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Team:HZAU-China/Home
From 2013.igem.org
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| - | <p style="font-family:Arial,Helvetica,sans-serif;font-size:17px;font-color:#000;text-align:justify;padding:10px; margin:0px;">55000 people die of rabies per year and about 95% of human deaths occur in Asia and Africa. We hope our project can reach the WHO goal of being free of human rabies by 2020. The section shows the core consideration of our project. | + | <p style="font-family:Arial,Helvetica,sans-serif;font-size:17px;font-color:#000;text-align:justify; padding:10px;margin:0px;">55000 people die of rabies per year and about 95% of human deaths occur in Asia and Africa. We hope our project can reach the WHO goal of being free of human rabies by 2020. The section shows the core consideration of our project. |
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Revision as of 06:36, 27 September 2013
PROJECT: Safe Moving Vaccine Factory
ABSTRACT
Our idea comes from Yersinia pestis and fleas. We make use of fleas as our moving injector. When flea feed blood from dogs, our vaccine vector Bacillus subtilis will be regurgitated into blood and successfully transferred to mammalian host. Bacillus subtilis can express antigens which can stimulate the immunity of dogs. Meanwhile, endogenous or exogenous expression of "Antimicrobial Peptides" by B. subtilis can kill Yersinia pestis in fleas. In this way we achieved a safe moving vaccine factory.
