Team:NYMU-Taipei/Modeling/MainParts

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National Yang Ming University

Main Parts

Main part model

Background:

Circuit regulators:

• LacI-regulated promoter (pLac) : when LacI exists, it will bind to LacI-regulated promoter (pLac) and represses the promoter.

• pLux/Ci hybrid promoter(plux/cI) : when luxR/AHL exists, it will open pLux/cI hybrid promoter(plux/cI), while cI will repress the promoter. What’s more, plux/cI is cI-dominant, which means when cI exists, the hybrid promoter will be repressed whether luxR/AHL exists or not.

Circuit regulation:

•Circuit condition without Nosema:

Without NosemaCeranae, the first circuit will not open, and thus, no LacI will be produced. Since there is no LacI binding to pLac, pLac will not be repressed, and thus cI will be produced. After that, cI will bind to pLux/cI hybrid promoter, leading the third circuit to be off.

•Circuit condition with Nosema:

When Nosema Ceranae infects the bee, bee’s immune system will be activated, leading to the concentration of ROS (reactive oxygen species) to be high. In response, Bee. coli will enhance the production of oxyR, which forms a complex with ROS and binds to transcription binding site ahead of trxC (an oxyR-activated promoter; namely, the sensor), leading to the first circuit to be on.

Since the first circuit is on, the downstream LacI gene will be produced and bind to pLac, leading to the second circuit to be off.

After the second circuit is closed, no cI is produced, leading to the third circuit to be on (no repressor at all). And then, kill protein will be produced and kill Nosema Ceranae.

•Positive feedback:

Besides the LuxI and LuxR(which then form a complex called luxR/AHL) produced by first circuit, the third circuit will also produce LuxI and LuxR, which acts as a positive feedback and strongly enhances the production of killer protein.

•Circuit condition when Nosema is killed:

After Nosema is killed, the sensor will be off and no lacI will be produced.

Without LacI, the pLac will not be repressed, and the second circuit will be on, leading to the production of cI. After cI binds to pLux/cI hybrid promoter, the third circuit to be off. After that, the overall circuit will switch to the beginning stage when there is no Nosema.

Aims:

1. To know how much time it needs from sensing to killing the Nosema after infection

2. To know whether the pathway is effective or not

3. To know the range of kill protein concentration (from the minimal concentration which Is effective to kill Nosema to the maximal concentration which will not do harm to the bees)

It is assumed that AHL is abundant and thus the formation of AHL2LuxR complex is determined only by the concentration of LuxR; CI’s mechanism of binding to the promoter is assumed to act as hill effect form; kill protein will sustain a period of time before it is degraded naturally without any other types of decomposition.

‧Equation1:

KdLacI = dissociation constant of CI

nLacI = Hill coefficient of LacI

PoPSpLac = promoter strength of pLac

kdegmRNA = degrading constant of sensor promoter mRNA

N = number of plasmid in a single cell

V = volume of a cell

The aim of the equation is to knowmRNACI production rate and when it can reach the level to translate the desired concentration.

‧Equation2:

KdROSoxyR = dissociation constant ofROSoxyR

nROSoxyR = Hill coefficient of ROSoxyR

PoPStrxC = promoter strength of trxC

kdegmRNA = degrading constant of sensor promoter mRNA

N = number of plasmid in a single cell

V = volume of a cell

The aim of the equation is to know how trxC promoter strength (in PoPS) influences the production of lacI.

‧Equation3:

