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Team:Freiburg/main2
From 2013.igem.org
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<img id="activation" src="https://static.igem.org/mediawiki/2013/0/03/Freiburg_2013_main2_Activation.png"> | <img id="activation" src="https://static.igem.org/mediawiki/2013/0/03/Freiburg_2013_main2_Activation.png"> | ||
<img id="epigenetic"src="https://static.igem.org/mediawiki/2013/3/31/Freiburg_2013_main2_Epigenetic.png"> | <img id="epigenetic"src="https://static.igem.org/mediawiki/2013/3/31/Freiburg_2013_main2_Epigenetic.png"> | ||
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<img id="klammer_gross" src="https://static.igem.org/mediawiki/2013/8/82/Freiburg_2013_main2_Rahmen_gross_rechts.png"> | <img id="klammer_gross" src="https://static.igem.org/mediawiki/2013/8/82/Freiburg_2013_main2_Rahmen_gross_rechts.png"> | ||
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Revision as of 19:41, 26 September 2013
Abstract Our Team developed a universal toolkit, termed uniCAS, that enables customizable gene regulation in mammalian cells. Therefore, we engineered the recently discovered and highly promising CRISPR/Cas9 system. The regulation is based on the RNA-guided Cas9 protein, which allows targeting of specific DNA sequences. Our toolkit comprises not only a standardized Cas9 protein, but also different effector domains for efficient gene activation or repression. 
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