Team:USTC CHINA
From 2013.igem.org
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We hope to develop a fresh-expression transdermal vaccination. | We hope to develop a fresh-expression transdermal vaccination. | ||
<br />We hope everyone in this world could equally enjoy the benefit of medical progress.<br /> | <br />We hope everyone in this world could equally enjoy the benefit of medical progress.<br /> | ||
- | <a href="https://2013.igem.org/Team:USTC_CHINA/Project/ProjectDetails/Background">more | + | <a href="https://2013.igem.org/Team:USTC_CHINA/Project/ProjectDetails/Background">more</a> |
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<img class="img-right" src="https://static.igem.org/mediawiki/2013/8/8e/2013ustc-china_99.png" width="16" height="13" /></div> | <img class="img-right" src="https://static.igem.org/mediawiki/2013/8/8e/2013ustc-china_99.png" width="16" height="13" /></div> | ||
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As the core of our in-situ system,<br /> TD1-antigen expresser is designed<br /> and will share a great percentage of<br /> the total bacteria in our "band-aid". | As the core of our in-situ system,<br /> TD1-antigen expresser is designed<br /> and will share a great percentage of<br /> the total bacteria in our "band-aid". | ||
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- | <a href="https://2013.igem.org/Team:USTC_CHINA/Project/ProjectDetails/Design">more | + | <a href="https://2013.igem.org/Team:USTC_CHINA/Project/ProjectDetails/Design">more</a> |
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<img class="img-right" src="https://static.igem.org/mediawiki/2013/8/8e/2013ustc-china_99.png" width="16" height="13" /> | <img class="img-right" src="https://static.igem.org/mediawiki/2013/8/8e/2013ustc-china_99.png" width="16" height="13" /> | ||
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As one kind of our adjuvant expresser,<br />TD1-LTB is used to enhance the antigenicity.<br /> For LTB has so many advantages, it's a wild using adjuvant for most of exsiting injected vaccine. | As one kind of our adjuvant expresser,<br />TD1-LTB is used to enhance the antigenicity.<br /> For LTB has so many advantages, it's a wild using adjuvant for most of exsiting injected vaccine. | ||
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- | <a href="https://2013.igem.org/Team:USTC_CHINA/Project/ProjectDetails/Design">more | + | <a href="https://2013.igem.org/Team:USTC_CHINA/Project/ProjectDetails/Design">more</a> |
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<img class="img-right" src="https://static.igem.org/mediawiki/2013/8/8e/2013ustc-china_99.png" width="16" height="13" /> | <img class="img-right" src="https://static.igem.org/mediawiki/2013/8/8e/2013ustc-china_99.png" width="16" height="13" /> | ||
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It's worth mentioning that to improve the effects of <br />traditional vaccine, as another kind of our TD1-adjuvant expresser, KNFα bear the weight of our hope to increase the sensitivity of our immune system. | It's worth mentioning that to improve the effects of <br />traditional vaccine, as another kind of our TD1-adjuvant expresser, KNFα bear the weight of our hope to increase the sensitivity of our immune system. | ||
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- | <a href="https://2013.igem.org/Team:USTC_CHINA/Project/ProjectDetails/Design">more | + | <a href="https://2013.igem.org/Team:USTC_CHINA/Project/ProjectDetails/Design">more</a> |
</div> | </div> | ||
<img class="img-right" src="https://static.igem.org/mediawiki/2013/8/8e/2013ustc-china_99.png" width="16" height="13" /> | <img class="img-right" src="https://static.igem.org/mediawiki/2013/8/8e/2013ustc-china_99.png" width="16" height="13" /> | ||
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Reporter, which notifies users whether the status of vaccine patch is all right and when they can stick the patches to arms . Further more killing switch is existed in them as a biosafety guard. | Reporter, which notifies users whether the status of vaccine patch is all right and when they can stick the patches to arms . Further more killing switch is existed in them as a biosafety guard. | ||
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- | <a href="https://2013.igem.org/Team:USTC_CHINA/Project/ProjectDetails/Design">more | + | <a href="https://2013.igem.org/Team:USTC_CHINA/Project/ProjectDetails/Design">more</a> |
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<img class="img-right" src="https://static.igem.org/mediawiki/2013/8/8e/2013ustc-china_99.png" width="16" height="13" /> | <img class="img-right" src="https://static.igem.org/mediawiki/2013/8/8e/2013ustc-china_99.png" width="16" height="13" /> | ||
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<span>Molecules part</span><br /> | <span>Molecules part</span><br /> | ||
We took E.coli and the PET vector as the positive control and realized our ideas in the B.subtilis expression system based on PHT43 shuttle vector.<br /> | We took E.coli and the PET vector as the positive control and realized our ideas in the B.subtilis expression system based on PHT43 shuttle vector.<br /> | ||
- | <a href="https://2013.igem.org/Team:USTC_CHINA/Project/Results">more | + | <a href="https://2013.igem.org/Team:USTC_CHINA/Project/Results">more</a> |
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<img class="img-right" src="https://static.igem.org/mediawiki/2013/8/8e/2013ustc-china_99.png" width="16" height="13" /> | <img class="img-right" src="https://static.igem.org/mediawiki/2013/8/8e/2013ustc-china_99.png" width="16" height="13" /> | ||
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<span>Protein part</span><br /> | <span>Protein part</span><br /> | ||
Before we achieve fresh expression, we need first use purified protein to obtain exact data to verify our assumption.<br /> | Before we achieve fresh expression, we need first use purified protein to obtain exact data to verify our assumption.<br /> | ||
- | <a href="https://2013.igem.org/Team:USTC_CHINA/Project/ProjectDetails/Results">more | + | <a href="https://2013.igem.org/Team:USTC_CHINA/Project/ProjectDetails/Results">more</a> |
</div> | </div> | ||
<img class="img-right" src="https://static.igem.org/mediawiki/2013/8/8e/2013ustc-china_99.png" width="16" height="13" /> | <img class="img-right" src="https://static.igem.org/mediawiki/2013/8/8e/2013ustc-china_99.png" width="16" height="13" /> | ||
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<span>Mice experiments</span><br /> | <span>Mice experiments</span><br /> | ||
The most obvious character of our 2013USTC iGEM team is that we have not only achieved a series of molecule experiments but also tried mice experiments, which could be divided into transdermal experiments in vitro and animate mice experiments<br /> | The most obvious character of our 2013USTC iGEM team is that we have not only achieved a series of molecule experiments but also tried mice experiments, which could be divided into transdermal experiments in vitro and animate mice experiments<br /> | ||
- | <a href="https://2013.igem.org/Team:USTC_CHINA/Project/Results/FurthurWork">more | + | <a href="https://2013.igem.org/Team:USTC_CHINA/Project/Results/FurthurWork">more</a> |
</div> | </div> | ||
<img class="img-right" src="https://static.igem.org/mediawiki/2013/8/8e/2013ustc-china_99.png" width="16" height="13" /> | <img class="img-right" src="https://static.igem.org/mediawiki/2013/8/8e/2013ustc-china_99.png" width="16" height="13" /> |
Revision as of 18:18, 27 September 2013