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-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>1</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r></span></i></b><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>(</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>1</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>cI</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr> </m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>leak</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>ncI</m:r></span></i></b></m:sup></m:sSup></m:num><m:den><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>KdcI</m:r></span></i></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLacI</m:r></span></i></b></m:sup></m:sSup><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r></span></i></b><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>cI</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>ncI</m:r></span></i></b></m:sup></m:sSup></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>×</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>Po&#55349;&#56439;SLuxcI</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>×</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>N</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>/</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>V</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>kdegmRNA</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>×[</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>mRNAluxI</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>]</m:r></span></i></b></m:oMath></m:oMathPara><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;mso-ansi-language:EN-US;mso-fareast-language:
-ZH-TW;mso-bidi-language:AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75"
- style='width:415.5pt;height:90pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image008.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>KdROSoxyR = dissociation constant ofROSoxyR<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>nROSoxyR = Hill coefficient of ROSoxyR<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>PoPStrxC = promoter strength of trxC<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>KdLuxRAHL = dissociation constant ofLuxRAHL<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>nLuxRAHL = Hill coefficient of LuxRAHL<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>KdcI = dissociation constant ofcI<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>ncI = Hill coefficient ofCi<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>PoPSLuxcI = promoter strength of LuxcI
-hybrid promoter<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>kdegmRNA = degrading constant of sensor
-promoter mRNA<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>N = number of plasmid in a single cell <o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>V = volume of a cell<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'><o:p>&nbsp;</o:p></span></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US>The aim of the equation is to know how trxC promoter strength (in
-PoPS) influences the production of LuxI.</span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US style='font-size:10.0pt'><o:p>&nbsp;</o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><span
-style='font-family:"新細明體","serif"'>‧</span><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US>Equation5:<o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><!--[if gte msEquation 12]><m:oMathPara><m:oMath><m:f><m:fPr><span
-    style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><b style='mso-bidi-font-weight:
-    normal'><i style='mso-bidi-font-style:normal'><span lang=EN-US
-    style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>d</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>mRNALuxR</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:num><m:den><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>dt</m:r></span></i></b></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>=</m:r></span></i></b><m:f><m:fPr><span
-    style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>ROSoxyR</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nROSoxyR</m:r></span></i></b></m:sup></m:sSup></m:num><m:den><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>KdROSoxyR</m:r></span></i></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nROSoxyR</m:r></span></i></b></m:sup></m:sSup><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r></span></i></b><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>ROSoxyR</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nROSoxyR</m:r></span></i></b></m:sup></m:sSup></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>×</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>PoPStrxC</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>×</m:r></span></i></b><m:f><m:fPr><span
-    style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>N</m:r></span></i></b></m:num><m:den><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>V</m:r></span></i></b></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r></span></i></b><m:f><m:fPr><span
-    style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><m:d><m:dPr><m:begChr
-         m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;
-        mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-        mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-        font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;
-        mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-        style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-        lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-           m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxRAHL</m:r></span></i></b></m:e></m:d></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLuxRAHL</m:r></span></i></b></m:sup></m:sSup></m:num><m:den><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>KdLuxRAHL</m:r></span></i></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLuxRAHL</m:r></span></i></b></m:sup></m:sSup><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r></span></i></b><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><m:d><m:dPr><m:begChr
-         m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;
-        mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-        mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-        font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;
-        mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-        style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-        lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-           m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxRAHL</m:r></span></i></b></m:e></m:d></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLuxRAHL</m:r></span></i></b></m:sup></m:sSup></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>×(</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>1</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r></span></i></b><m:f><m:fPr><span
-    style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>(</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>1</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>cI</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr> </m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>leak</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>ncI</m:r></span></i></b></m:sup></m:sSup></m:num><m:den><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>KdcI</m:r></span></i></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLacI</m:r></span></i></b></m:sup></m:sSup><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r></span></i></b><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><m:d><m:dPr><m:begChr
-         m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;
-        mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-        mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-        font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;
-        mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-        style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-        lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-           m:val="roman"/><m:sty m:val="bi"/></m:rPr>cI</m:r></span></i></b></m:e></m:d></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>ncI</m:r></span></i></b></m:sup></m:sSup></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>)×</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>PoPSLuxcI</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>×</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>N</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>/</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>V</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>kdegmRNA</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>×[</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>mRNAluxR</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>]</m:r></span></i></b></m:oMath></m:oMathPara><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;mso-ansi-language:EN-US;mso-fareast-language:
-ZH-TW;mso-bidi-language:AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75"
- style='width:415.5pt;height:90pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image009.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>KdROSoxyR = dissociation constant ofROSoxyR<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>nROSoxyR = Hill coefficient of ROSoxyR<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>PoPStrxC = promoter strength of trxC<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>KdLuxRAHL = dissociation constant ofLuxRAHL<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>nLuxRAHL = Hill coefficient of LuxRAHL<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>KdcI = dissociation constant ofcI<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>ncI = Hill coefficient ofCi<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>PoPSLuxcI = promoter strength of LuxcI
-hybrid promoter<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>kdegmRNA = degrading constant of sensor
-promoter mRNA<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>N = number of plasmid in a single cell <o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>V = volume of a cell<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'><o:p>&nbsp;</o:p></span></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US>The aim of the equation is to know how trxC promoter strength (in
-PoPS) influences the production of LuxR.</span></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US><o:p>&nbsp;</o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><span
-style='font-family:"新細明體","serif"'>‧</span><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US>Equation6:<o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><!--[if gte msEquation 12]><m:oMathPara><m:oMath><m:f><m:fPr><span
-    style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><b style='mso-bidi-font-weight:
-    normal'><i style='mso-bidi-font-style:normal'><span lang=EN-US
-    style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>d</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>mRNAkill</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:num><m:den><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>dt</m:r></span></i></b></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>=</m:r></span></i></b><m:f><m:fPr><span
-    style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxRAHL</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLuxRAHL</m:r></span></i></b></m:sup></m:sSup></m:num><m:den><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>KdLuxRAHL</m:r></span></i></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLuxRAHL</m:r></span></i></b></m:sup></m:sSup><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r></span></i></b><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxRAHL</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLuxRAHL</m:r></span></i></b></m:sup></m:sSup></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>×(</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>1</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r></span></i></b><m:f><m:fPr><span
-    style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>(</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>1</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>cI</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr> </m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>leak</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>ncI</m:r></span></i></b></m:sup></m:sSup></m:num><m:den><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>KdcI</m:r></span></i></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLacI</m:r></span></i></b></m:sup></m:sSup><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r></span></i></b><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><m:d><m:dPr><m:begChr
-         m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;
-        mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-        mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-        font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;
-        mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-        style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-        lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-           m:val="roman"/><m:sty m:val="bi"/></m:rPr>cI</m:r></span></i></b></m:e></m:d></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>ncI</m:r></span></i></b></m:sup></m:sSup></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>)×</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>PoPSLuxcI</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>×</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>N</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>/</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>V</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>kdegmRNA</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>×[</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>mRNAkill</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>]</m:r></span></i></b></m:oMath></m:oMathPara><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;mso-ansi-language:EN-US;mso-fareast-language:
-ZH-TW;mso-bidi-language:AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75"
- style='width:415.5pt;height:54pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image010.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>KdLuxRAHL = dissociation constant ofLuxRAHL<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>nLuxRAHL = Hill coefficient of LuxRAHL<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>KdcI = dissociation constant ofcI<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>ncI = Hill coefficient ofCi<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>PoPSLuxcI = promoter strength of LuxcI
-hybrid promoter<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>kdegmRNA = degrading constant of sensor
-promoter mRNA<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>N = number of plasmid in a single cell <o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>V = volume of a cell<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US><o:p>&nbsp;</o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US>The aim of the equation is
-to knowmRNA of kill protein production rate and when it can reach the level ofthe
-desired concentration.<o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US><o:p>&nbsp;</o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><span
-style='font-family:"新細明體","serif"'>‧</span><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US>Equation7:<o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><!--[if gte msEquation 12]><m:oMathPara><m:oMath><m:f><m:fPr><span
-    style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><b style='mso-bidi-font-weight:
-    normal'><i style='mso-bidi-font-style:normal'><span lang=EN-US
-    style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>d</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>mRNAT7</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:num><m:den><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>dt</m:r></span></i></b></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>=</m:r></span></i></b><m:f><m:fPr><span
-    style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>ROSoxyR</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nROSoxyR</m:r></span></i></b></m:sup></m:sSup></m:num><m:den><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>KdROSoxyR</m:r></span></i></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nROSoxyR</m:r></span></i></b></m:sup></m:sSup><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r></span></i></b><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>ROSoxyR</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nROSoxyR</m:r></span></i></b></m:sup></m:sSup></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>×</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>PoPStrxC</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>×</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>N</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>/</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>V</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>×</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>a</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>+</m:r></span></i></b><m:f><m:fPr><span
-    style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>T7</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nT7</m:r></span></i></b></m:sup></m:sSup></m:num><m:den><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>KdT7</m:r></span></i></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nT7</m:r></span></i></b></m:sup></m:sSup><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r></span></i></b><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>T7</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nY7</m:r></span></i></b></m:sup></m:sSup></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>×</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>PoPST7</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>×</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>N</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>/</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>V</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>kdegmRNA</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>×[</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>mRNAT7</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>]</m:r></span></i></b></m:oMath></m:oMathPara><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;mso-ansi-language:EN-US;mso-fareast-language:
-ZH-TW;mso-bidi-language:AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75"
- style='width:415.5pt;height:1in'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image011.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>KdROSoxyR = dissociation constant ofROSoxyR<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>nROSoxyR = Hill coefficient of ROSoxyR<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>PoPStrxC = promoter strength of trxC<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>KdT7 = dissociation constant of T7<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>NT7 = Hill coefficient of T7<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>PoPST7 = promoter strength of T7 promoter<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>kdegmRNA = degrading constant of sensor
-promoter mRNA<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>N = number of plasmid in a single cell <o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>V = volume of a cell<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'><o:p>&nbsp;</o:p></span></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US>The aim of the equation is
-to knowmRNA of T7 polymerase production rate and when it can reach the level to
-translate enough T7 polymerase.<o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US style='font-size:10.0pt'><o:p>&nbsp;</o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><span
-style='font-family:"新細明體","serif"'>‧</span><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US>Equation8:<o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><!--[if gte msEquation 12]><m:oMathPara><m:oMath><m:f><m:fPr><span
-    style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><b style='mso-bidi-font-weight:
-    normal'><i style='mso-bidi-font-style:normal'><span lang=EN-US
-    style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>d</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>mRNAPDC</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:num><m:den><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>dt</m:r></span></i></b></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>=</m:r></span></i></b><m:f><m:fPr><span
-    style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>T7</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nT7</m:r></span></i></b></m:sup></m:sSup></m:num><m:den><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>KdT7</m:r></span></i></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nT7</m:r></span></i></b></m:sup></m:sSup><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r></span></i></b><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>T7</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nY7</m:r></span></i></b></m:sup></m:sSup></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>×</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>PoPST7</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>×</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>N</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>/</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>V</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>kdegmRNA</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>×[</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>mRNAPDC</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>]</m:r></span></i></b></m:oMath></m:oMathPara><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;mso-ansi-language:EN-US;mso-fareast-language:
-ZH-TW;mso-bidi-language:AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75"
- style='width:378.75pt;height:36pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image012.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>KdT7 = dissociation constant of T7<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>NT7 = Hill coefficient of T7<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>PoPST7 = promoter strength of T7 promoter<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>kdegmRNA = degrading constant of sensor
-promoter mRNA<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>N = number of plasmid in a single cell <o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>V = volume of a cell<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'><o:p>&nbsp;</o:p></span></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US>The aim of the equation is
-to knowmRNA of enzyme PDC production rate and when it can reach the level to
-translate enough PDC.<o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'><o:p>&nbsp;</o:p></span></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><span
-style='font-family:"新細明體","serif"'>‧</span><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US>Equation9:<o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><!--[if gte msEquation 12]><m:oMathPara><m:oMath><m:f><m:fPr><span
-    style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><b style='mso-bidi-font-weight:
-    normal'><i style='mso-bidi-font-style:normal'><span lang=EN-US
-    style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>d</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>mRNAADH</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:num><m:den><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>dt</m:r></span></i></b></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>=</m:r></span></i></b><m:f><m:fPr><span
-    style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>T7</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nT7</m:r></span></i></b></m:sup></m:sSup></m:num><m:den><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>KdT7</m:r></span></i></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nT7</m:r></span></i></b></m:sup></m:sSup><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r></span></i></b><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>T7</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nY7</m:r></span></i></b></m:sup></m:sSup></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>×</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>PoPST7</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>×</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>N</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>/</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>V</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>kdegmRNA</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>×[</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>mRNAADH</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>]</m:r></span></i></b></m:oMath></m:oMathPara><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;mso-ansi-language:EN-US;mso-fareast-language:
-ZH-TW;mso-bidi-language:AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75"
- style='width:381pt;height:36pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image013.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>KdT7 = dissociation constant of T7<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>NT7 = Hill coefficient of T7<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>PoPST7 = promoter strength of T7 promoter<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>kdegmRNA = degrading constant of sensor
-promoter mRNA<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>N = number of plasmid in a single cell <o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>V = volume of a cell<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'><o:p>&nbsp;</o:p></span></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US>The aim of the equation is
-to knowmRNA of enzyme ADH production rate and when it can reach the level to
-translate enough ADH.<o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'><o:p>&nbsp;</o:p></span></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><span
-style='font-family:"新細明體","serif"'>‧</span><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US>Equation10:<o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><!--[if gte msEquation 12]><m:oMathPara><m:oMathParaPr><m:jc
-   m:val="left"/></m:oMathParaPr><m:oMath><m:f><m:fPr><span style='font-size:
-.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:
-    "Cambria Math","serif";mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:
-    "Cambria Math";font-weight:bold;mso-bidi-font-weight:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>d</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>CI</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:num><m:den><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>dt</m:r></span></i></b></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>=</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>RBS</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>×</m:r></span></i></b><m:d><m:dPr><m:begChr m:val="["/><m:endChr
-     m:val="]"/><span style='font-size:10.0pt;mso-ansi-font-size:10.0pt;
-    mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:
-    "Cambria Math";mso-hansi-font-family:"Cambria Math";font-weight:bold;
-    mso-bidi-font-weight:normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>mRNAcI</m:r></span></i></b></m:e></m:d><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>KdegCI</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>CI</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:oMath></m:oMathPara><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;mso-ansi-language:EN-US;mso-fareast-language:
-ZH-TW;mso-bidi-language:AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75"
- style='width:182.25pt;height:36pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image014.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>RBS = binding site strength<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>KdegCI = degrading constant of CI<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US><o:p>&nbsp;</o:p></span></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US>The aim of the equation is
-to know the production rate of CI and when it can reach the concentration to
-repress LuxCI hybrid promoter.<o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US><o:p>&nbsp;</o:p></span></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><span
-style='font-family:"新細明體","serif"'>‧</span><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US>Equation11:<o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><!--[if gte msEquation 12]><m:oMathPara><m:oMathParaPr><m:jc
-   m:val="left"/></m:oMathParaPr><m:oMath><m:f><m:fPr><span style='font-size:
-.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:
-    "Cambria Math","serif";mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:
-    "Cambria Math";font-weight:bold;mso-bidi-font-weight:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>d</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>LacI</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:num><m:den><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>dt</m:r></span></i></b></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>=</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>RBS</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>×</m:r></span></i></b><m:d><m:dPr><m:begChr m:val="["/><m:endChr
-     m:val="]"/><span style='font-size:10.0pt;mso-ansi-font-size:10.0pt;
-    mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:
-    "Cambria Math";mso-hansi-font-family:"Cambria Math";font-weight:bold;
-    mso-bidi-font-weight:normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>mRNALacI</m:r></span></i></b></m:e></m:d><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>KdegCI</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>LacI</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:oMath></m:oMathPara><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;mso-ansi-language:EN-US;mso-fareast-language:
-ZH-TW;mso-bidi-language:AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75"
- style='width:215.25pt;height:36pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image015.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>RBS = binding site strength<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>KdegLacI = degrading constant of LacI<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'><o:p>&nbsp;</o:p></span></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US>The aim of the equation is
-to knowLacI production rate and when it can reach the concentration to repress
-promoter LacI<o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'><o:p>&nbsp;</o:p></span></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><span
-style='font-family:"新細明體","serif"'>‧</span><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US>Equation12:<o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><!--[if gte msEquation 12]><m:oMathPara><m:oMath><m:f><m:fPr><span
-    style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><b style='mso-bidi-font-weight:
-    normal'><i style='mso-bidi-font-style:normal'><span lang=EN-US
-    style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>d</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxI</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:num><m:den><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>dt</m:r></span></i></b></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>=</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>RBS</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>×</m:r></span></i></b><m:d><m:dPr><m:begChr m:val="["/><m:endChr
-     m:val="]"/><span style='font-size:10.0pt;mso-ansi-font-size:10.0pt;
-    mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:
-    "Cambria Math";mso-hansi-font-family:"Cambria Math";font-weight:bold;
-    mso-bidi-font-weight:normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>mRNALuxI</m:r></span></i></b></m:e></m:d><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>KAHL</m:r></span></i></b><m:d><m:dPr><m:begChr m:val="["/><m:endChr
-     m:val="]"/><span style='font-size:10.0pt;mso-ansi-font-size:10.0pt;
-    mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:
-    "Cambria Math";mso-hansi-font-family:"Cambria Math";font-weight:bold;
-    mso-bidi-font-weight:normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxI</m:r></span></i></b></m:e></m:d><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>KdegLuxI</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxI</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:oMath></m:oMathPara><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;mso-ansi-language:EN-US;mso-fareast-language:
-ZH-TW;mso-bidi-language:AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75"
- style='width:298.5pt;height:36pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image016.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><span lang=EN-US><b style='mso-bidi-font-weight:
-normal'><o:p></o:p></b></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>RBS = binding site strength<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>KAHL = LuxI</span><span lang=EN-US
-style='font-size:10.0pt;font-family:Wingdings;mso-ascii-font-family:Calibri;
-mso-ascii-theme-font:minor-latin;mso-hansi-font-family:Calibri;mso-hansi-theme-font:
-minor-latin;mso-char-type:symbol;mso-symbol-font-family:Wingdings'><span
-style='mso-char-type:symbol;mso-symbol-font-family:Wingdings'>&agrave;</span></span><span
-lang=EN-US style='font-size:10.0pt'>AHL rate constant<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>KdegLuxI = degrading constant of LuxI<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US><o:p>&nbsp;</o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US>The aim of the equation is
-to know the production rate of LuxI concerning the LuxI</span></b><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US style='font-family:Wingdings;
-mso-ascii-font-family:Calibri;mso-ascii-theme-font:minor-latin;mso-hansi-font-family:
-Calibri;mso-hansi-theme-font:minor-latin;mso-char-type:symbol;mso-symbol-font-family:
-Wingdings'><span style='mso-char-type:symbol;mso-symbol-font-family:Wingdings'>&agrave;</span></span><span
-lang=EN-US>AHL reaction and LuxI degrading.<o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US><o:p>&nbsp;</o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><span
