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Team:Evry/Modelmeta3
From 2013.igem.org
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<h2>Observations</h2> | <h2>Observations</h2> | ||
<p> | <p> | ||
| + | Here is the pathway of the enterobactin:<br/> | ||
| + | <div align="center"><img src="https://static.igem.org/mediawiki/2013/3/3b/EntBS.png"/ width="100%"></div> | ||
</p> | </p> | ||
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<h2>Goals</h2> | <h2>Goals</h2> | ||
<p> | <p> | ||
| + | |||
</p> | </p> | ||
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Those chemical equations naturally lead to this system:<br/> | Those chemical equations naturally lead to this system:<br/> | ||
<img src="https://static.igem.org/mediawiki/2013/4/48/ChimieODE.png"/><br/> | <img src="https://static.igem.org/mediawiki/2013/4/48/ChimieODE.png"/><br/> | ||
| - | Where | + | Where : |
| + | <img src="https://static.igem.org/mediawiki/2013/2/28/V1v2v3v4.jpg"/><br/> | ||
| + | Those velocities come from the <a href="https://2013.igem.org/Team:Evry/ChemicalTools">Chemical reasoning</a> page. | ||
</p> | </p> | ||
Revision as of 22:10, 28 October 2013
Final Enterobactin production model
Introduction
This is the final step of the Enterobactin production model. We just have to combine all the previous models and add the delay of enzymes production as well as the enterobactin production time.This model includes the synthetic sensing system, the inverter system and the chemical reactions leading to the enterobactin.
Observations
Here is the pathway of the enterobactin:
Goals
Materials and methods
Enzymes production
The first equations are taken from the sensing model and the inverter model.
The [mRNA] and [Enz] equations are alike. The prodction rates are Kr for the mRNA and Kp for the enzymmes, and both variables have a negative degadation term:
Enterobactin production
Now that we have all the equations needed from the Iron to the Enzymes concentrations, we can include the chemical delay of the enterobactin production.
The input of the chemical sytem is the chorismic acid, and the output is the enterobactin.
Those chemical equations naturally lead to this system:
Where :
Those velocities come from the Chemical reasoning page.
The final system:
Results
Conclusion
Models and scripts
References:
