Team:Evry/Achievements

From 2013.igem.org

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<li>(Improve the function of an existing BioBrick Part or Device) => LacO RFP
<li>(Improve the function of an existing BioBrick Part or Device) => LacO RFP
<li>Help any registered iGEM team
<li>Help any registered iGEM team
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<li class="tick">Your project may have implications for the environment, security, safety and ethics and/or ownership and sharing.
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<li class="tick">As our project involves treating a human genetic disorder using genetically-engineered bacteria, it has numerous implications for human health, safety and security, and ethics. We explored these issues as follows:
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<li> We discussed the medical implications of this treatment in a <a href="https://2013.igem.org/Team:Evry/HumanPractice/Expert_consultation" target='_blank'>series of interviews and discussion</a> with renowned experts on iron overload diseases.</li>
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<li>We carefully considered the <b><a href="https://2013.igem.org/Team:Evry/Safety" target='_blank'>safety issues</a></b> and potential consequences of our bacteria, which are illustrated in this consequence tree.
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<ul>
<ul>
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<li class="tick">We make a <a href="https://2013.igem.org/Team:Evry/HumanPractice/Expert_consultation" target='_blank'>series of <b>interviews and discussion</b></a> with <b>experts on iron overload diseases</b>.
 
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<li class="tick">We make <b>reflexion</b> about the <b><a href="https://2013.igem.org/Team:Evry/Safety" target='_blank'>safety</a></b> of potential consequences of our bacteria, including a <b>consequence tree</b>.
 
  <li class="tick">We had discussion with hemochromatosis patient and held a <b><a href="https://2013.igem.org/Team:Evry/Seminar" target='_blank'>seminar</a></b> on <b>iron overload</b> and on <b>our project</b> on 18 September 2013.<br/>
  <li class="tick">We had discussion with hemochromatosis patient and held a <b><a href="https://2013.igem.org/Team:Evry/Seminar" target='_blank'>seminar</a></b> on <b>iron overload</b> and on <b>our project</b> on 18 September 2013.<br/>
<b>Scientists</b> working on iron overload, <b>patients</b>, and <b>students</b> attended to it !
<b>Scientists</b> working on iron overload, <b>patients</b>, and <b>students</b> attended to it !

Revision as of 08:21, 4 October 2013

Iron coli project

iGEM Evry 2013 achievements


Here we detail how we fulfilled each of the iGEM medal requirements.

Gold MedalGold Medal (requires any one of the following goals)

  • (Improve the function of an existing BioBrick Part or Device) => LacO RFP
  • Help any registered iGEM team
  • As our project involves treating a human genetic disorder using genetically-engineered bacteria, it has numerous implications for human health, safety and security, and ethics. We explored these issues as follows:
    1. We discussed the medical implications of this treatment in a series of interviews and discussion with renowned experts on iron overload diseases.
    2. We carefully considered the safety issues and potential consequences of our bacteria, which are illustrated in this consequence tree.

Silver MedalSilver Medal (requires each of the four following goals)


Bronze MedalBronze Medal (requires each of the five following goals)



And more precisely ?!

Biology

  • We design and create 4 Iron sensing systems, that could also works with an invertor !
  • We design an Iron chelating system and isolate genes of the enterobactins biosynthesis pathway !
  • We use TECAN and microfluidic to analyse our systems and show that they work !
  • We created a pill adapted to our project and that fulfilled basic requirements of the European Pharmacopeia !

Model

Human Practices

  • We had discussion with hemochromatosis patient and held a seminar on iron overload and on our project on 18 September 2013.
    Scientists working on iron overload, patients, and students attended to it !
  • We make a survey about hemochromatosis and about our potential treatment.
    We received and analyzed more than 250 answers from patients !
  • We submitted an extensive report of our conclusions about synthetic biology , which is the fruit of our long reflection we conducted over the summer.