Team:INSA Toulouse/contenu/project/biological construction

From 2013.igem.org

(Difference between revisions)
Line 78: Line 78:
   <h1 class="title1">Biological Modules</h1>
   <h1 class="title1">Biological Modules</h1>
-
   <p class="texte">The first question we had to face for the <i>E.calculus</i> project was: “how can we transpose an electronic device into a reasonable biological system?”
+
   <p class="texte">The first question we had to face for the <i>E.calculus</i> project was the transposition of an electronic device into a reasonable biological system.
-
<br>The diagramm of an electronic full adder can be divided into two independant parts : Input and Output signals (A, B, C<sub>in</sub>, S, C<sub>out</sub>) and logic gates (XOR, AND, OR). THe rational for doing this classification was: logic gates can be universal but input and output signals must be adaptable for diverse applications and microorganisms.</p>
+
<br>The diagram of an electronic full adder (see below) can be divided into three independant parts : Input and Output signals (A, B, C<sub>in</sub>, S, C<sub>out</sub>) and logic gates (XOR, AND, OR). The rationale for doing this classification was: logic gates can be universal but input and output signals must be adaptable for diverse applications and microorganisms.</p>
    
    
   <img src="https://static.igem.org/mediawiki/2013/2/2c/Full-adder.png" class="imgcontent" />
   <img src="https://static.igem.org/mediawiki/2013/2/2c/Full-adder.png" class="imgcontent" />
Line 92: Line 92:
   <h2 class="texte"> <span class="title2"><a href="https://2013.igem.org/Team:INSA_Toulouse/contenu/project/biological_construction/carry">Carry</span></h2>
   <h2 class="texte"> <span class="title2"><a href="https://2013.igem.org/Team:INSA_Toulouse/contenu/project/biological_construction/carry">Carry</span></h2>
-
   <p class="texte">The carry,(C<sub>in</sub> and C<sub>out</sub>) out a molecule that can transmit a message from one colony to an other was essential. </a></p>
+
   <p class="texte">The carry (C<sub>in</sub> and C<sub>out</sub>), belongs to both the input and output modules. We thought of a molecule that could transmit a message from one colony to the other. </a></p>
Line 100: Line 100:
   <h2 class="texte"> <span class="title2"><a href="https://2013.igem.org/Team:INSA_Toulouse/contenu/project/biological_construction/full_adder">Full Adder</span></h2>
   <h2 class="texte"> <span class="title2"><a href="https://2013.igem.org/Team:INSA_Toulouse/contenu/project/biological_construction/full_adder">Full Adder</span></h2>
-
   <p class="texte">The initegration of the signals (input, ouput, carry) with the logic gates leads to the full adder. The description of the full biological adder can be found here.</a></p>
+
   <p class="texte">The full adder is the integration of the signals (input, ouput, carry) with the logic gates. Its biological description can be found here.</a></p>

Revision as of 09:25, 3 October 2013

logo


Biological Modules

The first question we had to face for the E.calculus project was the transposition of an electronic device into a reasonable biological system.
The diagram of an electronic full adder (see below) can be divided into three independant parts : Input and Output signals (A, B, Cin, S, Cout) and logic gates (XOR, AND, OR). The rationale for doing this classification was: logic gates can be universal but input and output signals must be adaptable for diverse applications and microorganisms.

Input

For the input, we needed a signal that could easily represents "ON" and "OFF" states. Light came as a natural solution because it is easily switchable to "ON" and "OFF" states and color can be varied to represent several inputs (A and B).

Output

The output needed to be a signal that can be easily seen without any complicated device or apparatus, something visual like the color of the organism bearing the full adder.

Carry

The carry (Cin and Cout), belongs to both the input and output modules. We thought of a molecule that could transmit a message from one colony to the other.

Logic Gates

An electronic full adder is composed of 5 logic gates. Transcriptionally regulated logic gates exist and have already been described. However, a major breakthrough in Synthetic Biology appeared during 2013 with two publications related to recombination based logic gates. They inspired us and are the basis of our work.

Full Adder

The full adder is the integration of the signals (input, ouput, carry) with the logic gates. Its biological description can be found here.