Team:ZJU-China/Project/Standardization/Background

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Revision as of 12:45, 27 October 2013

Overview

Bacterial Ghost

Background Design Results

The Ghost Kit

Ghost Sensor Ghost Sponge Ghost Shell The Ghost Kit

Characterization

Background Results

Safety

Overview Artificial Shell E.coli Suicide Safety Form

Parts

Overview BBa_K1054000 BBa_K1054001 BBa_K1054002 BBa_K1054003 BBa_K1054007 BBa_K1054008 BBa_K1054009 BBa_K1054010 BBa_K1054011 BBa_K1054012 BBa_K1054013 BBa_K1054014 BBa_K1054015 BBa_K1054016 BBa_K1054017 BBa_K1054018 BBa_K1054019 BBa_K1054020 BBa_K1054021 BBa_K1054022 BBa_K1054023

Characterization: Background

Quantitative and qualitative descriptions of devices in the form of standardized datasheet and graph are commonly used in engineering disciplines. These datasheet and graphs enable the engineers to make quick decision whether the device and part will meet the requirement of a system in which they might be used.

Synthetic biology, as an area of biological research and technology that combines biology and engineering, is about to design and construct biological devices and systems for useful purpose and usually involves standardized parts and devices. Thus we believe description of riboswitches’ behavior will be of great significance for future iGEM teams and synthetic biologists.

A crucial characteristic is Static Performance, which is about to measure the transfer function, details the relation between device input(s) and output(s) and allows prediction of the behavior of composed devices.

The Dynamic Performance, which reports the response time, is often required since our riboswitch will have to work with other devices in an overall system.

The third characteristic is Input Specificity, which is intended to describe the behavior of our riboswitches when induced by some substances having similar structure with their own inducers and offer us a profound understanding of riboswitches.

In contrast with the Regional Jamboree, we added another criteria, Performance Reliability, for World Championship Jamboree. To establish a system that is able to run smoothly and continuously, the expected time to failure of a device or correct device performance over longer timescales, which is described with Performance Reliability, is urgently required.

Reference Canton B, Labno A, Endy D. Refinement and standardization of synthetic biological parts and devices[J]. Nature biotechnology, 2008, 26(7): 787-793.

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 == Characterization: Background ==
-Synthetic biology is about to design and construct biological devices and systems for useful purpose, which usually involves standardized parts and devices. And we believe behavior descriptions of riboswitches and aptamers will be quite helpful for the future iGEM teams and synthetics biologists considering their high specificity and affinity.
+Quantitative and qualitative descriptions of devices in the form of standardized datasheet and graph are commonly used in engineering disciplines. These datasheet and graphs enable the engineers to make quick decision whether the device and part will meet the requirement of a system in which they might be used.
-Our intended characteristics describing the behavior of the riboswitches consist of the followings:
+Synthetic biology, as an area of biological research and technology that combines biology and engineering, is about to design and construct biological devices and systems for useful purpose and usually involves standardized parts and devices. Thus we believe description of riboswitches’ behavior will be of great significance for future iGEM teams and synthetic biologists.
-'''Static Relationship''', which is about to measure the transfer function, details the relation between device input(s) and output(s) and allows prediction of the equilibrium behavior of composed devices.
+A crucial characteristic is '''Static Performance''', which is about to measure the transfer function, details the relation between device input(s) and output(s) and allows prediction of the behavior of composed devices.
-'''Dynamic Relationship''', we believe it is of great importance to report the response time of the device since it will be of great necessity when working with other devices in overall system.
-'''Input Compatibility''', which is intended to describe the behavior of our riboswitches when induced by some substances having similar structure with their own inducers.
+The '''Dynamic Performance''', which reports the response time, is often required since our riboswitch will have to work with other devices in an overall system.
+The third characteristic is '''Input Specificity''', which is intended to describe the behavior of our riboswitches when induced by some substances having similar structure with their own inducers and offer us a profound understanding of riboswitches.
+In contrast with the Regional Jamboree, we added another criteria, '''Performance Reliability''', for World Championship Jamboree. To establish a system that is able to run smoothly and continuously, the expected time to failure of a device or correct device performance over longer timescales, which is described with Performance Reliability, is urgently required.