-style='font-family:"新細明體","serif"'>‧</span><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US>Equation13:<o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><!--[if gte msEquation 12]><m:oMathPara><m:oMath><m:f><m:fPr><span
-    style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><b style='mso-bidi-font-weight:
-    normal'><i style='mso-bidi-font-style:normal'><span lang=EN-US
-    style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>d</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxR</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:num><m:den><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>dt</m:r></span></i></b></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>=</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>RBS</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>×</m:r></span></i></b><m:d><m:dPr><m:begChr m:val="["/><m:endChr
-     m:val="]"/><span style='font-size:10.0pt;mso-ansi-font-size:10.0pt;
-    mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:
-    "Cambria Math";mso-hansi-font-family:"Cambria Math";font-weight:bold;
-    mso-bidi-font-weight:normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>mRNALuxR</m:r></span></i></b></m:e></m:d><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>KmAHL</m:r></span></i></b><m:d><m:dPr><m:begChr m:val="["/><m:endChr
-     m:val="]"/><span style='font-size:10.0pt;mso-ansi-font-size:10.0pt;
-    mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:
-    "Cambria Math";mso-hansi-font-family:"Cambria Math";font-weight:bold;
-    mso-bidi-font-weight:normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>AHL</m:r></span></i></b></m:e></m:d><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>KdegLuxR</m:r></span></i></b><m:d><m:dPr><m:begChr
-     m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;mso-ansi-font-size:
-.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-    mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-    font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;mso-bidi-font-style:
-    normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b style='mso-bidi-font-weight:
-    normal'><i style='mso-bidi-font-style:normal'><span lang=EN-US
-    style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxR</m:r></span></i></b></m:e></m:d><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>KonAHL</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>×</m:r></span></i></b><m:sSup><m:sSupPr><span
-    style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><m:d><m:dPr><m:begChr
-       m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;
-      mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-      mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-      font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;
-      mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>AHL</m:r></span></i></b></m:e></m:d></m:e><m:sup><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>2</m:r></span></i></b></m:sup></m:sSup><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>×</m:r></span></i></b><m:d><m:dPr><m:begChr
-     m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;mso-ansi-font-size:
-.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-    mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-    font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;mso-bidi-font-style:
-    normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b style='mso-bidi-font-weight:
-    normal'><i style='mso-bidi-font-style:normal'><span lang=EN-US
-    style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxR</m:r></span></i></b></m:e></m:d><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>KdegAHL</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>AHL</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:oMath></m:oMathPara><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;mso-ansi-language:EN-US;mso-fareast-language:
-ZH-TW;mso-bidi-language:AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75"
- style='width:415.5pt;height:54pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image017.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><span lang=EN-US><b style='mso-bidi-font-weight:
-normal'><o:p></o:p></b></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>RBS = binding site strength<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>KmAHL =AHL</span><span lang=EN-US
-style='font-size:10.0pt;font-family:Wingdings;mso-ascii-font-family:Calibri;
-mso-ascii-theme-font:minor-latin;mso-hansi-font-family:Calibri;mso-hansi-theme-font:
-minor-latin;mso-char-type:symbol;mso-symbol-font-family:Wingdings'><span
-style='mso-char-type:symbol;mso-symbol-font-family:Wingdings'>&agrave;</span></span><span
-lang=EN-US style='font-size:10.0pt'>LuxI rate constant<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>KdegLuxR= degrading constant of LuxR<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>KonAHL = 2AHL + LuxR</span><span
-lang=EN-US style='font-size:10.0pt;font-family:Wingdings;mso-ascii-font-family:
-Calibri;mso-ascii-theme-font:minor-latin;mso-hansi-font-family:Calibri;
-mso-hansi-theme-font:minor-latin;mso-char-type:symbol;mso-symbol-font-family:
-Wingdings'><span style='mso-char-type:symbol;mso-symbol-font-family:Wingdings'>&agrave;</span></span><span
-lang=EN-US style='font-size:10.0pt'>(AHL)2/LuxR complex rate constant<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>KdegAHL = degrading constant of AHL<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US><o:p>&nbsp;</o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US>The aim of the equation is
-to know the production rate of LuxR concerning the 2AHL + LuxR </span></b><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US style='font-family:Wingdings;
-mso-ascii-font-family:Calibri;mso-ascii-theme-font:minor-latin;mso-hansi-font-family:
-Calibri;mso-hansi-theme-font:minor-latin;mso-char-type:symbol;mso-symbol-font-family:
-Wingdings'><span style='mso-char-type:symbol;mso-symbol-font-family:Wingdings'>&agrave;</span></span><span
-lang=EN-US> (AHL)2/LuxR reaction , AHL </span></b><b style='mso-bidi-font-weight:
-normal'><span lang=EN-US style='font-family:Wingdings;mso-ascii-font-family:
-Calibri;mso-ascii-theme-font:minor-latin;mso-hansi-font-family:Calibri;
-mso-hansi-theme-font:minor-latin;mso-char-type:symbol;mso-symbol-font-family:
-Wingdings'><span style='mso-char-type:symbol;mso-symbol-font-family:Wingdings'>&agrave;</span></span><span
-lang=EN-US> LuxI reaction, and LuxR, AHL degrading.<o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US><o:p>&nbsp;</o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><span
-style='font-family:"新細明體","serif"'>‧</span><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US>Equation14:<o:p></o:p></span></b></p>
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-    style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><b style='mso-bidi-font-weight:
-    normal'><i style='mso-bidi-font-style:normal'><span lang=EN-US
-    style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>d</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>AHL</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:num><m:den><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>dt</m:r></span></i></b></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
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-     m:val="bi"/></m:rPr>×</m:r></span></i></b><m:d><m:dPr><m:begChr m:val="["/><m:endChr
-     m:val="]"/><span style='font-size:10.0pt;mso-ansi-font-size:10.0pt;
-    mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:
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-    mso-bidi-font-weight:normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxI</m:r></span></i></b></m:e></m:d><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>2</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>×</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>KoffAHL</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>×</m:r></span></i></b><m:d><m:dPr><m:begChr
-     m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;mso-ansi-font-size:
-.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-    mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-    font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;mso-bidi-font-style:
-    normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b style='mso-bidi-font-weight:
-    normal'><i style='mso-bidi-font-style:normal'><span lang=EN-US
-    style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>AHLLuxR</m:r></span></i></b></m:e></m:d><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>2</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>×</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>KonAHL</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>×</m:r></span></i></b><m:sSup><m:sSupPr><span
-    style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
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-      mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-      mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-      font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;
-      mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
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-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
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-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>×</m:r></span></i></b><m:d><m:dPr><m:begChr
-     m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;mso-ansi-font-size:
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-    mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-    font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;mso-bidi-font-style:
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-    style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxR</m:r></span></i></b></m:e></m:d><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>KdegAHL</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>AHL</m:r><m:r><m:rPr><m:scr
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-normal'><o:p></o:p></b></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>KAHL = LuxI</span><span lang=EN-US
-style='font-size:10.0pt;font-family:Wingdings;mso-ascii-font-family:Calibri;
-mso-ascii-theme-font:minor-latin;mso-hansi-font-family:Calibri;mso-hansi-theme-font:
-minor-latin;mso-char-type:symbol;mso-symbol-font-family:Wingdings'><span
-style='mso-char-type:symbol;mso-symbol-font-family:Wingdings'>&agrave;</span></span><span
-lang=EN-US style='font-size:10.0pt'>AHL rate constant<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>KonAHL = 2AHL + LuxR</span><span
-lang=EN-US style='font-size:10.0pt;font-family:Wingdings;mso-ascii-font-family:
-Calibri;mso-ascii-theme-font:minor-latin;mso-hansi-font-family:Calibri;
-mso-hansi-theme-font:minor-latin;mso-char-type:symbol;mso-symbol-font-family:
-Wingdings'><span style='mso-char-type:symbol;mso-symbol-font-family:Wingdings'>&agrave;</span></span><span
-lang=EN-US style='font-size:10.0pt'>(AHL)2/LuxR complex rate constant<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>KoffAHL = (AHL)2/LuxR complex</span><span
-lang=EN-US style='font-size:10.0pt;font-family:Wingdings;mso-ascii-font-family:
-Calibri;mso-ascii-theme-font:minor-latin;mso-hansi-font-family:Calibri;
-mso-hansi-theme-font:minor-latin;mso-char-type:symbol;mso-symbol-font-family:
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-lang=EN-US style='font-size:10.0pt'>2AHL + LuxR rate constant<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>KdegAHL = degrading constant of AHL<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US><o:p>&nbsp;</o:p></span></b></p>
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- <v:path arrowok="t"/>
-</v:shape><b style='mso-bidi-font-weight:normal'><span lang=EN-US>The aim of
-the equation is to know the production rate of AHL concerning the LuxI</span></b><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US style='font-family:Wingdings;
-mso-ascii-font-family:Calibri;mso-ascii-theme-font:minor-latin;mso-hansi-font-family:
-Calibri;mso-hansi-theme-font:minor-latin;mso-char-type:symbol;mso-symbol-font-family:
-Wingdings'><span style='mso-char-type:symbol;mso-symbol-font-family:Wingdings'>&agrave;</span></span><span
-lang=EN-US>AHL reaction, 2AHL + LuxR<span
-style='mso-spacerun:yes'>&nbsp;&nbsp;&nbsp; </span>(AHL)2/LuxR reaction and AHL
-degrading.<o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US><o:p>&nbsp;</o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><span
-style='font-family:"新細明體","serif"'>‧</span><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US>Equation15:<o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><!--[if gte msEquation 12]><m:oMathPara><m:oMathParaPr><m:jc
-   m:val="left"/></m:oMathParaPr><m:oMath><m:f><m:fPr><span style='font-size:
-.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:
-    "Cambria Math","serif";mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:
-    "Cambria Math";font-weight:bold;mso-bidi-font-weight:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>d</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>T7</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:num><m:den><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>dt</m:r></span></i></b></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>=</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>RBS</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>×</m:r></span></i></b><m:d><m:dPr><m:begChr m:val="["/><m:endChr
-     m:val="]"/><span style='font-size:10.0pt;mso-ansi-font-size:10.0pt;
-    mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:
-    "Cambria Math";mso-hansi-font-family:"Cambria Math";font-weight:bold;
-    mso-bidi-font-weight:normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>mRNAT7</m:r></span></i></b></m:e></m:d><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>KdegT7</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>T7</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:oMath></m:oMathPara><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;mso-ansi-language:EN-US;mso-fareast-language:
-ZH-TW;mso-bidi-language:AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75"
- style='width:189.75pt;height:36pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image019.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>RBS = binding site strength<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>KdegT7 = degrading constant of T7</span><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US><o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US><o:p>&nbsp;</o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US>The aim of the equation is
-to know the threshold concentration of oxyR to conquer the terminal and when T7
-polymerase can reach the required concentration to activate T7 promoter.<o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US><o:p>&nbsp;</o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><span
-style='font-family:"新細明體","serif"'>‧</span><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US>Equation16:<o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><!--[if gte msEquation 12]><m:oMathPara><m:oMathParaPr><m:jc
-   m:val="left"/></m:oMathParaPr><m:oMath><m:f><m:fPr><span style='font-size:
-.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:
-    "Cambria Math","serif";mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:
-    "Cambria Math";font-weight:bold;mso-bidi-font-weight:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>d</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>PDC</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:num><m:den><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>dt</m:r></span></i></b></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>=</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>RBS</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>×</m:r></span></i></b><m:d><m:dPr><m:begChr m:val="["/><m:endChr
-     m:val="]"/><span style='font-size:10.0pt;mso-ansi-font-size:10.0pt;
-    mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:
-    "Cambria Math";mso-hansi-font-family:"Cambria Math";font-weight:bold;
-    mso-bidi-font-weight:normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>mRNAPDC</m:r></span></i></b></m:e></m:d><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>KdegPDC</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>PDC</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:oMath></m:oMathPara><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;mso-ansi-language:EN-US;mso-fareast-language:
-ZH-TW;mso-bidi-language:AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75"
- style='width:223.5pt;height:36pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image020.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>RBS = binding site strength<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>KdegPDC = degrading constant of PDC<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US><o:p>&nbsp;</o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US>The aim of the equation is
-to know PDC production rate and when it can reach the concentration of ethanol
-pathway equilibrium.<o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US><o:p>&nbsp;</o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><span
-style='font-family:"新細明體","serif"'>‧</span><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US>Equation17:<o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><!--[if gte msEquation 12]><m:oMathPara><m:oMathParaPr><m:jc
-   m:val="left"/></m:oMathParaPr><m:oMath><m:f><m:fPr><span style='font-size:
-.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:
-    "Cambria Math","serif";mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:
-    "Cambria Math";font-weight:bold;mso-bidi-font-weight:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>d</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>ADH</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:num><m:den><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>dt</m:r></span></i></b></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>=</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>RBS</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>×</m:r></span></i></b><m:d><m:dPr><m:begChr m:val="["/><m:endChr
-     m:val="]"/><span style='font-size:10.0pt;mso-ansi-font-size:10.0pt;
-    mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:
-    "Cambria Math";mso-hansi-font-family:"Cambria Math";font-weight:bold;
-    mso-bidi-font-weight:normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>mRNAADH</m:r></span></i></b></m:e></m:d><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>KdegADH</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>ADH</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:oMath></m:oMathPara><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;mso-ansi-language:EN-US;mso-fareast-language:
-ZH-TW;mso-bidi-language:AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75"
- style='width:228.75pt;height:36pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image021.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>RBS = binding site strength<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>KdegADH = degrading constant of ADH<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'><o:p>&nbsp;</o:p></span></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US>The aim of the equation is
-to know ADH production rate and when it can reach the concentration of ethanol
-pathway equilibrium.<o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US><o:p>&nbsp;</o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><span
-style='font-family:"新細明體","serif"'>‧</span><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US>Equation18:<o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><!--[if gte msEquation 12]><m:oMathPara><m:oMath><m:f><m:fPr><span
-    style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><b style='mso-bidi-font-weight:
-    normal'><i style='mso-bidi-font-style:normal'><span lang=EN-US
-    style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>d</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxRAHL</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:num><m:den><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>dt</m:r></span></i></b></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>=</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>KonAHL</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>×</m:r></span></i></b><m:sSup><m:sSupPr><span
-    style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><m:d><m:dPr><m:begChr
-       m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;
-      mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-      mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-      font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;
-      mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>AHL</m:r></span></i></b></m:e></m:d></m:e><m:sup><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>2</m:r></span></i></b></m:sup></m:sSup><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>×</m:r></span></i></b><m:d><m:dPr><m:begChr
-     m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;mso-ansi-font-size:
-.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-    mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-    font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;mso-bidi-font-style:
-    normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b style='mso-bidi-font-weight:
-    normal'><i style='mso-bidi-font-style:normal'><span lang=EN-US
-    style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxR</m:r></span></i></b></m:e></m:d><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>KoffAHL</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>×</m:r></span></i></b><m:d><m:dPr><m:begChr m:val="["/><m:endChr
-     m:val="]"/><span style='font-size:10.0pt;mso-ansi-font-size:10.0pt;
-    mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:
-    "Cambria Math";mso-hansi-font-family:"Cambria Math";font-weight:bold;
-    mso-bidi-font-weight:normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>AHLLuxR</m:r></span></i></b></m:e></m:d></m:oMath></m:oMathPara><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;mso-ansi-language:EN-US;mso-fareast-language:
-ZH-TW;mso-bidi-language:AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75"
- style='width:318.75pt;height:36pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image022.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>KonAHL = 2AHL + LuxR</span><span
-lang=EN-US style='font-size:10.0pt;font-family:Wingdings;mso-ascii-font-family:
-Calibri;mso-ascii-theme-font:minor-latin;mso-hansi-font-family:Calibri;
-mso-hansi-theme-font:minor-latin;mso-char-type:symbol;mso-symbol-font-family:
-Wingdings'><span style='mso-char-type:symbol;mso-symbol-font-family:Wingdings'>&agrave;</span></span><span
-lang=EN-US style='font-size:10.0pt'>(AHL)2/LuxR complex rate constant<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>KoffAHL = (AHL)2/LuxR complex</span><span
-lang=EN-US style='font-size:10.0pt;font-family:Wingdings;mso-ascii-font-family:
-Calibri;mso-ascii-theme-font:minor-latin;mso-hansi-font-family:Calibri;
-mso-hansi-theme-font:minor-latin;mso-char-type:symbol;mso-symbol-font-family:
-Wingdings'><span style='mso-char-type:symbol;mso-symbol-font-family:Wingdings'>&agrave;</span></span><span
-lang=EN-US style='font-size:10.0pt'>2AHL + LuxR rate constant<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US><o:p>&nbsp;</o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US>The aim of the equation is to know (AHL/LuxR)complex production rate
-and when it can reach the concentration to activate LuxR/cI hybrid promoter</span></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US><o:p>&nbsp;</o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><span
-style='font-family:"新細明體","serif"'>‧</span><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US>Equation19:<o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><!--[if gte msEquation 12]><m:oMathPara><m:oMathParaPr><m:jc
-   m:val="left"/></m:oMathParaPr><m:oMath><m:f><m:fPr><span style='font-size:
-.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:
-    "Cambria Math","serif";mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:
-    "Cambria Math";font-weight:bold;mso-bidi-font-weight:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>d</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>kill</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:num><m:den><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>dt</m:r></span></i></b></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>=</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>RBS</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>×</m:r></span></i></b><m:d><m:dPr><m:begChr m:val="["/><m:endChr
-     m:val="]"/><span style='font-size:10.0pt;mso-ansi-font-size:10.0pt;
-    mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:
-    "Cambria Math";mso-hansi-font-family:"Cambria Math";font-weight:bold;
-    mso-bidi-font-weight:normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>mRNAkill</m:r></span></i></b></m:e></m:d><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>Kdegkill</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>kill</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:oMath></m:oMathPara><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;mso-ansi-language:EN-US;mso-fareast-language:
-ZH-TW;mso-bidi-language:AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75"
- style='width:209.25pt;height:36pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image023.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>RBS = binding site strength<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt'>Kdegkill = degrading constant of kill</span><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US><o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US><o:p>&nbsp;</o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US>The aim of the equation is
-to knowkiller protein production rate and when it can reach the effective
-concentration to kill<i style='mso-bidi-font-style:normal'>Nosema</i>.</span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US><o:p>&nbsp;</o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><span
-style='font-family:"新細明體","serif"'>‧</span><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US>Equation20:<o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:16.0pt;mso-char-indent-count:2.0'><!--[if gte msEquation 12]><m:oMathPara><m:oMath><m:f><m:fPr><span
-    style='font-size:8.0pt;mso-ansi-font-size:8.0pt;mso-bidi-font-size:8.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><b style='mso-bidi-font-weight:
-    normal'><span lang=EN-US style='font-size:8.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="b"/></m:rPr>d</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-       m:val="b"/></m:rPr>[</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="b"/></m:rPr>ethanol</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="b"/></m:rPr>]</m:r></span></b></m:num><m:den><b
-    style='mso-bidi-font-weight:normal'><span lang=EN-US style='font-size:8.0pt;
-    font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-       m:val="b"/></m:rPr>dt</m:r></span></b></m:den></m:f><b style='mso-bidi-font-weight:
-  normal'><span lang=EN-US style='font-size:8.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="b"/></m:rPr>=</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="b"/></m:rPr>K</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="b"/><m:nor/></m:rPr>pyruvateacetaldehyde×</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="b"/><m:nor/></m:rPr>Ka</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="b"/><m:nor/></m:rPr>cetaldehydeethanol×</m:r></span></b><m:f><m:fPr><span
-    style='font-size:8.0pt;mso-ansi-font-size:8.0pt;mso-bidi-font-size:8.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><m:sSup><m:sSupPr><span
-      style='font-size:8.0pt;mso-ansi-font-size:8.0pt;mso-bidi-font-size:8.0pt;
-      font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b style='mso-bidi-font-weight:
-      normal'><span lang=EN-US style='font-size:8.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="b"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="b"/></m:rPr>PDC</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="b"/></m:rPr>]</m:r></span></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><span lang=EN-US style='font-size:
-.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-         m:val="b"/></m:rPr>nPDC</m:r></span></b></m:sup></m:sSup></m:num><m:den><m:sSup><m:sSupPr><span
-      style='font-size:8.0pt;mso-ansi-font-size:8.0pt;mso-bidi-font-size:8.0pt;
-      font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b style='mso-bidi-font-weight:
-      normal'><span lang=EN-US style='font-size:8.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="b"/></m:rPr>KdPDC</m:r></span></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:8.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nPDC</m:r></span></i></b></m:sup></m:sSup><b
-    style='mso-bidi-font-weight:normal'><span lang=EN-US style='font-size:8.0pt;
-    font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-       m:val="b"/></m:rPr>+[</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-       m:val="b"/></m:rPr>PDC</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-       m:val="b"/></m:rPr>]</m:r></span></b></m:den></m:f><b style='mso-bidi-font-weight:
-  normal'><span lang=EN-US style='font-size:8.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="b"/></m:rPr> ×</m:r></span></b><m:f><m:fPr><span
-    style='font-size:8.0pt;mso-ansi-font-size:8.0pt;mso-bidi-font-size:8.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><m:sSup><m:sSupPr><span
-      style='font-size:8.0pt;mso-ansi-font-size:8.0pt;mso-bidi-font-size:8.0pt;
-      font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b style='mso-bidi-font-weight:
-      normal'><span lang=EN-US style='font-size:8.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="b"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="b"/></m:rPr>ADH</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="b"/></m:rPr>]</m:r></span></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><span lang=EN-US style='font-size:
-.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-         m:val="b"/></m:rPr>nADH</m:r></span></b></m:sup></m:sSup></m:num><m:den><m:sSup><m:sSupPr><span
-      style='font-size:8.0pt;mso-ansi-font-size:8.0pt;mso-bidi-font-size:8.0pt;
-      font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b style='mso-bidi-font-weight:
-      normal'><span lang=EN-US style='font-size:8.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="b"/></m:rPr>KdADH</m:r></span></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:8.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nADH</m:r></span></i></b></m:sup></m:sSup><b
-    style='mso-bidi-font-weight:normal'><span lang=EN-US style='font-size:8.0pt;
-    font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-       m:val="b"/></m:rPr>+[</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-       m:val="b"/></m:rPr>ADH</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-       m:val="b"/></m:rPr>]</m:r></span></b></m:den></m:f><b style='mso-bidi-font-weight:
-  normal'><span lang=EN-US style='font-size:8.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="b"/></m:rPr> ×</m:r></span></b><m:d><m:dPr><m:begChr
-     m:val="["/><m:endChr m:val="]"/><span style='font-size:8.0pt;mso-ansi-font-size:
-.0pt;mso-bidi-font-size:8.0pt;font-family:"Cambria Math","serif";
-    mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-    font-weight:bold;mso-bidi-font-weight:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-    style='mso-bidi-font-weight:normal'><span lang=EN-US style='font-size:8.0pt;
-    font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-       m:val="b"/></m:rPr>pyruvate</m:r></span></b></m:e></m:d><b
-  style='mso-bidi-font-weight:normal'><span lang=EN-US style='font-size:8.0pt;
-  font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="b"/></m:rPr>-</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="b"/></m:rPr>Km</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="b"/></m:rPr>×</m:r></span></b><m:f><m:fPr><span
-    style='font-size:8.0pt;mso-ansi-font-size:8.0pt;mso-bidi-font-size:8.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><m:sSup><m:sSupPr><span
-      style='font-size:8.0pt;mso-ansi-font-size:8.0pt;mso-bidi-font-size:8.0pt;
-      font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><m:d><m:dPr><m:begChr
-         m:val="["/><m:endChr m:val="]"/><span style='font-size:8.0pt;
-        mso-ansi-font-size:8.0pt;mso-bidi-font-size:8.0pt;font-family:"Cambria Math","serif";
-        mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-        font-weight:bold;mso-bidi-font-weight:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-        style='mso-bidi-font-weight:normal'><span lang=EN-US style='font-size:
-.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-           m:val="b"/></m:rPr>ADH</m:r></span></b></m:e></m:d></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><span lang=EN-US style='font-size:
-.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-         m:val="b"/></m:rPr>nADH</m:r></span></b></m:sup></m:sSup></m:num><m:den><m:sSup><m:sSupPr><span
-      style='font-size:8.0pt;mso-ansi-font-size:8.0pt;mso-bidi-font-size:8.0pt;
-      font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b style='mso-bidi-font-weight:
-      normal'><span lang=EN-US style='font-size:8.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="b"/></m:rPr>KdADH</m:r></span></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:8.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nADH</m:r></span></i></b></m:sup></m:sSup><b
-    style='mso-bidi-font-weight:normal'><span lang=EN-US style='font-size:8.0pt;
-    font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-       m:val="b"/></m:rPr>+</m:r></span></b><m:sSup><m:sSupPr><span
-      style='font-size:8.0pt;mso-ansi-font-size:8.0pt;mso-bidi-font-size:8.0pt;
-      font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><m:d><m:dPr><m:begChr
-         m:val="["/><m:endChr m:val="]"/><span style='font-size:8.0pt;
-        mso-ansi-font-size:8.0pt;mso-bidi-font-size:8.0pt;font-family:"Cambria Math","serif";
-        mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-        font-weight:bold;mso-bidi-font-weight:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-        style='mso-bidi-font-weight:normal'><span lang=EN-US style='font-size:
-.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-           m:val="b"/></m:rPr>ADH</m:r></span></b></m:e></m:d></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><span lang=EN-US style='font-size:
