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Latest revision as of 12:52, 26 October 2013

Welcome to the homepage of the TU Eindhoven 2013 iGEM team.

We will create bacteria that can detect tumors
and visualize them on an MRI scan.
Mission Statement of the TU/e iGEM 2013 Team

Our Project
Visualizing tumors using bacteria? Find out what our project is all about!

Learn more...
Wetlab
Take a look at the results of the broad range of experiments performed this year.

Learn more...
Drylab
Various simulations were carried out to support the wetlab experiments.

Learn more...

True. False. Inconclusive.

Which Facts are Synthetic?

Go to Top

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+===Welcome to the homepage of the TU Eindhoven 2013 iGEM team.===
-Within our project we aim to focus on a relatively new form of {{:Team:TU-Eindhoven/Template:Tooltip | text=MRI | tooltip=Magnetic Resonance Imaging }}: {{:Team:TU-Eindhoven/Template:Tooltip | text=CEST | tooltip=Chemical Exchange Saturation Transfer }} imaging. Within CEST imaging proteins containing hydrogen atoms can be used to create the same quality of images as when heavy metals are used. We are hoping to use bacteria to produce these proteins once they enter the body, allowing the bacteria to be our delivery system and production factory. Unique to our process will be the injection of the protein producing bacteria into the patient, as well as the tumor targeting element of the bacteria. Tumors present a {{:Team:TU-Eindhoven/Template:Tooltip | text=hypoxic | tooltip=Low oxygen saturation }} environment, allowing them to be targetted by our bacteria. These hypoxic conditions will furthermore be the trigger for the production of our CEST proteins. This will ensure contrast is created where tumors are present, and also provides a good means of tumor targeting for drug delivery in the future.
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+<html><div class="thumbnail" style="background: url('https://static.igem.org/mediawiki/2013/2/2d/TU-Eindhoven_Images_Header4.jpg') repeat-x center top !important; height: 150px;"><center><div style="font-size: 48pt; line-height: 48pt; text-algin: center; margin-top: 20px; font-weight: bold; color: #555555;">True. False. Inconclusive.</div><div style="font-size: 48pt; line-height: 48pt; text-algin: center; margin-top: -48pt; font-weight: bold; color: #555555;"><span id="tue-sf-true" style="color: #008000; opacity: 0.0;">True.</span> <span id="tue-sf-false" style="color: #FF0000; opacity: 0.0;">False.</span> <span id="tue-sf-undecided" style="color: #0000FF; opacity: 0.0;">Inconclusive.</span></div><br /><a class="btn btn-info" target="_blank" href="http://syntheticfacts.tue.nl">Which Facts are Synthetic?</a></center></div></html>
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