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Team:TU-Eindhoven/Chasis
From 2013.igem.org
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{{:Team:TU-Eindhoven/Template:FloatEnd | caption=Graphic description of CEST protein production device.| id=graphVersionDeviceFigure }} | {{:Team:TU-Eindhoven/Template:FloatEnd | caption=Graphic description of CEST protein production device.| id=graphVersionDeviceFigure }} | ||
| - | The current construct | + | The current construct can be observed in the figure below. The His-Tag, thrombine cleavage site and the terminator sequence optimize transcription and ultimately expression. |
{{:Team:TU-Eindhoven/Template:Float | position=right | size=8 }} | {{:Team:TU-Eindhoven/Template:Float | position=right | size=8 }} | ||
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* Human cell disguise vector | * Human cell disguise vector | ||
| - | The kill switch vector is constituted by the prodrug Ganciclovir/Herpes Simplex Virus Thymidine Kinase Enzyme system. Including this vector | + | The kill switch vector is constituted by the prodrug Ganciclovir/Herpes Simplex Virus Thymidine Kinase Enzyme system. Including this vector in our device will allow the termination of the bacterial device at any point of the CEST MRI process. This system is explained on detail in the [[Team:TU-Eindhoven/KillingMechanism| kill switch section of the project tab.]] |
The human cell disguise refers to the alteration that should be induced in the external layer of the bacteria in order to become invisible to the immune system and avoid causing an immune system response. The detailed change that E. coli should endured in described on the [[ Team:TU-Eindhoven/Applications | application section of the project tab]]. | The human cell disguise refers to the alteration that should be induced in the external layer of the bacteria in order to become invisible to the immune system and avoid causing an immune system response. The detailed change that E. coli should endured in described on the [[ Team:TU-Eindhoven/Applications | application section of the project tab]]. | ||
Revision as of 10:19, 26 September 2013
Section under construction. Sorry for the inconvenience, please come back again some other time.