-.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-         m:val="b"/></m:rPr>nADH</m:r></span></b></m:sup></m:sSup></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><span lang=EN-US style='font-size:8.0pt;
-  font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="b"/></m:rPr> ×[</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr><i
-   style='mso-bidi-font-style:normal'>ethanol</i></m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="b"/></m:rPr>]</m:r></span></b></m:oMath></m:oMathPara><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;mso-ansi-language:EN-US;mso-fareast-language:
-ZH-TW;mso-bidi-language:AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75"
- style='width:415.5pt;height:1in'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image024.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US style='font-size:10.0pt;
-font-family:"Cambria Math","serif"'><o:p>&nbsp;</o:p></span></b></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'>Kpyruvateacetaldehyde=
-pyruvate</span><span lang=EN-US style='font-size:10.0pt;font-family:Wingdings;
-mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-mso-char-type:symbol;mso-symbol-font-family:Wingdings'><span style='mso-char-type:
-symbol;mso-symbol-font-family:Wingdings'>&agrave;</span></span><span lang=EN-US
-style='font-size:10.0pt;font-family:"Cambria Math","serif"'>acetaldehyde
-reaction rate constant<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'>Kacetaldehydeethanol=
-acetaldehyde </span><span lang=EN-US style='font-size:10.0pt;font-family:Wingdings;
-mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-mso-char-type:symbol;mso-symbol-font-family:Wingdings'><span style='mso-char-type:
-symbol;mso-symbol-font-family:Wingdings'>&agrave;</span></span><span lang=EN-US
-style='font-size:10.0pt;font-family:"Cambria Math","serif"'> ethanol reaction
-rate constant<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'>K</span><span
-lang=EN-US style='font-size:8.0pt;font-family:"Cambria Math","serif"'>m </span><span
-lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'>=
-ethanol </span><span lang=EN-US style='font-size:10.0pt;font-family:Wingdings;
-mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-mso-char-type:symbol;mso-symbol-font-family:Wingdings'><span style='mso-char-type:
-symbol;mso-symbol-font-family:Wingdings'>&agrave;</span></span><span lang=EN-US
-style='font-size:10.0pt;font-family:"Cambria Math","serif"'>acetaldehyde
-reaction rate constant<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'>KdPDC = dissociation
-constant of PDC<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'>KdADH = dissociation
-constant of ADH<o:p></o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><o:p>&nbsp;</o:p></span></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US>The aim of the equation is to know ethanol production rate and when
-it can reach the concentration to kill the spores of NosemaCeranae.</span></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US><o:p>&nbsp;</o:p></span></p>
-<p class=MsoNormal align=center style='text-align:center;text-indent:32.05pt;
-mso-char-indent-count:2.0'><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:16.0pt'>Explanation<o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US><span style='mso-tab-count:
-'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; </span><o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><!--[if gte msEquation 12]><m:oMathPara><m:oMathParaPr><m:jc
-   m:val="left"/></m:oMathParaPr><m:oMath><m:f><m:fPr><span style='font-size:
-.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:
-    "Cambria Math","serif";mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:
-    "Cambria Math";font-weight:bold;mso-bidi-font-weight:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>d</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>mRNACI</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:num><m:den><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>dt</m:r></span></i></b></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>=</m:r></span></i></b><m:f><m:fPr><span
-    style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>1</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r></span></i></b><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>LacI</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLacI</m:r></span></i></b></m:sup></m:sSup></m:num><m:den><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>KdLacI</m:r></span></i></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLacI</m:r></span></i></b></m:sup></m:sSup><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r></span></i></b><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>LacI</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLacI</m:r></span></i></b></m:sup></m:sSup></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>×</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>PoPSpLac</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>×</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>N</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>/</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>V</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>kdegmRNA</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>×[</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>mRNACI</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>]</m:r></span></i></b></m:oMath></m:oMathPara><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;mso-ansi-language:EN-US;mso-fareast-language:
-ZH-TW;mso-bidi-language:AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75"
- style='width:399.75pt;height:36pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image005.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US><o:p>&nbsp;</o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US>In this equation, </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>PoPSpLac</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:48pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image025.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><span lang=EN-US><span
-style='mso-spacerun:yes'>&nbsp;</span>represents the promoter strength of LacI
-promoter, which is measured by the rate of RNApolymerase binding to the
-starting site of DNA transcription; </span><!--[if gte msEquation 12]><m:oMath><m:f><m:fPr><span
-   style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-   font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-   mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-   normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><b
-   style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-   lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="bi"/></m:rPr>1</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-      m:val="bi"/></m:rPr>-</m:r></span></i></b><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>LacI</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLacI</m:r></span></i></b></m:sup></m:sSup></m:num><m:den><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>KdLacI</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLacI</m:r></span></i></b></m:sup></m:sSup><b
-   style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-   lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r></span></i></b><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>LacI</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLacI</m:r></span></i></b></m:sup></m:sSup></m:den></m:f></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:14.5pt;mso-text-raise:
--14.5pt;mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:
-AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75" style='width:83.25pt;
- height:36pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image026.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>represents
-the hill effect of repressor LacI to LacI promoter. Because LacI is a
-repressor, the numerator i</span><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'>s </span></b><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>1</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>-</m:r></span></i></b><m:sSup><m:sSupPr><span
-   style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-   font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-   mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-   normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-   style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-   lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-      m:val="bi"/></m:rPr>LacI</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-      m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-   style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-   lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLacI</m:r></span></i></b></m:sup></m:sSup></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:66pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image027.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'>.<o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US style='font-size:10.0pt'><span
-style='mso-tab-count:1'>&nbsp; </span></span></b><span lang=EN-US>For the
-section of the equation, </span><!--[if gte msEquation 12]><m:oMath><m:f><m:fPr><span
-   style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-   font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-   mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-   normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><b
-   style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-   lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="bi"/></m:rPr>1</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-      m:val="bi"/></m:rPr>-</m:r></span></i></b><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>LacI</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLacI</m:r></span></i></b></m:sup></m:sSup></m:num><m:den><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>KdLacI</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLacI</m:r></span></i></b></m:sup></m:sSup><b
-   style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-   lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r></span></i></b><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>LacI</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLacI</m:r></span></i></b></m:sup></m:sSup></m:den></m:f><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>×</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>PoPSpLac</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>×</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>N</m:r><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>/</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>V</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:14.5pt;mso-text-raise:
--14.5pt;mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:
-AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75" style='width:174pt;
- height:36pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image028.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>represents the
-synthesizing rate of </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>mRNACI</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:41.25pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image029.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>under the
-influence of </span><!--[if gte msEquation 12]><m:oMath><b style='mso-bidi-font-weight:
- normal'><i style='mso-bidi-font-style:normal'><span lang=EN-US
- style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>LacI</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:21pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image030.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>and </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>LacI</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:21pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image030.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><span lang=EN-US><span
-style='mso-spacerun:yes'>&nbsp;</span>promoter; </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>kdegmRNA</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>×</m:r></span></i></b><m:d><m:dPr><m:begChr m:val="["/><m:endChr
-    m:val="]"/><span style='font-size:10.0pt;mso-ansi-font-size:10.0pt;
-   mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:
-   "Cambria Math";mso-hansi-font-family:"Cambria Math";font-weight:bold;
-   mso-bidi-font-weight:normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-   style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-   lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="bi"/></m:rPr>mRNACI</m:r></span></i></b></m:e></m:d></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:122.25pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image031.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>represents
-the degrading rate of </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>mRNACI</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:41.25pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image029.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0;
-tab-stops:58.75pt'><b style='mso-bidi-font-weight:normal'><span lang=EN-US
-style='font-size:10.0pt'><span style='mso-tab-count:1'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; </span><o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0;
-tab-stops:58.75pt'><!--[if gte msEquation 12]><m:oMathPara><m:oMath><m:f><m:fPr><span
-    style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><b style='mso-bidi-font-weight:
-    normal'><i style='mso-bidi-font-style:normal'><span lang=EN-US
-    style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>d</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>CI</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:num><m:den><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>dt</m:r></span></i></b></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>=</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>RBS</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>×</m:r></span></i></b><m:d><m:dPr><m:begChr m:val="["/><m:endChr
-     m:val="]"/><span style='font-size:10.0pt;mso-ansi-font-size:10.0pt;
-    mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:
-    "Cambria Math";mso-hansi-font-family:"Cambria Math";font-weight:bold;
-    mso-bidi-font-weight:normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>mRNA&#55349;&#56452;I</m:r></span></i></b></m:e></m:d><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>KdegCI</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>CI</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:oMath></m:oMathPara><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;mso-ansi-language:EN-US;mso-fareast-language:
-ZH-TW;mso-bidi-language:AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75"
- style='width:182.25pt;height:36pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image014.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0;
-tab-stops:58.75pt'><b style='mso-bidi-font-weight:normal'><span lang=EN-US
-style='font-size:10.0pt'><span style='mso-tab-count:1'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; </span></span></b><span
-lang=EN-US>In this equation,</span><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'> </span></b><b style='mso-bidi-font-weight:
-normal'><i style='mso-bidi-font-style:normal'><span lang=EN-US
-style='font-size:10.0pt;font-family:"Cambria Math","serif"'>RBS </span></i></b><span
-lang=EN-US>represents ribosome binding site strength, which is the affinity of
-ribosome to the starting site of mRNA.</span></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0;
-tab-stops:58.75pt'><span lang=EN-US><span style='mso-tab-count:1'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; </span>For
-the section of the equation, </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>RBS</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>×</m:r></span></i></b><m:d><m:dPr><m:begChr m:val="["/><m:endChr
-    m:val="]"/><span style='font-size:10.0pt;mso-ansi-font-size:10.0pt;
-   mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:
-   "Cambria Math";mso-hansi-font-family:"Cambria Math";font-weight:bold;
-   mso-bidi-font-weight:normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-   style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-   lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="bi"/></m:rPr>mRNAcI</m:r></span></i></b></m:e></m:d></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:78pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image032.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>represents the
-synthesizing rate of </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>CI</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:10.5pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image033.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><span lang=EN-US>; </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>kdegCI</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>×</m:r></span></i></b><m:d><m:dPr><m:begChr m:val="["/><m:endChr
-    m:val="]"/><span style='font-size:10.0pt;mso-ansi-font-size:10.0pt;
-   mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:
-   "Cambria Math";mso-hansi-font-family:"Cambria Math";font-weight:bold;
-   mso-bidi-font-weight:normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-   style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-   lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="bi"/></m:rPr>CI</m:r></span></i></b></m:e></m:d></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:1in;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image034.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>represents
-the degrading rate of CI.</span><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0;
-tab-stops:58.75pt'><b style='mso-bidi-font-weight:normal'><span lang=EN-US
-style='font-size:10.0pt'><span style='mso-tab-count:1'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; </span></span></b><span
-lang=EN-US>Since LuxCI hybrid promoter is CI dominant, the presence of CI block
-the promoter and kill protein is not produced. This situation happens when
-there is no <i style='mso-bidi-font-style:normal'>Nosema</i> in bees.</span></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0;
-tab-stops:58.75pt'><span lang=EN-US><span
-style='mso-spacerun:yes'>&nbsp;</span></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><!--[if gte msEquation 12]><m:oMathPara><m:oMath><m:f><m:fPr><span
-    style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><b style='mso-bidi-font-weight:
-    normal'><i style='mso-bidi-font-style:normal'><span lang=EN-US
-    style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>d</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>mRNALacI</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:num><m:den><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>dt</m:r></span></i></b></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>=</m:r></span></i></b><m:f><m:fPr><span
-    style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>ROSoxyR</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nROSoxyR</m:r></span></i></b></m:sup></m:sSup></m:num><m:den><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>KdROSoxyR</m:r></span></i></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nROSoxyR</m:r></span></i></b></m:sup></m:sSup><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r></span></i></b><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>ROSoxyR</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nROSoxyR</m:r></span></i></b></m:sup></m:sSup></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>×</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>PoPStrxC</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>×</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>N</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>/</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>V</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>kdegmRNA</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>×[</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>mRNAlacI</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>]</m:r></span></i></b></m:oMath></m:oMathPara><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;mso-ansi-language:EN-US;mso-fareast-language:
-ZH-TW;mso-bidi-language:AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75"
- style='width:415.5pt;height:54pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image006.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US><o:p>&nbsp;</o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US>In this equation, </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>PoPStrxC</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:46.5pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image035.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><span lang=EN-US><span
-style='mso-spacerun:yes'>&nbsp;</span>represents the promoter strength of
-promotertrxC, which is measured by the rate of RNApolymerase binding to the
-starting site of DNA transcription; </span><!--[if gte msEquation 12]><m:oMath><m:f><m:fPr><span
-   style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-   font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-   mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-   normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>ROSoxyR</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nROSoxyR</m:r></span></i></b></m:sup></m:sSup></m:num><m:den><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>KdROSoxyR</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nROSoxyR</m:r></span></i></b></m:sup></m:sSup><b
-   style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-   lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r></span></i></b><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>ROSoxyR</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nROSoxyR</m:r></span></i></b></m:sup></m:sSup></m:den></m:f></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:14.5pt;mso-text-raise:
--14.5pt;mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:
-AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75" style='width:2in;height:36pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image036.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>represents
-the hill effect of activator ROSoxyR to trxCpromoter.</span><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US style='font-size:10.0pt'><span
-style='mso-tab-count:1'>&nbsp; </span><o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US>For the section of the equation, </span><!--[if gte msEquation 12]><m:oMath><m:f><m:fPr><span
-   style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-   font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-   mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-   normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>ROSoxyR</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nROSoxyR</m:r></span></i></b></m:sup></m:sSup></m:num><m:den><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>KdROSoxyR</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nROSoxyR</m:r></span></i></b></m:sup></m:sSup><b
-   style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-   lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r></span></i></b><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>ROSoxyR</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nROSoxyR</m:r></span></i></b></m:sup></m:sSup></m:den></m:f><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>×</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>PoPStrxC</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>×</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>N</m:r><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>/</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>V</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:14.5pt;mso-text-raise:
--14.5pt;mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:
-AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75" style='width:232.5pt;
- height:36pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image037.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>represents the
-synthesizing rate of </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>mR&#55349;&#56437;ALacI</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:51.75pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image038.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>under the
-influence of activator </span><!--[if gte msEquation 12]><m:oMath><span
- lang=EN-US style='font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="p"/></m:rPr>ROSoxyR</m:r></span></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:4.5pt;mso-text-raise:-4.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:46.5pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image039.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><span lang=EN-US><span
-style='mso-spacerun:yes'>&nbsp;</span>complex and trxC promoter; </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>kdegmRNA</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>×[</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>mRNAlacI</m:r><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:131.25pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image040.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>represents
-the degrading rate of </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>mRNALacI</m:r><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>.</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:54pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image041.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US><o:p>&nbsp;</o:p></span></b></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><!--[if gte msEquation 12]><m:oMathPara><m:oMath><m:f><m:fPr><span
-    style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><b style='mso-bidi-font-weight:
-    normal'><i style='mso-bidi-font-style:normal'><span lang=EN-US
-    style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>d</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>LacI</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:num><m:den><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>dt</m:r></span></i></b></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>=</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>RBS</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>×</m:r></span></i></b><m:d><m:dPr><m:begChr m:val="["/><m:endChr
-     m:val="]"/><span style='font-size:10.0pt;mso-ansi-font-size:10.0pt;
-    mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:
-    "Cambria Math";mso-hansi-font-family:"Cambria Math";font-weight:bold;
-    mso-bidi-font-weight:normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>mRNALacI</m:r></span></i></b></m:e></m:d><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>KdegLacI</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>LacI</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:oMath></m:oMathPara><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;mso-ansi-language:EN-US;mso-fareast-language:
-ZH-TW;mso-bidi-language:AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75"
- style='width:225.75pt;height:36pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image042.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US><o:p>&nbsp;</o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0;
-tab-stops:58.75pt'><span lang=EN-US>In this equation,</span><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US style='font-size:10.0pt'> </span></b><b
-style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'>RBS </span></i></b><span
-lang=EN-US>represents ribosome binding site strength, which is the affinity of
-ribosome to the starting site of mRNA.</span></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0;
-tab-stops:58.75pt'><span lang=EN-US>For the section of the equation, </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>RBS</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>×</m:r></span></i></b><m:d><m:dPr><m:begChr m:val="["/><m:endChr
-    m:val="]"/><span style='font-size:10.0pt;mso-ansi-font-size:10.0pt;
-   mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:
-   "Cambria Math";mso-hansi-font-family:"Cambria Math";font-weight:bold;
-   mso-bidi-font-weight:normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-   style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-   lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="bi"/></m:rPr>mRNALacI</m:r></span></i></b></m:e></m:d></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:90pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image043.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>represents the
-synthesizing rate of </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>LacI</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:21pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image030.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><span lang=EN-US>; </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>KdegCI</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>LacI</m:r><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:72.75pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image044.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>represents
-the degrading rate of </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>LacI</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:21pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image030.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>.</span><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US style='font-size:10.0pt'><o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0;
-tab-stops:34.5pt'><!--[if gte msEquation 12]><m:oMath><b style='mso-bidi-font-weight:
- normal'><i style='mso-bidi-font-style:normal'><span lang=EN-US
- style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>LacI</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:21pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image030.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><span lang=EN-US><span
-style='mso-spacerun:yes'>&nbsp;</span>will repress pLac promoter, which leads
-to no production of</span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr> </m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>CI</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:12.75pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image045.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><span lang=EN-US>. Without </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>CI</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:10.5pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image033.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><span lang=EN-US>, LuxCI hybrid promoter will no
-longer be repressed, and kill protein can thus be generated. This situation
-happens when Nosema exists and the sensor promoter is turned on.</span></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0;
-tab-stops:58.75pt'><span lang=EN-US><o:p>&nbsp;</o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><!--[if gte msEquation 12]><m:oMathPara><m:oMath><m:f><m:fPr><span
-    style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><b style='mso-bidi-font-weight:
-    normal'><span lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="b"/></m:rPr>d</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-       m:val="b"/></m:rPr>[</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="b"/></m:rPr>mRNA</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="b"/><m:nor/></m:rPr>oxyR</m:r></span></b><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="p"/></m:rPr>]</m:r></span></m:num><m:den><b
-    style='mso-bidi-font-weight:normal'><span lang=EN-US style='font-size:10.0pt;
-    font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-       m:val="b"/></m:rPr>dt</m:r></span></b></m:den></m:f><b style='mso-bidi-font-weight:
-  normal'><span lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="b"/></m:rPr>=</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="b"/></m:rPr>PoPSconstitutive</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="b"/></m:rPr>×</m:r></span></b><m:f><m:fPr><span style='font-size:
-.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:
-    "Cambria Math","serif";mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:
-    "Cambria Math";font-weight:bold;mso-bidi-font-weight:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><b
-    style='mso-bidi-font-weight:normal'><span lang=EN-US style='font-size:10.0pt;
-    font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-       m:val="b"/></m:rPr>N</m:r></span></b></m:num><m:den><b style='mso-bidi-font-weight:
-    normal'><span lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="b"/></m:rPr>V</m:r></span></b></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><span lang=EN-US style='font-size:10.0pt;
-  font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="b"/></m:rPr>-</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="b"/></m:rPr>KdegmRNA</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="b"/></m:rPr>[</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="b"/></m:rPr>mRNAoxyR</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="b"/></m:rPr>]</m:r></span></b></m:oMath></m:oMathPara><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;mso-ansi-language:EN-US;mso-fareast-language:
-ZH-TW;mso-bidi-language:AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75"
- style='width:300.75pt;height:36pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image046.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US><o:p>&nbsp;</o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US>In this equation,</span><!--[if gte msEquation 12]><m:oMath><span
- lang=EN-US style='font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="p"/></m:rPr> </m:r></span><b style='mso-bidi-font-weight:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="b"/></m:rPr>PoPSconstitutive</m:r></span></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:4.5pt;mso-text-raise:-4.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:83.25pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image047.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><span lang=EN-US><span
-style='mso-spacerun:yes'>&nbsp;</span>represents the promoter strength of the
-constitutive promoter J23102, which is measured by the rate of RNApolymerase
-binding to the starting site of DNA transcription.</span></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US>For the section of the equation, </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><span lang=EN-US style='font-size:10.0pt;
