Team:Duke/Team
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'''Website''': [http://buchler.phy.duke.edu// Lab Page] | '''Website''': [http://buchler.phy.duke.edu// Lab Page] | ||
- | The Buchler Lab is interested in the systems biology and evolution of epigenetic switches (bistability) and clocks (oscillators) in gene regulatory networks, two functions that are essential for proper patterning, cell proliferation, and cellular differentiation in biological systems. | + | The Buchler Lab is interested in the systems biology and evolution of epigenetic switches (bistability) and clocks (oscillators) in gene regulatory networks, two functions that are essential for proper patterning, cell proliferation, and cellular differentiation in biological systems. We use several approaches (experiment and theory, biology and physics, evolutionary systems biology and synthetic biology) to understand the diverse molecular and evolutionary mechanisms by which combinatorial control, ultrasensitive thresholds, bistability, and oscillation have evolved in gene networks. |
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Revision as of 05:18, 4 June 2013
Contents |
The Team
Info about the Team
Undergrads
Matt Baron
Short Bio
Matthew Farnitano
Short Bio
Cameron Kim
Short Bio
Hyun Soo Kim
Short Bio
Ashley Reid
Ashley is a rising sophomore from Charlotte, North Carolina majoring in Biomedical Engineering and minoring in Chemistry. As a part of Duke's iGEM team for 2013, I am eager to learn and work with the team to contribute to the exciting project we have in store for this year.
Janan Zhu
Janan is a sophomore from New York, New York majoring in Biophysics and Mathematics. He hopes to work in a field that applies quantitative approaches in understanding biology and is excited to be part of iGEM as a way to explore these interests.
Grad Students
Charlie Cooper
Short Bio
Instructors
Nicolas Buchler, Ph. D.
Short Bio
Website: [http://buchler.phy.duke.edu// Lab Page]
The Buchler Lab is interested in the systems biology and evolution of epigenetic switches (bistability) and clocks (oscillators) in gene regulatory networks, two functions that are essential for proper patterning, cell proliferation, and cellular differentiation in biological systems. We use several approaches (experiment and theory, biology and physics, evolutionary systems biology and synthetic biology) to understand the diverse molecular and evolutionary mechanisms by which combinatorial control, ultrasensitive thresholds, bistability, and oscillation have evolved in gene networks.
Charles A. Gersbach, Ph. D.
Short Bio
Website: [http://gersbach.bme.duke.edu/ Lab Page]
The Gersbach Lab is focused on engineering new methods for directing cell behavior to regenerate diseased or damaged tissues and treat genetic diseases. We are particularly interested in developing and applying technologies that manipulate cellular processes at the genetic level. Our work capitalizes on the products of the Genomic Revolution and modern advances in the fields of genetic reprogramming, gene delivery, protein engineering, stem cell transplantation, and synthetic biology to create innovative biologic approaches to improving human health. These studies also facilitate a better understanding of complex processes including organogenesis, cell lineage determination, and gene regulation that will ultimately lead to improved design of drugs and biotherapeutics. Our efforts are catalyzed by interdisciplinary collaborations with investigators in engineering and medicine at Duke and other institutions.