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Team:Freiburg
From 2013.igem.org
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<div id="text_gross" align="left"> <a href="https://2013.igem.org/Team:Freiburg/HumanPractice"> Human <br><br> Practice </a> </div> | <div id="text_gross" align="left"> <a href="https://2013.igem.org/Team:Freiburg/HumanPractice"> Human <br><br> Practice </a> </div> | ||
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<img id="klammer_klein_rechts" src="https://static.igem.org/mediawiki/2013/8/82/Freiburg_2013_main2_Rahmen_gross_rechts.png"> | <img id="klammer_klein_rechts" src="https://static.igem.org/mediawiki/2013/8/82/Freiburg_2013_main2_Rahmen_gross_rechts.png"> | ||
Revision as of 14:46, 1 October 2013
Our Team developed a universal toolkit, termed uniCAS, that enables customizable gene
regulation in mammalian cells. Therefore, we engineered the recently discovered and highly promising
CRISPR/Cas9 system.
The regulation is based on the RNA-guided Cas9 protein, which allows targeting of specific DNA sequences. Our toolkit comprises not only a standardized Cas9 protein, but also different effector domains for efficient gene activation or repression. 
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