- font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="b"/></m:rPr>PoPSconstitutive</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="b"/></m:rPr>×</m:r></span></b><m:f><m:fPr><span style='font-size:
-.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-   mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-   font-weight:bold;mso-bidi-font-weight:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><b
-   style='mso-bidi-font-weight:normal'><span lang=EN-US style='font-size:10.0pt;
-   font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-      m:val="b"/></m:rPr>N</m:r></span></b></m:num><m:den><b style='mso-bidi-font-weight:
-   normal'><span lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="b"/></m:rPr>V</m:r></span></b></m:den></m:f></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:96.75pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image048.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>represents
-the synthesizing rate of </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><span lang=EN-US style='font-size:10.0pt;
- font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="b"/></m:rPr>mRNA</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="b"/><m:nor/></m:rPr>oxyR</m:r></span></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:50.25pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image049.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'>;</span></b><span lang=EN-US> </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><span lang=EN-US style='font-size:10.0pt;
- font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="b"/></m:rPr>-</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="b"/></m:rPr>KdegmRNA</m:r><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="b"/></m:rPr>[</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="b"/></m:rPr>mRNAoxyR</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="b"/></m:rPr>]</m:r></span></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:120.75pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image050.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>represents
-the degrading rate of </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><span lang=EN-US style='font-size:10.0pt;
- font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="b"/></m:rPr>mRNA</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="b"/><m:nor/></m:rPr>oxyR</m:r></span></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:50.25pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image049.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'>.<o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US><o:p>&nbsp;</o:p></span></b></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><!--[if gte msEquation 12]><m:oMathPara><m:oMath><m:f><m:fPr><span
-    style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><b style='mso-bidi-font-weight:
-    normal'><i style='mso-bidi-font-style:normal'><span lang=EN-US
-    style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>d</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>mRNALuxI</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:num><m:den><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>dt</m:r></span></i></b></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>=</m:r></span></i></b><m:f><m:fPr><span
-    style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>ROSoxyR</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nROSoxyR</m:r></span></i></b></m:sup></m:sSup></m:num><m:den><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>KdROSoxyR</m:r></span></i></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nROSoxyR</m:r></span></i></b></m:sup></m:sSup><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r></span></i></b><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>ROSoxyR</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nROSoxyR</m:r></span></i></b></m:sup></m:sSup></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>×</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>PoPStrxC</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>×</m:r></span></i></b><m:f><m:fPr><span
-    style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>N</m:r></span></i></b></m:num><m:den><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>V</m:r></span></i></b></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r></span></i></b><m:f><m:fPr><span
-    style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><m:d><m:dPr><m:begChr
-         m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;
-        mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-        mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-        font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;
-        mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-        style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-        lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-           m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxRAHL</m:r></span></i></b></m:e></m:d></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLuxRAHL</m:r></span></i></b></m:sup></m:sSup></m:num><m:den><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>KdLuxRAHL</m:r></span></i></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLuxRAHL</m:r></span></i></b></m:sup></m:sSup><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r></span></i></b><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><m:d><m:dPr><m:begChr
-         m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;
-        mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-        mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-        font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;
-        mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-        style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-        lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-           m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxRAHL</m:r></span></i></b></m:e></m:d></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLuxRAHL</m:r></span></i></b></m:sup></m:sSup></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>×(</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>1</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r></span></i></b><m:f><m:fPr><span
-    style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>1</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>cI</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr> </m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>leak</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>ncI</m:r></span></i></b></m:sup></m:sSup></m:num><m:den><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>KdcI</m:r></span></i></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLacI</m:r></span></i></b></m:sup></m:sSup><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r></span></i></b><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><m:d><m:dPr><m:begChr
-         m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;
-        mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-        mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-        font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;
-        mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-        style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-        lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-           m:val="roman"/><m:sty m:val="bi"/></m:rPr>cI</m:r></span></i></b></m:e></m:d></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>ncI</m:r></span></i></b></m:sup></m:sSup></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>)×</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>PoPSLuxcI</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>×</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>N</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>/</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>V</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>kdegmRNA</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>×[</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>mRNAluxI</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>]</m:r></span></i></b></m:oMath></m:oMathPara><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;mso-ansi-language:EN-US;mso-fareast-language:
-ZH-TW;mso-bidi-language:AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75"
- style='width:415.5pt;height:90pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image051.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US><o:p>&nbsp;</o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US>In this equation, </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>PoPStrxC</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:46.5pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image035.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'>,</span></b><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>PoPSLuxcI</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:52.5pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image052.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>represents
-the promoter strength of promoter trxC and </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxcI</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:27pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image053.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>hybrid
-promoter, which is measured by the rate of RNApolymerase binding to the
-starting site of DNA transcription; </span><!--[if gte msEquation 12]><m:oMath><m:f><m:fPr><span
-   style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-   font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-   mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-   normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>ROSoxyR</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nROSoxyR</m:r></span></i></b></m:sup></m:sSup></m:num><m:den><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>KdROSoxyR</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nROSoxyR</m:r></span></i></b></m:sup></m:sSup><b
-   style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-   lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r></span></i></b><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>ROSoxyR</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nROSoxyR</m:r></span></i></b></m:sup></m:sSup></m:den></m:f></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:14.5pt;mso-text-raise:
--14.5pt;mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:
-AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75" style='width:2in;height:36pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image036.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>represents
-the hill effect of activator ROSoxyR complex to trxCpromoter; </span><!--[if gte msEquation 12]><m:oMath><m:f><m:fPr><span
-   style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-   font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-   mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-   normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxRAHL</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLuxRAHL</m:r></span></i></b></m:sup></m:sSup></m:num><m:den><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>KdLuxRAHL</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLuxRAHL</m:r></span></i></b></m:sup></m:sSup><b
-   style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-   lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r></span></i></b><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxRAHL</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLuxRAHL</m:r></span></i></b></m:sup></m:sSup></m:den></m:f></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:14.5pt;mso-text-raise:
--14.5pt;mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:
-AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75" style='width:145.5pt;
- height:36pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image054.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>represents
-the hill effect of activator </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxRAHL</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:45pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image055.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>to </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxcI</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:27pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image053.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>hybrid promoter;
-</span><!--[if gte msEquation 12]><m:oMath><m:f><m:fPr><span style='font-size:
-.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-   mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-   font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;mso-bidi-font-style:
-   normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>1</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>cI</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr> </m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>leak</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>ncI</m:r></span></i></b></m:sup></m:sSup></m:num><m:den><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>K&#55349;&#56453;cI</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLacI</m:r></span></i></b></m:sup></m:sSup><b
-   style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-   lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r></span></i></b><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><m:d><m:dPr><m:begChr
-        m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;
-       mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-       mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-       font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;
-       mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-       style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-       lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-          m:val="roman"/><m:sty m:val="bi"/></m:rPr>cI</m:r></span></i></b></m:e></m:d></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>ncI</m:r></span></i></b></m:sup></m:sSup></m:den></m:f></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:14.5pt;mso-text-raise:
--14.5pt;mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:
-AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75" style='width:60pt;
- height:36pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image056.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>represents
-the hill effect of repressor CI, while </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>(</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>1</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r></span></i></b><m:f><m:fPr><span
-   style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-   font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-   mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-   normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>1</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>cI</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr> </m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>leak</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>ncI</m:r></span></i></b></m:sup></m:sSup></m:num><m:den><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>KdcI</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLacI</m:r></span></i></b></m:sup></m:sSup><b
-   style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-   lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r></span></i></b><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><m:d><m:dPr><m:begChr
-        m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;
-       mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-       mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-       font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;
-       mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-       style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-       lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-          m:val="roman"/><m:sty m:val="bi"/></m:rPr>cI</m:r></span></i></b></m:e></m:d></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>ncI</m:r></span></i></b></m:sup></m:sSup></m:den></m:f><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>)</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:14.5pt;mso-text-raise:
--14.5pt;mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:
-AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75" style='width:86.25pt;
- height:36pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image057.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>takes CI
-leaking into consideration (promoter pLac will not close thoroughly even though
-CI exists).</span></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US><span style='mso-tab-count:1'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; </span>For
-the section of the equation, </span><!--[if gte msEquation 12]><m:oMath><m:f><m:fPr><span
-   style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-   font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-   mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-   normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>ROSoxyR</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nROSoxyR</m:r></span></i></b></m:sup></m:sSup></m:num><m:den><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>KdROSoxyR</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nROSoxyR</m:r></span></i></b></m:sup></m:sSup><b
-   style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-   lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r></span></i></b><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>ROSoxyR</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nROSoxyR</m:r></span></i></b></m:sup></m:sSup></m:den></m:f><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>×</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>PoPStrxC</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>×</m:r></span></i></b><m:f><m:fPr><span
-   style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-   font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-   mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-   normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><b
-   style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-   lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="bi"/></m:rPr>N</m:r></span></i></b></m:num><m:den><b
-   style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-   lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="bi"/></m:rPr>V</m:r></span></i></b></m:den></m:f></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:14.5pt;mso-text-raise:
--14.5pt;mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:
-AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75" style='width:219pt;
- height:36pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image058.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>represents the
-synthesizing rate of </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>mRNALuxI</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:52.5pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image059.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>under the
-influence of activator</span><!--[if gte msEquation 12]><m:oMath><span
- lang=EN-US style='font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="p"/></m:rPr> </m:r></span><b style='mso-bidi-font-weight:normal'><i
- style='mso-bidi-font-style:normal'><span lang=EN-US style='font-size:10.0pt;
- font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>ROSoxyR</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:4.5pt;mso-text-raise:-4.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:47.25pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image060.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>complex and trxC
-promoter; </span><!--[if gte msEquation 12]><m:oMath><m:f><m:fPr><span
-   style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-   font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-   mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-   normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><m:d><m:dPr><m:begChr
-        m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;
-       mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-       mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-       font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;
-       mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-       style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-       lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-          m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxRAHL</m:r></span></i></b></m:e></m:d></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLuxRAHL</m:r></span></i></b></m:sup></m:sSup></m:num><m:den><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>KdLuxRAHL</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLuxRAHL</m:r></span></i></b></m:sup></m:sSup><b
-   style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-   lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r></span></i></b><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><m:d><m:dPr><m:begChr
-        m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;
-       mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-       mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-       font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;
-       mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-       style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-       lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-          m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxRAHL</m:r></span></i></b></m:e></m:d></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLuxRAHL</m:r></span></i></b></m:sup></m:sSup></m:den></m:f><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>×(</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>1</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r></span></i></b><m:f><m:fPr><span
-   style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-   font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-   mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-   normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>1</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>cI</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr> </m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>leak</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>ncI</m:r></span></i></b></m:sup></m:sSup></m:num><m:den><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>KdcI</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLacI</m:r></span></i></b></m:sup></m:sSup><b
-   style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-   lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r></span></i></b><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><m:d><m:dPr><m:begChr
-        m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;
-       mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-       mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-       font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;
-       mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-       style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-       lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-          m:val="roman"/><m:sty m:val="bi"/></m:rPr>cI</m:r></span></i></b></m:e></m:d></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>ncI</m:r></span></i></b></m:sup></m:sSup></m:den></m:f><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>)×</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>PoPSLuxcI</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>×</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>N</m:r><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>/</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>V</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:14.5pt;mso-text-raise:
--14.5pt;mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:
-AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75" style='width:337.5pt;
- height:36pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image061.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>represents the
-synthesizing rate of </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>mRNALuxI</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:52.5pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image059.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>under the influence
-of </span><!--[if gte msEquation 12]><m:oMath><b style='mso-bidi-font-weight:
- normal'><i style='mso-bidi-font-style:normal'><span lang=EN-US
- style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxRAHL</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:45pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image055.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>complex,</span><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US style='font-size:10.0pt'> </span></b><span
-lang=EN-US>CI repression and leaking, and </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxcI</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:27pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image053.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>hybrid
-promoter; </span><!--[if gte msEquation 12]><m:oMath><b style='mso-bidi-font-weight:
- normal'><i style='mso-bidi-font-style:normal'><span lang=EN-US
- style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>kdegmRNA</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>×[</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>mRNAluxI</m:r><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:132pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image062.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><span lang=EN-US>represents the degrading rate of </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>mRNAluxI</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:51pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image063.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US><o:p>&nbsp;</o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><!--[if gte msEquation 12]><m:oMathPara><m:oMath><m:f><m:fPr><span
-    style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><b style='mso-bidi-font-weight:
-    normal'><i style='mso-bidi-font-style:normal'><span lang=EN-US
-    style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>d</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxI</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:num><m:den><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>dt</m:r></span></i></b></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>=</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>RBS</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>×</m:r></span></i></b><m:d><m:dPr><m:begChr m:val="["/><m:endChr
-     m:val="]"/><span style='font-size:10.0pt;mso-ansi-font-size:10.0pt;
-    mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:
-    "Cambria Math";mso-hansi-font-family:"Cambria Math";font-weight:bold;
-    mso-bidi-font-weight:normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>mRNALuxI</m:r></span></i></b></m:e></m:d><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>KAHL</m:r></span></i></b><m:d><m:dPr><m:begChr m:val="["/><m:endChr
-     m:val="]"/><span style='font-size:10.0pt;mso-ansi-font-size:10.0pt;
-    mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:
-    "Cambria Math";mso-hansi-font-family:"Cambria Math";font-weight:bold;
-    mso-bidi-font-weight:normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxI</m:r></span></i></b></m:e></m:d><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>KdegLuxI</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxI</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:oMath></m:oMathPara><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;mso-ansi-language:EN-US;mso-fareast-language:
-ZH-TW;mso-bidi-language:AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75"
- style='width:298.5pt;height:36pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image016.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US style='font-size:10.0pt'><o:p>&nbsp;</o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0;
-tab-stops:58.75pt'><span lang=EN-US><span style='mso-tab-count:1'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; </span>In
-this equation,</span><b style='mso-bidi-font-weight:normal'><span lang=EN-US
-style='font-size:10.0pt'> </span></b><b style='mso-bidi-font-weight:normal'><i
-style='mso-bidi-font-style:normal'><span lang=EN-US style='font-size:10.0pt;
-font-family:"Cambria Math","serif"'>RBS </span></i></b><span lang=EN-US>represents
-ribosome binding site strength, which is the affinity of ribosome to the
-starting site of mRNA; </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>KAHL</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:27.75pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image064.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>represents
-the rate constant of AHL</span><span lang=EN-US style='font-family:Wingdings;
-mso-ascii-font-family:Calibri;mso-ascii-theme-font:minor-latin;mso-hansi-font-family:
-Calibri;mso-hansi-theme-font:minor-latin;mso-char-type:symbol;mso-symbol-font-family:
-Wingdings'><span style='mso-char-type:symbol;mso-symbol-font-family:Wingdings'>&agrave;</span></span><span
-lang=EN-US>LuxI.</span></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0;
-tab-stops:58.75pt'><span lang=EN-US><span style='mso-tab-count:1'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; </span>For
-the section of the equation, </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>RBS</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>×</m:r></span></i></b><m:d><m:dPr><m:begChr m:val="["/><m:endChr
-    m:val="]"/><span style='font-size:10.0pt;mso-ansi-font-size:10.0pt;
-   mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:
-   "Cambria Math";mso-hansi-font-family:"Cambria Math";font-weight:bold;
-   mso-bidi-font-weight:normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-   style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-   lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="bi"/></m:rPr>mRNALuxI</m:r></span></i></b></m:e></m:d></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:91.5pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image065.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>represents the
-synthesizing rate of </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxI</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:22.5pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image066.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><span lang=EN-US>; </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>KAHL</m:r></span></i></b><m:d><m:dPr><m:begChr
-    m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;mso-ansi-font-size:
-.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-   mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-   font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;mso-bidi-font-style:
-   normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b style='mso-bidi-font-weight:
-   normal'><i style='mso-bidi-font-style:normal'><span lang=EN-US
-   style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxI</m:r></span></i></b></m:e></m:d></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:57pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image067.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>represents
-the transforming rate of AHL</span><span lang=EN-US style='font-family:Wingdings;
-mso-ascii-font-family:Calibri;mso-ascii-theme-font:minor-latin;mso-hansi-font-family:
-Calibri;mso-hansi-theme-font:minor-latin;mso-char-type:symbol;mso-symbol-font-family:
-Wingdings'><span style='mso-char-type:symbol;mso-symbol-font-family:Wingdings'>&agrave;</span></span><span
-lang=EN-US>LuxI; </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>KdegLuxI</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxI</m:r><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:85.5pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image068.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>represents
-the degrading rate of </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxI</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:22.5pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image066.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><span lang=EN-US>.</span><b style='mso-bidi-font-weight:
-normal'><span lang=EN-US style='font-size:10.0pt'><o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0;
-tab-stops:58.75pt'><span lang=EN-US><span style='mso-tab-count:1'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; </span>LacI
-will repress pLac promoter, which leads to no production of CI. Without CI,
-LuxCI hybrid promoter will no longer be repressed, and kill protein can thus be
-generated. This situation happens when <i style='mso-bidi-font-style:normal'>Nosema</i>
-exist, and when the sensor promoter is turned on.</span></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US><o:p>&nbsp;</o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><!--[if gte msEquation 12]><m:oMathPara><m:oMath><m:f><m:fPr><span
-    style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><b style='mso-bidi-font-weight:
-    normal'><i style='mso-bidi-font-style:normal'><span lang=EN-US
-    style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>d</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>mRNALuxR</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:num><m:den><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>dt</m:r></span></i></b></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>=</m:r></span></i></b><m:f><m:fPr><span
-    style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>ROSoxyR</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nROSoxyR</m:r></span></i></b></m:sup></m:sSup></m:num><m:den><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>KdROSoxyR</m:r></span></i></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nROSoxyR</m:r></span></i></b></m:sup></m:sSup><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r></span></i></b><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>ROSoxyR</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nROSoxyR</m:r></span></i></b></m:sup></m:sSup></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>×</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>PoPStrxC</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>×</m:r></span></i></b><m:f><m:fPr><span
