Team:Freiburg/Highlights
From 2013.igem.org
Line 222: | Line 222: | ||
<ul style="font-size:18px"> | <ul style="font-size:18px"> | ||
- | <li>...construct a | + | <li>...construct a catalytically inactive version of <b>Cas9</b> and thus generate a new <b>DNA binding protein</b>.</li> |
<li>...combine this modified dCas9 with <b>different transcriptional effectors</b>.</li> | <li>...combine this modified dCas9 with <b>different transcriptional effectors</b>.</li> | ||
- | <li>...express this system in various <b>mammalian | + | <li>...<b>express</b> this system in various <b>mammalian</b> cell lines.</li> |
- | <li>... | + | <li>...<b>control mammalian gene expression</b> via our modified CRISPR/Cas system.</li> |
<li>...regulate gene expression on <b>light stimulus</b>.</li> | <li>...regulate gene expression on <b>light stimulus</b>.</li> | ||
- | <li>...make our <b> | + | <li>...make our dCas9 <b>accessible to the whole iGEM community</b> by mutating illegal iGEM restriction sites</b>.</li> |
<br> | <br> | ||
In summary we build up a <b>universal applicable toolkit for gene regulation</b>. | In summary we build up a <b>universal applicable toolkit for gene regulation</b>. |
Revision as of 00:12, 3 October 2013
HIGHLIGHTS
In the last months we were able to...
In summary we build up a universal applicable toolkit for gene regulation. |
||
|
||
|
||
|
||
|
||
|
||
|