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Team:Freiburg
From 2013.igem.org
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| - | <li style="margin-left: -40px; padding-bottom:12px;"><a href="https://2013.igem.org/Team:Freiburg/Project/effector# | + | <li style="margin-left: -40px; padding-bottom:12px;"><a href="https://2013.igem.org/Team:Freiburg/Project/effector#KRAB"> |
<span> Repression </span> | <span> Repression </span> | ||
<img src="https://static.igem.org/mediawiki/2013/e/e7/Repression_freiburg_13.png" style="height:55px;"> | <img src="https://static.igem.org/mediawiki/2013/e/e7/Repression_freiburg_13.png" style="height:55px;"> | ||
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| - | <li style="margin-bottom:-30px;"><a href="https://2013.igem.org/Team:Freiburg/Project/effector# | + | <li style="margin-bottom:-30px;"><a href="https://2013.igem.org/Team:Freiburg/Project/effector#G9a"> |
| - | <span> | + | <span> Stable Repression </span> |
<img src="https://static.igem.org/mediawiki/2013/3/31/Freiburg_2013_main2_Epigenetic.png"> | <img src="https://static.igem.org/mediawiki/2013/3/31/Freiburg_2013_main2_Epigenetic.png"> | ||
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Revision as of 11:09, 3 October 2013
Our Team developed a universal toolkit, termed uniCAS, that enables customizable gene
regulation in mammalian cells. Therefore, we engineered the recently discovered and highly promising
CRISPR/Cas9 system.
The regulation is based on the RNA-guided Cas9 protein, which allows targeting of specific DNA sequences. Our toolkit comprises not only a standardized Cas9 protein, but also different effector domains for efficient gene activation or repression. 
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