-    style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>N</m:r></span></i></b></m:num><m:den><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>V</m:r></span></i></b></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r></span></i></b><m:f><m:fPr><span
-    style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><m:d><m:dPr><m:begChr
-         m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;
-        mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-        mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-        font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;
-        mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-        style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-        lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-           m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxRAHL</m:r></span></i></b></m:e></m:d></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLuxRAHL</m:r></span></i></b></m:sup></m:sSup></m:num><m:den><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>KdLuxRAHL</m:r></span></i></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLuxRAHL</m:r></span></i></b></m:sup></m:sSup><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r></span></i></b><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><m:d><m:dPr><m:begChr
-         m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;
-        mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-        mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-        font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;
-        mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-        style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-        lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-           m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxRAHL</m:r></span></i></b></m:e></m:d></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLuxRAHL</m:r></span></i></b></m:sup></m:sSup></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>×(</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>1</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r></span></i></b><m:f><m:fPr><span
-    style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>(</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>1</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>cI</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr> </m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>leak</m:r><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>ncI</m:r></span></i></b></m:sup></m:sSup></m:num><m:den><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>KdcI</m:r></span></i></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLacI</m:r></span></i></b></m:sup></m:sSup><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r></span></i></b><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><m:d><m:dPr><m:begChr
-         m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;
-        mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-        mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-        font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;
-        mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-        style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-        lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-           m:val="roman"/><m:sty m:val="bi"/></m:rPr>cI</m:r></span></i></b></m:e></m:d></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>ncI</m:r></span></i></b></m:sup></m:sSup></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>)×</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>PoPSLuxcI</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>×</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>N</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>/</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>V</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>kdegmRNA</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>×[</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>mRNAluxR</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>]</m:r></span></i></b></m:oMath></m:oMathPara><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;mso-ansi-language:EN-US;mso-fareast-language:
-ZH-TW;mso-bidi-language:AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75"
- style='width:415.5pt;height:90pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image069.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US><o:p>&nbsp;</o:p></span></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US>In this equation, </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>PoPStrxC</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:46.5pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image035.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'>,</span></b><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>PoPSLuxcI</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:52.5pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image052.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>represents
-the promoter strength of promoter trxC and </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxcI</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:27pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image053.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>hybrid
-promoter, which is measured by the rate of RNApolymerase binding to the starting
-site of DNA transcription; </span><!--[if gte msEquation 12]><m:oMath><m:f><m:fPr><span
-   style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-   font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-   mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-   normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>ROSoxyR</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nROSoxyR</m:r></span></i></b></m:sup></m:sSup></m:num><m:den><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>KdROSoxyR</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nROSoxyR</m:r></span></i></b></m:sup></m:sSup><b
-   style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-   lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r></span></i></b><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>ROSoxyR</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nROSoxyR</m:r></span></i></b></m:sup></m:sSup></m:den></m:f></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:14.5pt;mso-text-raise:
--14.5pt;mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:
-AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75" style='width:2in;height:36pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image036.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>represents
-the hill effect of activator ROSoxyR to trxCpromoter; </span><!--[if gte msEquation 12]><m:oMath><m:f><m:fPr><span
-   style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-   font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-   mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-   normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>ROSoxyR</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nROSoxyR</m:r></span></i></b></m:sup></m:sSup></m:num><m:den><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>KdROSoxyR</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nROSo&#55349;&#56473;yR</m:r></span></i></b></m:sup></m:sSup><b
-   style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-   lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r></span></i></b><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>ROSoxyR</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nROSoxyR</m:r></span></i></b></m:sup></m:sSup></m:den></m:f></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:14.5pt;mso-text-raise:
--14.5pt;mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:
-AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75" style='width:2in;height:36pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image036.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>represents
-the hill effect of activator ROSoxyR to trxCpromoter; </span><!--[if gte msEquation 12]><m:oMath><m:f><m:fPr><span
-   style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-   font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-   mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-   normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxRAHL</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLuxRAHL</m:r></span></i></b></m:sup></m:sSup></m:num><m:den><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>KdLuxRAHL</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLuxRAHL</m:r></span></i></b></m:sup></m:sSup><b
-   style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-   lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r></span></i></b><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxRAHL</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLuxRAHL</m:r></span></i></b></m:sup></m:sSup></m:den></m:f></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:14.5pt;mso-text-raise:
--14.5pt;mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:
-AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75" style='width:145.5pt;
- height:36pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image054.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><span lang=EN-US>represents the hill effect of activator
-</span><!--[if gte msEquation 12]><m:oMath><b style='mso-bidi-font-weight:normal'><i
- style='mso-bidi-font-style:normal'><span lang=EN-US style='font-size:10.0pt;
- font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>LuxRAH&#55349;&#56435;</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:45pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image055.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>to </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxcI</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:27pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image053.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>hybrid promoter;
-</span><!--[if gte msEquation 12]><m:oMath><m:f><m:fPr><span style='font-size:
-.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-   mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-   font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;mso-bidi-font-style:
-   normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>1</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>cI</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr> </m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>leak</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>ncI</m:r></span></i></b></m:sup></m:sSup></m:num><m:den><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>KdcI</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLacI</m:r></span></i></b></m:sup></m:sSup><b
-   style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-   lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r></span></i></b><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><m:d><m:dPr><m:begChr
-        m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;
-       mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-       mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-       font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;
-       mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-       style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-       lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-          m:val="roman"/><m:sty m:val="bi"/></m:rPr>cI</m:r></span></i></b></m:e></m:d></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>ncI</m:r></span></i></b></m:sup></m:sSup></m:den></m:f></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:14.5pt;mso-text-raise:
--14.5pt;mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:
-AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75" style='width:60pt;
- height:36pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image056.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>represents
-the hill effect of repressor CI, while </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>(</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>1</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r></span></i></b><m:f><m:fPr><span
-   style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-   font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-   mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-   normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>1</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>cI</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr> </m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>leak</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>ncI</m:r></span></i></b></m:sup></m:sSup></m:num><m:den><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>KdcI</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLacI</m:r></span></i></b></m:sup></m:sSup><b
-   style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-   lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r></span></i></b><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><m:d><m:dPr><m:begChr
-        m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;
-       mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-       mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-       font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;
-       mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-       style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-       lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-          m:val="roman"/><m:sty m:val="bi"/></m:rPr>cI</m:r></span></i></b></m:e></m:d></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>ncI</m:r></span></i></b></m:sup></m:sSup></m:den></m:f><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>)</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:14.5pt;mso-text-raise:
--14.5pt;mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:
-AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75" style='width:86.25pt;
- height:36pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image057.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>takes CI
-leaking into consideration.</span></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US>For the section of the equation, </span><!--[if gte msEquation 12]><m:oMath><m:f><m:fPr><span
-   style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-   font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-   mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-   normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>ROSoxyR</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nROSoxyR</m:r></span></i></b></m:sup></m:sSup></m:num><m:den><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>KdROSoxyR</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nROSoxyR</m:r></span></i></b></m:sup></m:sSup><b
-   style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-   lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r></span></i></b><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>ROSoxyR</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nROSoxyR</m:r></span></i></b></m:sup></m:sSup></m:den></m:f><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>×</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>PoPStrxC</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>×</m:r></span></i></b><m:f><m:fPr><span
-   style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-   font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-   mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-   normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><b
-   style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-   lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="bi"/></m:rPr>N</m:r></span></i></b></m:num><m:den><b
-   style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-   lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="bi"/></m:rPr>V</m:r></span></i></b></m:den></m:f></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:14.5pt;mso-text-raise:
--14.5pt;mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:
-AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75" style='width:219pt;
- height:36pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image058.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>represents the
-synthesizing rate of </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>mRNALuxI</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:52.5pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image059.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>under the
-influence of activator <span style='mso-spacerun:yes'>&nbsp;</span></span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>ROSoxyR</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:44.25pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image070.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>and trxC
-promoter; </span><!--[if gte msEquation 12]><m:oMath><m:f><m:fPr><span
-   style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-   font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-   mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-   normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><m:d><m:dPr><m:begChr
-        m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;
-       mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-       mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-       font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;
-       mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-       style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-       lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-          m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxRAHL</m:r></span></i></b></m:e></m:d></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLuxRAHL</m:r></span></i></b></m:sup></m:sSup></m:num><m:den><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>KdLuxRAHL</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLuxRAHL</m:r></span></i></b></m:sup></m:sSup><b
-   style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-   lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r></span></i></b><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><m:d><m:dPr><m:begChr
-        m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;
-       mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-       mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-       font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;
-       mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-       style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-       lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-          m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxRAHL</m:r></span></i></b></m:e></m:d></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLuxRAHL</m:r></span></i></b></m:sup></m:sSup></m:den></m:f><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>×(</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>1</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r></span></i></b><m:f><m:fPr><span
-   style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-   font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-   mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-   normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>1</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>cI</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr> </m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>leak</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>ncI</m:r></span></i></b></m:sup></m:sSup></m:num><m:den><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>KdcI</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLacI</m:r></span></i></b></m:sup></m:sSup><b
-   style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-   lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r></span></i></b><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><m:d><m:dPr><m:begChr
-        m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;
-       mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-       mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-       font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;
-       mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-       style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-       lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-          m:val="roman"/><m:sty m:val="bi"/></m:rPr>cI</m:r></span></i></b></m:e></m:d></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>ncI</m:r></span></i></b></m:sup></m:sSup></m:den></m:f><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>)×</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>PoPSLuxcI</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>×</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>N</m:r><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>/</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>V</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:14.5pt;mso-text-raise:
--14.5pt;mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:
-AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75" style='width:337.5pt;
- height:36pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image061.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>represents the
-synthesizing rate of </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>mRNALuxR</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:55.5pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image071.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>under the
-influence of </span><!--[if gte msEquation 12]><m:oMath><b style='mso-bidi-font-weight:
- normal'><i style='mso-bidi-font-style:normal'><span lang=EN-US
- style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxRAHL</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:45pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image055.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><span lang=EN-US>CI repression and leaking, and </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxcI</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:27pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image053.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>hybrid
-promoter; </span><!--[if gte msEquation 12]><m:oMath><b style='mso-bidi-font-weight:
- normal'><i style='mso-bidi-font-style:normal'><span lang=EN-US
- style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>kdegmRNA</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>×[</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>mRNALuxR</m:r><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:136.5pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image072.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>represents
-the degrading rate of </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>mRNALuxR</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:55.5pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image071.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US><o:p>&nbsp;</o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><!--[if gte msEquation 12]><m:oMathPara><m:oMath><m:f><m:fPr><span
-    style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><b style='mso-bidi-font-weight:
-    normal'><i style='mso-bidi-font-style:normal'><span lang=EN-US
-    style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>d</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxR</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:num><m:den><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>dt</m:r></span></i></b></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>=</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>RBS</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>×</m:r></span></i></b><m:d><m:dPr><m:begChr m:val="["/><m:endChr
-     m:val="]"/><span style='font-size:10.0pt;mso-ansi-font-size:10.0pt;
-    mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:
-    "Cambria Math";mso-hansi-font-family:"Cambria Math";font-weight:bold;
-    mso-bidi-font-weight:normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>mRNALuxR</m:r></span></i></b></m:e></m:d><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>KmAHL</m:r></span></i></b><m:d><m:dPr><m:begChr m:val="["/><m:endChr
-     m:val="]"/><span style='font-size:10.0pt;mso-ansi-font-size:10.0pt;
-    mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:
-    "Cambria Math";mso-hansi-font-family:"Cambria Math";font-weight:bold;
-    mso-bidi-font-weight:normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>AHL</m:r></span></i></b></m:e></m:d><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>KdegLuxR</m:r></span></i></b><m:d><m:dPr><m:begChr
-     m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;mso-ansi-font-size:
-.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-    mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-    font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;mso-bidi-font-style:
-    normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b style='mso-bidi-font-weight:
-    normal'><i style='mso-bidi-font-style:normal'><span lang=EN-US
-    style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxR</m:r></span></i></b></m:e></m:d><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>KonAHL</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>×</m:r></span></i></b><m:sSup><m:sSupPr><span
-    style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><m:d><m:dPr><m:begChr
-       m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;
-      mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-      mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-      font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;
-      mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>AHL</m:r></span></i></b></m:e></m:d></m:e><m:sup><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>2</m:r></span></i></b></m:sup></m:sSup><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>×</m:r></span></i></b><m:d><m:dPr><m:begChr
-     m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;mso-ansi-font-size:
-.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-    mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-    font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;mso-bidi-font-style:
-    normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b style='mso-bidi-font-weight:
-    normal'><i style='mso-bidi-font-style:normal'><span lang=EN-US
-    style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxR</m:r></span></i></b></m:e></m:d><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>KdegAHL</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>AHL</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:oMath></m:oMathPara><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;mso-ansi-language:EN-US;mso-fareast-language:
-ZH-TW;mso-bidi-language:AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75"
- style='width:415.5pt;height:54pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image017.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US><o:p>&nbsp;</o:p></span></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0;
-tab-stops:58.75pt'><span lang=EN-US>In this equation,</span><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US style='font-size:10.0pt'> </span></b><b
-style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'>RBS </span></i></b><span
-lang=EN-US>represents ribosome binding site strength, which is the affinity of
-ribosome to the starting site of mRNA; </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>KmAHL</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:36.75pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image073.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>represents
-the rate constant of AHL</span><span lang=EN-US style='font-family:Wingdings;
-mso-ascii-font-family:Calibri;mso-ascii-theme-font:minor-latin;mso-hansi-font-family:
-Calibri;mso-hansi-theme-font:minor-latin;mso-char-type:symbol;mso-symbol-font-family:
-Wingdings'><span style='mso-char-type:symbol;mso-symbol-font-family:Wingdings'>&agrave;</span></span><span
-lang=EN-US>LuxI; </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>KonAHL</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:39.75pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image074.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><span lang=EN-US><span
-style='mso-spacerun:yes'>&nbsp;</span>represents the rate constant of 2AHL+LuxR</span><span
-lang=EN-US style='font-family:Wingdings;mso-ascii-font-family:Calibri;
-mso-ascii-theme-font:minor-latin;mso-hansi-font-family:Calibri;mso-hansi-theme-font:
-minor-latin;mso-char-type:symbol;mso-symbol-font-family:Wingdings'><span
-style='mso-char-type:symbol;mso-symbol-font-family:Wingdings'>&agrave;</span></span><span
-lang=EN-US>AHL2LuxR complex.</span></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0;
-tab-stops:58.75pt'><span lang=EN-US>For the section of the equation, </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>RBS</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>×</m:r></span></i></b><m:d><m:dPr><m:begChr m:val="["/><m:endChr
-    m:val="]"/><span style='font-size:10.0pt;mso-ansi-font-size:10.0pt;
-   mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:
-   "Cambria Math";mso-hansi-font-family:"Cambria Math";font-weight:bold;
-   mso-bidi-font-weight:normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-   style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-   lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="bi"/></m:rPr>mRNALuxR</m:r></span></i></b></m:e></m:d></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:93.75pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image075.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>represents the
-synthesizing rate of </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxR</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:24.75pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image076.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><span lang=EN-US>; </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>KmAHL</m:r></span></i></b><m:d><m:dPr><m:begChr m:val="["/><m:endChr
-    m:val="]"/><span style='font-size:10.0pt;mso-ansi-font-size:10.0pt;
-   mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:
-   "Cambria Math";mso-hansi-font-family:"Cambria Math";font-weight:bold;
-   mso-bidi-font-weight:normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-   style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-   lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="bi"/></m:rPr>AHL</m:r></span></i></b></m:e></m:d></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:1in;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image077.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>represents
-the transforming rate of AHL</span><span lang=EN-US style='font-family:Wingdings;
-mso-ascii-font-family:Calibri;mso-ascii-theme-font:minor-latin;mso-hansi-font-family:
-Calibri;mso-hansi-theme-font:minor-latin;mso-char-type:symbol;mso-symbol-font-family:
-Wingdings'><span style='mso-char-type:symbol;mso-symbol-font-family:Wingdings'>&agrave;</span></span><span
-lang=EN-US>LuxI; </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>KdegLuxR</m:r></span></i></b><m:d><m:dPr><m:begChr
-    m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;mso-ansi-font-size:
-.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-   mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-   font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;mso-bidi-font-style:
-   normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b style='mso-bidi-font-weight:
-   normal'><i style='mso-bidi-font-style:normal'><span lang=EN-US
-   style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxR</m:r></span></i></b></m:e></m:d></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:90.75pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image078.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><span lang=EN-US>represents the degrading rate of </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxR</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:24.75pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image076.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'>; </span></b><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><span lang=EN-US style='font-size:10.0pt;
- font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="b"/></m:rPr>-</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr><i
-  style='mso-bidi-font-style:normal'>KonAHL</i></m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr><i style='mso-bidi-font-style:normal'>×</i></m:r></span></b><m:sSup><m:sSupPr><span
-   style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-   font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-   mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-   normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><m:d><m:dPr><m:begChr
-      m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;mso-ansi-font-size:
-.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-     mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-     font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;mso-bidi-font-style:
-     normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b style='mso-bidi-font-weight:
-     normal'><i style='mso-bidi-font-style:normal'><span lang=EN-US
-     style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>AHL</m:r></span></i></b></m:e></m:d></m:e><m:sup><b
-   style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-   lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="bi"/></m:rPr>2</m:r></span></i></b></m:sup></m:sSup><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>×</m:r></span></i></b><m:d><m:dPr><m:begChr
-    m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;mso-ansi-font-size:
-.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-   mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-   font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;mso-bidi-font-style:
-   normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b style='mso-bidi-font-weight:
-   normal'><i style='mso-bidi-font-style:normal'><span lang=EN-US
-   style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxR</m:r></span></i></b></m:e></m:d></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:134.25pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image079.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>represents
-the transforming rate of 2AHL+LuxR to AHL2LuxR complex; </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>KdegLuxI</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>AHL</m:r><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:83.25pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image080.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>represents
