Reflection on the Open Source concept

As part of our reflection on our participation to the iGEM competition and on the future of synthetic biology, we decided to work on the Open Source concept and on its impact in our society. Our work was divided in three parts.

- Discussion about the open source concept during small meetings we organised

- Interview of Ellen Jorgensen (co-founder and president of Genspace) about her views regarding open source in biology

- Development of a new open source PCR thermal cycle project.

Reflections on the Open Source concept

We organized meetings in which two or three of us presented a specific aspect of Open Source: what is open source, what is the place of the open source synbio in our economy, what comparison we can make between computer science and synbiology, what are the risks of biohacking.... After each presentation we debated, and we hightlighted the important questions we wanted to broach. A report on the different meetings we had is available here: .

Interview of Ellen Jorgensen

To further enrich our reflection on Open Source, we decided to interview Ellen Jorgensen about her views on Open Source in Biology. Ellen Jorgensen is the co-founder and president of Genspace (http://genspace.org/), a nonprofit organization dedicated to promoting citizen science and access to biotechnology.

Our conclusion<u/>

Thanks to this interview, we learnt more about genspace and about the motivation of people who participate to this movment. People from a wild diversity of field can experiment, can learn more about synBio, and build innovative projects. Experiments are controlled and secured, it is an important difference in comparaison with some biohakers in their garage. We think that this reglementation shows a mature reflection about the open source in synthetic biology : everyone can make it, but security is the most important thing. After the interview we discussed about the question of DNA property : can we put personal DNA on the internet, can we modified every DNA or can we talk about DNA property?

We would like to thanks Ellen for answering to our questions. It was a great moment.

The Open Source thermal cycler project

Our team decided to participate to the development of open source biology by designing an Open Source thermocycler, the PSPCR. We have created a PCR thermal cycler, trying to keep its price as low as possible (about 30€,i.e. $40) and therefore using salvaged materials and common tools. The PSPCR is the good example of the positive consequences of the development of Open Source in synthetic biology : everyone can make it, improve it and share it. The goal of this project was to share with other iGEM teams the PSPCR and to use it like a basic tool that could be improved.

Some parts of this project were carried out at the Electrolab in Nanterre (near Paris)

OPEN SOURCE PCR

Photos of our meetings and of the human practice team:

Writing by Caroline and Damir