-the degrading rate of </span><!--[if gte msEquation 12]><m:oMath><span
- lang=EN-US style='font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="p"/></m:rPr>AHL</m:r></span></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:4.5pt;mso-text-raise:-4.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:22.5pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image081.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><span lang=EN-US>.</span><b style='mso-bidi-font-weight:
-normal'><span lang=EN-US style='font-size:10.0pt'><o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0;
-tab-stops:58.75pt'><b style='mso-bidi-font-weight:normal'><span lang=EN-US
-style='font-size:10.0pt'><o:p>&nbsp;</o:p></span></b></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><!--[if gte msEquation 12]><m:oMathPara><m:oMath><m:f><m:fPr><span
-    style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><b style='mso-bidi-font-weight:
-    normal'><i style='mso-bidi-font-style:normal'><span lang=EN-US
-    style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>d</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>AHL</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:num><m:den><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>dt</m:r></span></i></b></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>=</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>KAHL</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>×</m:r></span></i></b><m:d><m:dPr><m:begChr m:val="["/><m:endChr
-     m:val="]"/><span style='font-size:10.0pt;mso-ansi-font-size:10.0pt;
-    mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:
-    "Cambria Math";mso-hansi-font-family:"Cambria Math";font-weight:bold;
-    mso-bidi-font-weight:normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxI</m:r></span></i></b></m:e></m:d><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>2</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>×</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>KoffAHL</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>×</m:r></span></i></b><m:d><m:dPr><m:begChr
-     m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;mso-ansi-font-size:
-.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-    mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-    font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;mso-bidi-font-style:
-    normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b style='mso-bidi-font-weight:
-    normal'><i style='mso-bidi-font-style:normal'><span lang=EN-US
-    style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>AHLLuxR</m:r></span></i></b></m:e></m:d><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>2</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>×</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>KonAHL</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>×</m:r></span></i></b><m:sSup><m:sSupPr><span
-    style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><m:d><m:dPr><m:begChr
-       m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;
-      mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-      mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-      font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;
-      mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>AHL</m:r></span></i></b></m:e></m:d></m:e><m:sup><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>2</m:r></span></i></b></m:sup></m:sSup><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>×</m:r></span></i></b><m:d><m:dPr><m:begChr
-     m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;mso-ansi-font-size:
-.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-    mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-    font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;mso-bidi-font-style:
-    normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b style='mso-bidi-font-weight:
-    normal'><i style='mso-bidi-font-style:normal'><span lang=EN-US
-    style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxR</m:r></span></i></b></m:e></m:d><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>KdegAHL</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>AHL</m:r><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:oMath></m:oMathPara><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;mso-ansi-language:EN-US;mso-fareast-language:
-ZH-TW;mso-bidi-language:AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75"
- style='width:415.5pt;height:54pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image018.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US style='font-size:10.0pt'><o:p>&nbsp;</o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0;
-tab-stops:58.75pt'><span lang=EN-US>In this equation,</span><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US style='font-size:10.0pt'> </span></b><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>KAHL</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:27.75pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image064.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>represents
-the rate constant of AHL</span><span lang=EN-US style='font-family:Wingdings;
-mso-ascii-font-family:Calibri;mso-ascii-theme-font:minor-latin;mso-hansi-font-family:
-Calibri;mso-hansi-theme-font:minor-latin;mso-char-type:symbol;mso-symbol-font-family:
-Wingdings'><span style='mso-char-type:symbol;mso-symbol-font-family:Wingdings'>&agrave;</span></span><span
-lang=EN-US>LuxI; </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>KoffAHL</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:45pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image082.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>represents
-the rate constant of AHL2LuxR complex </span><span lang=EN-US style='font-family:
-Wingdings;mso-ascii-font-family:Calibri;mso-ascii-theme-font:minor-latin;
-mso-hansi-font-family:Calibri;mso-hansi-theme-font:minor-latin;mso-char-type:
-symbol;mso-symbol-font-family:Wingdings'><span style='mso-char-type:symbol;
-mso-symbol-font-family:Wingdings'>&agrave;</span></span><span lang=EN-US>2AHL+ LuxR,
-while </span><!--[if gte msEquation 12]><m:oMath><b style='mso-bidi-font-weight:
- normal'><i style='mso-bidi-font-style:normal'><span lang=EN-US
- style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>KonAHL</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:39.75pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image074.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><span lang=EN-US><span
-style='mso-spacerun:yes'>&nbsp;</span>represents the reverse rate constant.</span></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0;
-tab-stops:58.75pt'><span lang=EN-US>For the section of the equation, </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>KAHL</m:r></span></i></b><m:d><m:dPr><m:begChr
-    m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;mso-ansi-font-size:
-.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-   mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-   font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;mso-bidi-font-style:
-   normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b style='mso-bidi-font-weight:
-   normal'><i style='mso-bidi-font-style:normal'><span lang=EN-US
-   style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxI</m:r></span></i></b></m:e></m:d></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:57pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image067.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>represents
-the transforming rate of LuxI</span><span lang=EN-US style='font-family:Wingdings;
-mso-ascii-font-family:Calibri;mso-ascii-theme-font:minor-latin;mso-hansi-font-family:
-Calibri;mso-hansi-theme-font:minor-latin;mso-char-type:symbol;mso-symbol-font-family:
-Wingdings'><span style='mso-char-type:symbol;mso-symbol-font-family:Wingdings'>&agrave;</span></span><span
-lang=EN-US>AHL; </span><!--[if gte msEquation 12]><m:oMath><b style='mso-bidi-font-weight:
- normal'><i style='mso-bidi-font-style:normal'><span lang=EN-US
- style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>2</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>×</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>KoffAHL</m:r><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>×</m:r></span></i></b><m:d><m:dPr><m:begChr
-    m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;mso-ansi-font-size:
-.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-   mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-   font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;mso-bidi-font-style:
-   normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b style='mso-bidi-font-weight:
-   normal'><i style='mso-bidi-font-style:normal'><span lang=EN-US
-   style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="bi"/></m:rPr>AHLLuxR</m:r></span></i></b></m:e></m:d></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:126pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image083.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>represents
-the transforming rate of AHL2LuxR complex to AHL and LuxR, the constant 2 means
-that each complex turns into two AHL; </span><!--[if gte msEquation 12]><m:oMath><span
- lang=EN-US style='font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="p"/></m:rPr>-</m:r></span><b style='mso-bidi-font-weight:normal'><i
- style='mso-bidi-font-style:normal'><span lang=EN-US style='font-size:10.0pt;
- font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>2</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>×</m:r><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>KonAHL</m:r><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>×</m:r></span></i></b><m:sSup><m:sSupPr><span
-   style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-   font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-   mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-   normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><m:d><m:dPr><m:begChr
-      m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;mso-ansi-font-size:
-.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-     mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-     font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;mso-bidi-font-style:
-     normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b style='mso-bidi-font-weight:
-     normal'><i style='mso-bidi-font-style:normal'><span lang=EN-US
-     style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>AHL</m:r></span></i></b></m:e></m:d></m:e><m:sup><b
-   style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-   lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="bi"/></m:rPr>2</m:r></span></i></b></m:sup></m:sSup><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>×</m:r></span></i></b><m:d><m:dPr><m:begChr
-    m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;mso-ansi-font-size:
-.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-   mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-   font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;mso-bidi-font-style:
-   normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b style='mso-bidi-font-weight:
-   normal'><i style='mso-bidi-font-style:normal'><span lang=EN-US
-   style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxR</m:r></span></i></b></m:e></m:d></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:4.5pt;mso-text-raise:-4.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:159pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image084.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>represents
-the transforming rate of 2AHL+LuxR to AHL2LuxR complex; </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>KdegLuxI</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxI</m:r><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:85.5pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image068.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>represents
-the degrading rate of </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxI</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:22.5pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image066.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><span lang=EN-US>.</span><b style='mso-bidi-font-weight:
-normal'><span lang=EN-US style='font-size:10.0pt'><o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0;
-tab-stops:58.75pt'><span lang=EN-US>Since </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxI</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:22.5pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image066.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>will
-transform to </span><!--[if gte msEquation 12]><m:oMath><b style='mso-bidi-font-weight:
- normal'><i style='mso-bidi-font-style:normal'><span lang=EN-US
- style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>AHL</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:20.25pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image085.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'>, </span></b><span lang=EN-US>and</span><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US style='font-size:10.0pt'> </span></b><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><span lang=EN-US style='font-size:10.0pt;
- font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="b"/></m:rPr>2</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr><i
-  style='mso-bidi-font-style:normal'>AHL</i></m:r></span></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:26.25pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image086.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>will combine
-to </span><!--[if gte msEquation 12]><m:oMath><span lang=EN-US
- style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="p"/></m:rPr>LuxR</m:r></span></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:21.75pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image087.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><span lang=EN-US><span
-style='mso-spacerun:yes'>&nbsp;</span>to form</span><!--[if gte msEquation 12]><m:oMath><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="p"/></m:rPr> AHL2LuxR</m:r></span></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:48pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image088.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><span lang=EN-US><span
-style='mso-spacerun:yes'>&nbsp;</span>complex. Because</span><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US style='font-size:10.0pt'> </span></b><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>AHL2LuxR</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:51pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image089.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>will then
-bind to LuxCI hybrid promoter and activate kill gene, </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxR</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:24.75pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image076.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>gene, and
-LuxI gene. In this way, kill protein will kill Nosema, while </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxR</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:24.75pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image076.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'>, </span></b><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxI</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:22.5pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image066.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>will trigger
-the positive feedback and enhance the production of kill protein.</span></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0;
-tab-stops:58.75pt'><span lang=EN-US><o:p>&nbsp;</o:p></span></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><!--[if gte msEquation 12]><m:oMathPara><m:oMath><m:f><m:fPr><span
-    style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><b style='mso-bidi-font-weight:
-    normal'><i style='mso-bidi-font-style:normal'><span lang=EN-US
-    style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>d</m:r></span></i></b><m:d><m:dPr><m:begChr
-       m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;
-      mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-      mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-      font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;
-      mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>mRNAkill</m:r></span></i></b></m:e></m:d></m:num><m:den><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>dt</m:r></span></i></b></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>=</m:r></span></i></b><m:f><m:fPr><span
-    style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><m:d><m:dPr><m:begChr
-         m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;
-        mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-        mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-        font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;
-        mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-        style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-        lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-           m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxRAHL</m:r></span></i></b></m:e></m:d></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLuxRAHL</m:r></span></i></b></m:sup></m:sSup></m:num><m:den><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>KdLuxRAHL</m:r></span></i></b></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLuxRAHL</m:r></span></i></b></m:sup></m:sSup><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r></span></i></b><m:sSup><m:sSupPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><m:d><m:dPr><m:begChr
-         m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;
-        mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-        mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-        font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;
-        mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-        style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-        lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-           m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxRAHL</m:r></span></i></b></m:e></m:d></m:e><m:sup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLuxRAHL</m:r></span></i></b></m:sup></m:sSup></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>×</m:r></span></i></b><m:d><m:dPr><span
-    style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>1</m:r><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r></span></i></b><m:f><m:fPr><span
-      style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-      mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-      normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><m:sSup><m:sSupPr><span
-        style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-        mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-        normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-        style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-        lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-           m:val="roman"/><m:sty m:val="bi"/></m:rPr>(</m:r><m:r><m:rPr><m:scr
-           m:val="roman"/><m:sty m:val="bi"/></m:rPr>1</m:r><m:r><m:rPr><m:scr
-           m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr
-           m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-           m:val="roman"/><m:sty m:val="bi"/></m:rPr>cI</m:r><m:r><m:rPr><m:scr
-           m:val="roman"/><m:sty m:val="bi"/></m:rPr> </m:r><m:r><m:rPr><m:scr
-           m:val="roman"/><m:sty m:val="bi"/></m:rPr>leak</m:r><m:r><m:rPr><m:scr
-           m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-        style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-        lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-           m:val="roman"/><m:sty m:val="bi"/></m:rPr>ncI</m:r></span></i></b></m:sup></m:sSup></m:num><m:den><m:sSup><m:sSupPr><span
-        style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-        mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-        normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-        style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-        lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-           m:val="roman"/><m:sty m:val="bi"/></m:rPr>KdcI</m:r></span></i></b></m:e><m:sup><b
-        style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-        lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-           m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLacI</m:r></span></i></b></m:sup></m:sSup><b
-      style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-      lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-         m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r></span></i></b><m:sSup><m:sSupPr><span
-        style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:
-.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-        mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-        normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><m:d><m:dPr><m:begChr
-           m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;
-          mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-          mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-          font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;
-          mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-          style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:
-          normal'><span lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-             m:val="roman"/><m:sty m:val="bi"/></m:rPr>cI</m:r></span></i></b></m:e></m:d></m:e><m:sup><b
-        style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-        lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-           m:val="roman"/><m:sty m:val="bi"/></m:rPr>ncI</m:r></span></i></b></m:sup></m:sSup></m:den></m:f></m:e></m:d><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>×</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>PoPSLuxcI</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>×</m:r></span></i></b><m:f><m:fPr><span
-    style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-    font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-    mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-    normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>N</m:r></span></i></b></m:num><m:den><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>V</m:r></span></i></b></m:den></m:f><b
-  style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-  lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-     m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>kdegmRNA</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-     m:val="bi"/></m:rPr>×</m:r></span></i></b><m:d><m:dPr><m:begChr m:val="["/><m:endChr
-     m:val="]"/><span style='font-size:10.0pt;mso-ansi-font-size:10.0pt;
-    mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";mso-ascii-font-family:
-    "Cambria Math";mso-hansi-font-family:"Cambria Math";font-weight:bold;
-    mso-bidi-font-weight:normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-    style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-    lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-       m:val="roman"/><m:sty m:val="bi"/></m:rPr>mRNAkill</m:r></span></i></b></m:e></m:d></m:oMath></m:oMathPara><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;mso-ansi-language:EN-US;mso-fareast-language:
-ZH-TW;mso-bidi-language:AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75"
- style='width:415.5pt;height:1in'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image090.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:20.0pt;mso-char-indent-count:2.0'><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US style='font-size:10.0pt'><o:p>&nbsp;</o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US>After trxC promoter is turned on by ROSoxyR complex and the
-downstream genes – LacI, LuxI, and LuxR starts to produce, which blocks the CI
-promoter and turns on the LuxCI hybrid promoter. After that, the gene encoded
-with kill protein downstream LuxCI hybrid promoter also begins to transcribe.</span></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US>This equation shows production rate of mRNAkill. </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>PoPSLuxcI</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:52.5pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image052.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>represents
-the promoter strength of promoter trxC and </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>Luxc&#55349;&#56432;</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:27pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image053.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>hybrid
-promoter, which is measured by the rate of RNApolymerase binding to the
-starting site of DNA transcription; </span><!--[if gte msEquation 12]><m:oMath><m:f><m:fPr><span
-   style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-   font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-   mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-   normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxRAHL</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLuxRAHL</m:r></span></i></b></m:sup></m:sSup></m:num><m:den><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>KdLuxRAHL</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLuxRAHL</m:r></span></i></b></m:sup></m:sSup><b
-   style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-   lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r></span></i></b><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxRAHL</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLuxRAHL</m:r></span></i></b></m:sup></m:sSup></m:den></m:f></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:14.5pt;mso-text-raise:
--14.5pt;mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:
-AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75" style='width:145.5pt;
- height:36pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image054.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><span lang=EN-US>represents the hill effect of activator
-</span><!--[if gte msEquation 12]><m:oMath><b style='mso-bidi-font-weight:normal'><i
- style='mso-bidi-font-style:normal'><span lang=EN-US style='font-size:10.0pt;
- font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>LuxRAHL</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:45pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image055.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><span lang=EN-US>to </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxcI</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:27pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image053.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>hybrid promoter;
-</span><!--[if gte msEquation 12]><m:oMath><m:f><m:fPr><span style='font-size:
-.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-   mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-   font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;mso-bidi-font-style:
-   normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>1</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>cI</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr> </m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>leak</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>ncI</m:r></span></i></b></m:sup></m:sSup></m:num><m:den><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>KdcI</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLacI</m:r></span></i></b></m:sup></m:sSup><b
-   style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-   lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r></span></i></b><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><m:d><m:dPr><m:begChr
-        m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;
-       mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-       mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-       font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;
-       mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-       style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-       lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-          m:val="roman"/><m:sty m:val="bi"/></m:rPr>cI</m:r></span></i></b></m:e></m:d></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>ncI</m:r></span></i></b></m:sup></m:sSup></m:den></m:f></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:14.5pt;mso-text-raise:
--14.5pt;mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:
-AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75" style='width:60pt;
- height:36pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image056.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>represents
-the hill effect of repressor CI, while </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>(</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>1</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r></span></i></b><m:f><m:fPr><span
-   style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-   font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-   mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-   normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>1</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>cI</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr> </m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>leak</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>ncI</m:r></span></i></b></m:sup></m:sSup></m:num><m:den><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>KdcI</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLacI</m:r></span></i></b></m:sup></m:sSup><b
-   style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-   lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r></span></i></b><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><m:d><m:dPr><m:begChr
-        m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;
-       mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-       mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-       font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;
-       mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-       style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-       lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-          m:val="roman"/><m:sty m:val="bi"/></m:rPr>cI</m:r></span></i></b></m:e></m:d></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>ncI</m:r></span></i></b></m:sup></m:sSup></m:den></m:f><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>)</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:14.5pt;mso-text-raise:
--14.5pt;mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:
-AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75" style='width:86.25pt;
- height:36pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image057.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>takes CI
-leaking into consideration. </span></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US>For the section of the equation, </span><!--[if gte msEquation 12]><m:oMath><m:f><m:fPr><span
-   style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-   font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-   mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-   normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><m:d><m:dPr><m:begChr
-        m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;
-       mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-       mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-       font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;
-       mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-       style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-       lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-          m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxRAHL</m:r></span></i></b></m:e></m:d></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLuxRAHL</m:r></span></i></b></m:sup></m:sSup></m:num><m:den><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>KdLuxRAHL</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLuxRAHL</m:r></span></i></b></m:sup></m:sSup><b
-   style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-   lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r></span></i></b><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><m:d><m:dPr><m:begChr
-        m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;
-       mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-       mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-       font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;
-       mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-       style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-       lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-          m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxRAHL</m:r></span></i></b></m:e></m:d></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLuxRAHL</m:r></span></i></b></m:sup></m:sSup></m:den></m:f><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>×(</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>1</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r></span></i></b><m:f><m:fPr><span
-   style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-   font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-   mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-   normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:fPr><m:num><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>1</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>[</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>cI</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr> </m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>leak</m:r><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>ncI</m:r></span></i></b></m:sup></m:sSup></m:num><m:den><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>KdcI</m:r></span></i></b></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>nLacI</m:r></span></i></b></m:sup></m:sSup><b
-   style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-   lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-      m:val="roman"/><m:sty m:val="bi"/></m:rPr>+</m:r></span></i></b><m:sSup><m:sSupPr><span
-     style='font-size:10.0pt;mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;
-     font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-     mso-hansi-font-family:"Cambria Math";font-weight:bold;mso-bidi-font-weight:
-     normal;font-style:italic;mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><m:d><m:dPr><m:begChr
-        m:val="["/><m:endChr m:val="]"/><span style='font-size:10.0pt;
-       mso-ansi-font-size:10.0pt;mso-bidi-font-size:10.0pt;font-family:"Cambria Math","serif";
-       mso-ascii-font-family:"Cambria Math";mso-hansi-font-family:"Cambria Math";
-       font-weight:bold;mso-bidi-font-weight:normal;font-style:italic;
-       mso-bidi-font-style:normal'><m:ctrlPr></m:ctrlPr></span></m:dPr><m:e><b
-       style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-       lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-          m:val="roman"/><m:sty m:val="bi"/></m:rPr>cI</m:r></span></i></b></m:e></m:d></m:e><m:sup><b
-     style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
-     lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-        m:val="roman"/><m:sty m:val="bi"/></m:rPr>ncI</m:r></span></i></b></m:sup></m:sSup></m:den></m:f><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>)×</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>PoPSLuxcI</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>×</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>N</m:r><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>/</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>V</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:14.5pt;mso-text-raise:
--14.5pt;mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:
-AR-SA'><v:shape id="_x0000_i1025" type="#_x0000_t75" style='width:337.5pt;
- height:36pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image061.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>represents the
-synthesizing rate of </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>mRNAkill</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:48pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image091.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><span lang=EN-US>under the influence of </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxRAHL</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:45pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image055.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><span lang=EN-US>CI repression and leaking, and </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>LuxcI</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:27pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image053.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>hybrid
-promoter; </span><!--[if gte msEquation 12]><m:oMath><b style='mso-bidi-font-weight:
- normal'><i style='mso-bidi-font-style:normal'><span lang=EN-US
- style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>-</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>kdegmRNA</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="bi"/></m:rPr>×[</m:r><m:r><m:rPr><m:scr m:val="roman"/><m:sty m:val="bi"/></m:rPr>mRNALuxR</m:r><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>]</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:136.5pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image072.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'><span
-style='mso-spacerun:yes'>&nbsp;</span></span></b><span lang=EN-US>represents
-the degrading rate of </span><!--[if gte msEquation 12]><m:oMath><b
- style='mso-bidi-font-weight:normal'><i style='mso-bidi-font-style:normal'><span
- lang=EN-US style='font-size:10.0pt;font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr
-    m:val="roman"/><m:sty m:val="bi"/></m:rPr>mRNAkill</m:r></span></i></b></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:5.5pt;mso-text-raise:-5.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:48pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image091.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:10.0pt'>.<o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US><o:p>&nbsp;</o:p></span></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US>As for explanations of equation7, 8, 9, 15, 16, 17, 20, please see
-the ethanol wiki for more information.</span></p>
-<p class=MsoNormal style='text-indent:24.0pt;mso-char-indent-count:2.0'><span
-lang=EN-US><o:p>&nbsp;</o:p></span></p>
-<p class=MsoNormal align=center style='text-align:center;text-indent:32.05pt;
-mso-char-indent-count:2.0'><b style='mso-bidi-font-weight:normal'><span
-lang=EN-US style='font-size:16.0pt'>Result:<o:p></o:p></span></b></p>
-<p class=MsoNormal style='text-indent:24.0pt'><span lang=EN-US
-style='mso-no-proof:yes'><v:shape id="圖片_x0020_3" o:spid="_x0000_i1026" type="#_x0000_t75"
- style='width:414.75pt;height:323.25pt;visibility:visible;mso-wrap-style:square'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image092.jpg" o:title=""/>
-</v:shape></span></p>
-<p class=MsoNormal style='text-indent:24.0pt'><span lang=EN-US>After <i
-style='mso-bidi-font-style:normal'>Nosema</i> invasion (t=0), concentration of
-kill protein will reach its constant level, which is </span><!--[if gte msEquation 12]><m:oMath><span
- lang=EN-US style='font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="p"/></m:rPr>6.5×</m:r></span><m:sSup><m:sSupPr><span
-   style='font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-   mso-hansi-font-family:"Cambria Math"'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><i
-   style='mso-bidi-font-style:normal'><span lang=EN-US style='font-family:"Cambria Math","serif"'><m:r>10</m:r></span></i></m:e><m:sup><i
-   style='mso-bidi-font-style:normal'><span lang=EN-US style='font-family:"Cambria Math","serif"'><m:r>-</m:r><m:r>9</m:r></span></i></m:sup></m:sSup></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:4.5pt;mso-text-raise:-4.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:54pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image093.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><span lang=EN-US>. The effective concentration of
-kill protein to kill <i style='mso-bidi-font-style:normal'>Nosema</i> is </span><!--[if gte msEquation 12]><m:oMath><span
- lang=EN-US style='font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="p"/></m:rPr>6.7×</m:r></span><m:sSup><m:sSupPr><span
-   style='font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-   mso-hansi-font-family:"Cambria Math"'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><i
-   style='mso-bidi-font-style:normal'><span lang=EN-US style='font-family:"Cambria Math","serif"'><m:r>10</m:r></span></i></m:e><m:sup><i
-   style='mso-bidi-font-style:normal'><span lang=EN-US style='font-family:"Cambria Math","serif"'><m:r>-</m:r><m:r>10</m:r></span></i></m:sup></m:sSup><i
- style='mso-bidi-font-style:normal'><span lang=EN-US style='font-family:"Cambria Math","serif"'><m:r>M</m:r></span></i></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:4.5pt;mso-text-raise:-4.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:69.75pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image094.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><span lang=EN-US><span
-style='mso-spacerun:yes'>&nbsp;</span>M, which is near the level we have
-modeled. Besides, the time to reach this concentration is 24 hours after <i
-style='mso-bidi-font-style:normal'>Nosema</i> invasion. Since three days after
-Nosema invasion, bees will start to spread Nosema, the constant level of kill
-protein (which is a little higher than the effective one)and the time it needs
-to reach this level (which is a little bit shorter than )shows that Bee. Coli
-can save the bees timely.</span></p>
-<p class=MsoNormal style='text-indent:24.0pt'><span lang=EN-US
-style='mso-no-proof:yes'><v:shape id="圖片_x0020_7" o:spid="_x0000_i1025" type="#_x0000_t75"
- style='width:414.75pt;height:323.25pt;visibility:visible;mso-wrap-style:square'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image095.jpg" o:title=""/>
-</v:shape></span></p>
-<p class=MsoNormal style='text-indent:24.0pt'><span lang=EN-US>Similarly, the
-effective concentration of ethanol to kill bees is </span><!--[if gte msEquation 12]><m:oMath><span
- lang=EN-US style='font-family:"Cambria Math","serif"'><m:r><m:rPr><m:scr m:val="roman"/><m:sty
-    m:val="p"/></m:rPr>2.4×</m:r></span><m:sSup><m:sSupPr><span
-   style='font-family:"Cambria Math","serif";mso-ascii-font-family:"Cambria Math";
-   mso-hansi-font-family:"Cambria Math"'><m:ctrlPr></m:ctrlPr></span></m:sSupPr><m:e><i
-   style='mso-bidi-font-style:normal'><span lang=EN-US style='font-family:"Cambria Math","serif"'><m:r>10</m:r></span></i></m:e><m:sup><i
-   style='mso-bidi-font-style:normal'><span lang=EN-US style='font-family:"Cambria Math","serif"'><m:r>-</m:r><m:r>6</m:r></span></i></m:sup></m:sSup></m:oMath><![endif]--><![if !msEquation]><span
-lang=EN-US style='font-size:12.0pt;mso-bidi-font-size:11.0pt;font-family:"Calibri","sans-serif";
-mso-ascii-theme-font:minor-latin;mso-fareast-font-family:新細明體;mso-fareast-theme-font:
-minor-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman";
-mso-bidi-theme-font:minor-bidi;position:relative;top:4.5pt;mso-text-raise:-4.5pt;
-mso-ansi-language:EN-US;mso-fareast-language:ZH-TW;mso-bidi-language:AR-SA'><v:shape
- id="_x0000_i1025" type="#_x0000_t75" style='width:54.75pt;height:18pt'>
- <v:imagedata src="main%20part%20wiki%20(1)new.files/image096.png" o:title=""
-  chromakey="white"/>
-</v:shape></span><![endif]><span lang=EN-US>M and the time to reach this
-concentration is 72 hours after <i style='mso-bidi-font-style:normal'>Nosema</i>
-invasion. Since kill protein will kick on two days after <i style='mso-bidi-font-style:
-normal'>Nosema</i> invasion, the open time of ethanol (four days after <i
-style='mso-bidi-font-style:normal'>Nosema</i> invasion) is what we desired. That
-is, because ethanol is the last end of preventing <i style='mso-bidi-font-style:
-normal'>Nosema</i> from spreading (it kills the infected bees as well), we want
-the open time of ethanol to be later than kill protein open time. </span></p>
-<p class=MsoNormal><span lang=EN-US><span style='mso-tab-count:1'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; </span>The
-benefits of our circuit are that the dissociation constant of T7 (KdT7) is small,
-which means it is sensitive (will swiftly open right after T7 polymerase
-reaches threshold) and that we use positive feedback to attain the goal of open
-this device like a switch. </span></p>
-<p class=MsoNormal align=center style='text-align:center;text-indent:24.0pt'><b
-style='mso-bidi-font-weight:normal'><span lang=EN-US style='font-size:16.0pt'>Parameter:<o:p></o:p></span></b></p>
-<table class=MsoTableGrid border=1 cellspacing=0 cellpadding=0 width=661
- style='width:496.0pt;border-collapse:collapse;border:none;mso-border-alt:solid windowtext .5pt;
- mso-yfti-tbllook:1184;mso-padding-alt:0cm 5.4pt 0cm 5.4pt'>
- <tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes'>
-  <td width=92 valign=top style='width:69.2pt;border:solid windowtext 1.0pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><b style='mso-bidi-font-weight:normal'><span lang=EN-US>Model<o:p></o:p></span></b></p>
-  </td>
-  <td width=85 valign=top style='width:63.8pt;border:solid windowtext 1.0pt;
-  border-left:none;mso-border-left-alt:solid windowtext .5pt;mso-border-alt:
-  solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><b style='mso-bidi-font-weight:normal'><span lang=EN-US>Parameter<o:p></o:p></span></b></p>
-  </td>
-  <td width=136 valign=top style='width:102.1pt;border:solid windowtext 1.0pt;
-  border-left:none;mso-border-left-alt:solid windowtext .5pt;mso-border-alt:
-  solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><b style='mso-bidi-font-weight:normal'><span lang=EN-US>Description<o:p></o:p></span></b></p>
-  <p class=MsoNormal><b style='mso-bidi-font-weight:normal'><span lang=EN-US><o:p>&nbsp;</o:p></span></b></p>
-  </td>
-  <td width=102 valign=top style='width:76.6pt;border:solid windowtext 1.0pt;
-  border-left:none;mso-border-left-alt:solid windowtext .5pt;mso-border-alt:
-  solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><b style='mso-bidi-font-weight:normal'><span lang=EN-US>value<o:p></o:p></span></b></p>
-  </td>
-  <td width=57 valign=top style='width:42.55pt;border:solid windowtext 1.0pt;
-  border-left:none;mso-border-left-alt:solid windowtext .5pt;mso-border-alt:
-  solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><b style='mso-bidi-font-weight:normal'><span lang=EN-US>unit<o:p></o:p></span></b></p>
-  </td>
-  <td width=189 valign=top style='width:5.0cm;border:solid windowtext 1.0pt;
-  border-left:none;mso-border-left-alt:solid windowtext .5pt;mso-border-alt:
-  solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><b style='mso-bidi-font-weight:normal'><span lang=EN-US>reference<o:p></o:p></span></b></p>
-  </td>
- </tr>
- <tr style='mso-yfti-irow:1'>
-  <td width=92 rowspan=5 valign=top style='width:69.2pt;border:solid windowtext 1.0pt;
-  border-top:none;mso-border-top-alt:solid windowtext .5pt;mso-border-alt:solid windowtext .5pt;
-  padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>sensor</span></p>
-  </td>
-  <td width=85 valign=top style='width:63.8pt;border-top:none;border-left:none;
-  border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>KdegOxyR</span></p>
-  </td>
-  <td width=136 valign=top style='width:102.1pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>OxyR degrading rate</span></p>
-  </td>
-  <td width=102 valign=top style='width:76.6pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>10<sup>7</sup></span></p>
-  </td>
-  <td width=57 valign=top style='width:42.55pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>M<sup>-1</sup> x min<sup>-1</sup></span></p>
-  </td>
-  <td width=189 rowspan=3 valign=top style='width:5.0cm;border-top:none;
-  border-left:none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>Regulation of the OxyR transcription
-  factor by hydrogen peroxide and the cellular thiol—disulfide status</span></p>
-  <p class=MsoNormal><span lang=EN-US><o:p>&nbsp;</o:p></span></p>
-  </td>
- </tr>
- <tr style='mso-yfti-irow:2'>
-  <td width=85 valign=top style='width:63.8pt;border-top:none;border-left:none;
-  border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>KdROSOxyR</span></p>
-  </td>
-  <td width=136 valign=top style='width:102.1pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>Dissociation constant of ROS-OxyR complex</span></p>
-  </td>
-  <td width=102 valign=top style='width:76.6pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>10<sup>-7.33</sup> </span></p>
-  <p class=MsoNormal><span lang=EN-US><o:p>&nbsp;</o:p></span></p>
-  </td>
-  <td width=57 valign=top style='width:42.55pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>M</span></p>
-  </td>
- </tr>
- <tr style='mso-yfti-irow:3'>
-  <td width=85 valign=top style='width:63.8pt;border-top:none;border-left:none;
-  border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>KoxyR</span></p>
-  </td>
-  <td width=136 valign=top style='width:102.1pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>OxyR producing rate constant</span></p>
-  </td>
-  <td width=102 valign=top style='width:76.6pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>5.012 x 10<sup>14</sup></span></p>
-  </td>
-  <td width=57 valign=top style='width:42.55pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>-</span></p>
-  </td>
- </tr>
- <tr style='mso-yfti-irow:4'>
-  <td width=85 valign=top style='width:63.8pt;border-top:none;border-left:none;
-  border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>nROSOxyR</span></p>
-  </td>
-  <td width=136 valign=top style='width:102.1pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>Hill coefficient of ROS-OxyR complex</span></p>
-  </td>
-  <td width=102 valign=top style='width:76.6pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>Ranging from0.75~</span></p>
-  <p class=MsoNormal><span lang=EN-US>3.5,depends on what kind of ROS it binds</span></p>
-  </td>
-  <td width=57 valign=top style='width:42.55pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>-</span></p>
-  </td>
-  <td width=189 valign=top style='width:5.0cm;border-top:none;border-left:none;
-  border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>OxyR: A Molecular Code for Redox-Related
-  Signaling</span></p>
-  </td>
- </tr>
- <tr style='mso-yfti-irow:5'>
-  <td width=85 valign=top style='width:63.8pt;border-top:none;border-left:none;
-  border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>N</span></p>
-  </td>
-  <td width=136 valign=top style='width:102.1pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>Copy number</span></p>
-  </td>
-  <td width=102 valign=top style='width:76.6pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>887(cells containing25</span><span
-  style='font-family:"新細明體","serif"'>％</span> <span lang=EN-US>plasmid bearing
-  cells)</span></p>
-  </td>
-  <td width=57 valign=top style='width:42.55pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>Single</span></p>
-  <p class=MsoNormal><span lang=EN-US>piece</span></p>
-  </td>
-  <td width=189 valign=top style='width:5.0cm;border-top:none;border-left:none;
-  border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoListParagraph style='margin-left:18.0pt;mso-para-margin-left:
-gd;text-indent:-18.0pt;mso-list:l3 level1 lfo5'><![if !supportLists]><span
-  lang=EN-US style='mso-fareast-font-family:Calibri;mso-fareast-theme-font:
-  minor-latin;mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin'><span
-  style='mso-list:Ignore'>1.<span style='font:7.0pt "Times New Roman"'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
-  </span></span></span><![endif]><span lang=EN-US>Escherichia coli Plasmid Copy
-  Number Assay</span></p>
-  <p class=MsoListParagraph style='margin-left:18.0pt;mso-para-margin-left:
-gd;text-indent:-18.0pt;mso-list:l3 level1 lfo5'><![if !supportLists]><span
-  lang=EN-US style='mso-fareast-font-family:Calibri;mso-fareast-theme-font:
-  minor-latin;mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin'><span
-  style='mso-list:Ignore'>2.<span style='font:7.0pt "Times New Roman"'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
-  </span></span></span><![endif]><span lang=EN-US>Improved determination of plasmid
-  copy number using quantitative real-time PCR for monitoring fermentation
-  processes</span></p>
-  </td>
- </tr>
- <tr style='mso-yfti-irow:6'>
-  <td width=92 rowspan=3 valign=top style='width:69.2pt;border:solid windowtext 1.0pt;
-  border-top:none;mso-border-top-alt:solid windowtext .5pt;mso-border-alt:solid windowtext .5pt;
-  padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>Ethanol</span></p>
-  </td>
-  <td width=85 valign=top style='width:63.8pt;border-top:none;border-left:none;
-  border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>pyruvate</span></p>
-  </td>
-  <td width=136 valign=top style='width:102.1pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>Initial concentration of pyruvate in
-  MG1655</span></p>
-  </td>
-  <td width=102 valign=top style='width:76.6pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>1.18 x 2 </span></p>
-  </td>
-  <td width=57 valign=top style='width:42.55pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>g/L</span></p>
-  </td>
-  <td width=189 valign=top style='width:5.0cm;border-top:none;border-left:none;
-  border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>Expression of Pyruvate Carboxylase
-  Enhances Succinate Production in Escherichia coli without Affecting Glucose
-  Uptake</span></p>
-  </td>
- </tr>
- <tr style='mso-yfti-irow:7'>
-  <td width=85 valign=top style='width:63.8pt;border-top:none;border-left:none;
-  border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US style='font-size:10.0pt;mso-font-kerning:
-pt'>nPDC<o:p></o:p></span></p>
-  </td>
-  <td width=136 valign=top style='width:102.1pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US style='font-size:10.0pt;mso-font-kerning:
-pt'>Hill coefficient of PDC<o:p></o:p></span></p>
-  </td>
-  <td width=102 valign=top style='width:76.6pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>2.1</span></p>
-  </td>
-  <td width=57 valign=top style='width:42.55pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>-</span></p>
-  </td>
-  <td width=189 valign=top style='width:5.0cm;border-top:none;border-left:none;
-  border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>Purification, characterization and cDNA
-  sequencing of pyruvate decarboxylase Zygosaccharomyces biporus</span></p>
-  </td>
- </tr>
- <tr style='mso-yfti-irow:8'>
-  <td width=85 valign=top style='width:63.8pt;border-top:none;border-left:none;
-  border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US style='font-size:10.0pt;mso-font-kerning:
-pt'>nADH<o:p></o:p></span></p>
-  </td>
-  <td width=136 valign=top style='width:102.1pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US style='font-size:10.0pt;mso-font-kerning:
-pt'>Hill coefficient of ADH<o:p></o:p></span></p>
-  </td>
-  <td width=102 valign=top style='width:76.6pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>at high pH values, 30&#9702;C, n=1; at low
-  temperature, n=3</span></p>
-  </td>
-  <td width=57 valign=top style='width:42.55pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>-</span></p>
-  </td>
-  <td width=189 valign=top style='width:5.0cm;border-top:none;border-left:none;
-  border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>Evidence for co-operativity in coenzyme
-  binding to tetrameric Sulfolobus</span></p>
-  <p class=MsoNormal><span lang=EN-US>solfataricus alcohol dehydrogenase and
-  its structural basis: &#64258;uorescence,</span></p>
-  <p class=MsoNormal><span lang=EN-US>kinetic and structural studies of the
-  wild-type enzyme and non-co-operative</span></p>
-  <p class=MsoNormal><span lang=EN-US>N249Y mutant</span></p>
-  </td>
- </tr>
- <tr style='mso-yfti-irow:9'>
-  <td width=92 rowspan=6 valign=top style='width:69.2pt;border:solid windowtext 1.0pt;
-  border-top:none;mso-border-top-alt:solid windowtext .5pt;mso-border-alt:solid windowtext .5pt;
-  padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>SEIR(exponential)</span></p>
-  <p class=MsoNormal><span lang=EN-US><o:p>&nbsp;</o:p></span></p>
-  </td>
-  <td width=85 valign=top style='width:63.8pt;border-top:none;border-left:none;
-  border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>b</span></p>
-  </td>
-  <td width=136 valign=top style='width:102.1pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>Infection rate</span><span lang=EN-US
-  style='font-family:"新細明體","serif";mso-ascii-theme-font:minor-fareast;
-  mso-fareast-font-family:新細明體;mso-fareast-theme-font:minor-fareast;mso-hansi-theme-font:
-  minor-fareast'> </span><span lang=EN-US>constant of <i style='mso-bidi-font-style:
-  normal'>Nosema ceranae</i> to the suspected</span></p>
-  </td>
-  <td width=102 valign=top style='width:76.6pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>24/75 </span></p>
-  </td>
-  <td width=57 valign=top style='width:42.55pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>Period(days)<sup>-1</sup></span></p>
-  </td>
-  <td width=189 valign=top style='width:5.0cm;border-top:none;border-left:none;
-  border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US><o:p>&nbsp;</o:p></span></p>
-  </td>
- </tr>
- <tr style='mso-yfti-irow:10'>
-  <td width=85 valign=top style='width:63.8pt;border-top:none;border-left:none;
-  border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>r1</span></p>
-  </td>
-  <td width=136 valign=top style='width:102.1pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>Infection rate</span><span lang=EN-US
-  style='font-family:"新細明體","serif";mso-ascii-theme-font:minor-fareast;
-  mso-fareast-font-family:新細明體;mso-fareast-theme-font:minor-fareast;mso-hansi-theme-font:
-  minor-fareast'> </span><span lang=EN-US>constant of K12 to the suspected</span></p>
-  </td>
-  <td width=102 valign=top style='width:76.6pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>3/20 </span></p>
-  </td>
-  <td width=57 valign=top style='width:42.55pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>Period(days)<sup>-1</sup></span></p>
-  </td>
-  <td width=189 valign=top style='width:5.0cm;border-top:none;border-left:none;
-  border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoListParagraph style='margin-left:18.0pt;mso-para-margin-left:
-gd;text-indent:-18.0pt;mso-list:l5 level1 lfo6'><![if !supportLists]><span
-  lang=EN-US style='mso-fareast-font-family:Calibri;mso-fareast-theme-font:
-  minor-latin;mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin'><span
-  style='mso-list:Ignore'>1.<span style='font:7.0pt "Times New Roman"'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
-  </span></span></span><![endif]><span lang=EN-US>Environment protection
-  administration executive yuan of R.O.C</span></p>
-  <p class=MsoNormal><span lang=EN-US>Medical bacteriology of J.A.T</span></p>
-  </td>
- </tr>
- <tr style='mso-yfti-irow:11'>
-  <td width=85 valign=top style='width:63.8pt;border-top:none;border-left:none;
-  border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>r2</span></p>
-  </td>
-  <td width=136 valign=top style='width:102.1pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>Infection rate</span><span lang=EN-US
-  style='font-family:"新細明體","serif";mso-ascii-theme-font:minor-fareast;
-  mso-fareast-font-family:新細明體;mso-fareast-theme-font:minor-fareast;mso-hansi-theme-font:
-  minor-fareast'> </span><span lang=EN-US>constant of K12 to the latent</span></p>
-  </td>
-  <td width=102 valign=top style='width:76.6pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>3/20 </span></p>
-  </td>
-  <td width=57 valign=top style='width:42.55pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>Period(days)<sup>-1</sup></span></p>
-  </td>
-  <td width=189 rowspan=2 valign=top style='width:5.0cm;border-top:none;
-  border-left:none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoListParagraph style='margin-left:18.0pt;mso-para-margin-left:
-gd;text-indent:-18.0pt;mso-list:l5 level1 lfo6'><![if !supportLists]><span
-  lang=EN-US style='mso-fareast-font-family:Calibri;mso-fareast-theme-font:
-  minor-latin;mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin'><span
-  style='mso-list:Ignore'>2.<span style='font:7.0pt "Times New Roman"'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
-  </span></span></span><![endif]><span lang=EN-US>Environment protection
-  administration executive yuan of R.O.C</span></p>
-  <p class=MsoListParagraph style='margin-left:18.0pt;mso-para-margin-left:
-gd;text-indent:-18.0pt;mso-list:l5 level1 lfo6'><![if !supportLists]><span
-  lang=EN-US style='mso-fareast-font-family:Calibri;mso-fareast-theme-font:
-  minor-latin;mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin'><span
-  style='mso-list:Ignore'>3.<span style='font:7.0pt "Times New Roman"'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
-  </span></span></span><![endif]><span lang=EN-US>Medical bacteriology of J.A.T</span></p>
-  <p class=MsoListParagraph style='margin-left:18.0pt;mso-para-margin-left:
-gd;text-indent:-18.0pt;mso-list:l5 level1 lfo6'><![if !supportLists]><span
-  lang=EN-US style='mso-fareast-font-family:Calibri;mso-fareast-theme-font:
-  minor-latin;mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin'><span
-  style='mso-list:Ignore'>4.<span style='font:7.0pt "Times New Roman"'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
-  </span></span></span><![endif]><span lang=EN-US><o:p>&nbsp;</o:p></span></p>
-  </td>
- </tr>
- <tr style='mso-yfti-irow:12'>
-  <td width=85 valign=top style='width:63.8pt;border-top:none;border-left:none;
-  border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>e</span></p>
-  </td>
-  <td width=136 valign=top style='width:102.1pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>rate of the latent turns infectious</span></p>
-  </td>
-  <td width=102 valign=top style='width:76.6pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>1/4</span></p>
-  </td>
-  <td width=57 valign=top style='width:42.55pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>Period(days)<sup>-1</sup></span></p>
-  </td>
- </tr>
- <tr style='mso-yfti-irow:13'>
-  <td width=85 valign=top style='width:63.8pt;border-top:none;border-left:none;
-  border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>u</span></p>
-  </td>
-  <td width=136 valign=top style='width:102.1pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>Death rate of the infected</span></p>
-  </td>
-  <td width=102 valign=top style='width:76.6pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>1/8</span></p>
-  </td>
-  <td width=57 valign=top style='width:42.55pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>Period(days)<sup>-1</sup></span></p>
-  </td>
-  <td width=189 valign=top style='width:5.0cm;border-top:none;border-left:none;
-  border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US><o:p>&nbsp;</o:p></span></p>
-  </td>
- </tr>
- <tr style='mso-yfti-irow:14'>
-  <td width=85 valign=top style='width:63.8pt;border-top:none;border-left:none;
-  border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>k</span></p>
-  </td>
-  <td width=136 valign=top style='width:102.1pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>Rate of intaking capsule</span></p>
-  </td>
-  <td width=102 valign=top style='width:76.6pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>24/11</span></p>
-  <p class=MsoNormal><span lang=EN-US><o:p>&nbsp;</o:p></span></p>
-  </td>
-  <td width=57 valign=top style='width:42.55pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>Period(days)<sup>-1</sup></span></p>
-  </td>
-  <td width=189 valign=top style='width:5.0cm;border-top:none;border-left:none;
-  border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US><o:p>&nbsp;</o:p></span></p>
-  </td>
- </tr>
- <tr style='mso-yfti-irow:15'>
-  <td width=92 rowspan=5 valign=top style='width:69.2pt;border:solid windowtext 1.0pt;
-  border-top:none;mso-border-top-alt:solid windowtext .5pt;mso-border-alt:solid windowtext .5pt;
-  padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>SEIR(exponential&amp;linear)</span></p>
-  <p class=MsoNormal><span lang=EN-US><o:p>&nbsp;</o:p></span></p>
-  </td>
-  <td width=85 valign=top style='width:63.8pt;border-top:none;border-left:none;
-  border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>S</span></p>
-  </td>
-  <td width=136 valign=top style='width:102.1pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>x(1)</span></p>
-  </td>
-  <td width=102 valign=top style='width:76.6pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>Amount of total population</span></p>
-  </td>
-  <td width=57 valign=top style='width:42.55pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US><o:p>&nbsp;</o:p></span></p>
-  </td>
-  <td width=189 valign=top style='width:5.0cm;border-top:none;border-left:none;
-  border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US><o:p>&nbsp;</o:p></span></p>
-  </td>
- </tr>
- <tr style='mso-yfti-irow:16'>
-  <td width=85 valign=top style='width:63.8pt;border-top:none;border-left:none;
-  border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>E</span></p>
-  </td>
-  <td width=136 valign=top style='width:102.1pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>x(2)</span></p>
-  </td>
-  <td width=102 valign=top style='width:76.6pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>Amount of suspected individuals</span></p>
-  </td>
-  <td width=57 valign=top style='width:42.55pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><b style='mso-bidi-font-weight:normal'><span lang=EN-US><o:p>&nbsp;</o:p></span></b></p>
-  </td>
-  <td width=189 valign=top style='width:5.0cm;border-top:none;border-left:none;
-  border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><b style='mso-bidi-font-weight:normal'><span lang=EN-US><o:p>&nbsp;</o:p></span></b></p>
-  </td>
- </tr>
- <tr style='mso-yfti-irow:17'>
-  <td width=85 valign=top style='width:63.8pt;border-top:none;border-left:none;
-  border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>I</span></p>
-  </td>
-  <td width=136 valign=top style='width:102.1pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>x(3)</span></p>
-  </td>
-  <td width=102 valign=top style='width:76.6pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>Amount of individuals in the latent
-  period</span></p>
-  </td>
-  <td width=57 valign=top style='width:42.55pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><b style='mso-bidi-font-weight:normal'><span lang=EN-US><o:p>&nbsp;</o:p></span></b></p>
-  </td>
-  <td width=189 valign=top style='width:5.0cm;border-top:none;border-left:none;
-  border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><b style='mso-bidi-font-weight:normal'><span lang=EN-US><o:p>&nbsp;</o:p></span></b></p>
-  </td>
- </tr>
- <tr style='mso-yfti-irow:18'>
-  <td width=85 valign=top style='width:63.8pt;border-top:none;border-left:none;
-  border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>R</span></p>
-  </td>
-  <td width=136 valign=top style='width:102.1pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>x(4)</span></p>
-  </td>
-  <td width=102 valign=top style='width:76.6pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US>Amount of infected individuals</span></p>
-  </td>
-  <td width=57 valign=top style='width:42.55pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><b style='mso-bidi-font-weight:normal'><span lang=EN-US><o:p>&nbsp;</o:p></span></b></p>
-  </td>
-  <td width=189 valign=top style='width:5.0cm;border-top:none;border-left:none;
-  border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><b style='mso-bidi-font-weight:normal'><span lang=EN-US><o:p>&nbsp;</o:p></span></b></p>
-  </td>
- </tr>
- <tr style='mso-yfti-irow:19;mso-yfti-lastrow:yes'>
-  <td width=85 valign=top style='width:63.8pt;border-top:none;border-left:none;
-  border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US><o:p>&nbsp;</o:p></span></p>
-  </td>
-  <td width=136 valign=top style='width:102.1pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US><o:p>&nbsp;</o:p></span></p>
-  </td>
-  <td width=102 valign=top style='width:76.6pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><span lang=EN-US><o:p>&nbsp;</o:p></span></p>
-  </td>
-  <td width=57 valign=top style='width:42.55pt;border-top:none;border-left:
-  none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><b style='mso-bidi-font-weight:normal'><span lang=EN-US><o:p>&nbsp;</o:p></span></b></p>
-  </td>
-  <td width=189 valign=top style='width:5.0cm;border-top:none;border-left:none;
-  border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;
-  mso-border-top-alt:solid windowtext .5pt;mso-border-left-alt:solid windowtext .5pt;
-  mso-border-alt:solid windowtext .5pt;padding:0cm 5.4pt 0cm 5.4pt'>
-  <p class=MsoNormal><b style='mso-bidi-font-weight:normal'><span lang=EN-US><o:p>&nbsp;</o:p></span></b></p>
-  </td>
- </tr>
-</table>
-<p class=MsoNormal><span lang=EN-US><o:p>&nbsp;</o:p></span></p>
-</div>
-</body>
-</html>
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