Flush model overview

Introduction

In the very beginning of the project, we focused on iron absorption by the duodenum. We first had to model the behaviour of the duodenum regarding iron absorption to determine if a flush treatment strategy was viable. Then we wanted to model the flush treatment by simulating a flush of iron-chelating bacteria.

Disease model

We first modeled the iron absorption of a hemochromatosic patient using ODEs.

Here is the link to the disease model.

Treatment model

We then used the disease model as a base to develop our flush treatment model. It aims to answer the following question:
"Is it possible to chelate a significant amount of iron with a flush strategy?"

Here is the link to the treatment model.

Team:Evry/flush model

From 2013.igem.org

Flush model overview

Introduction

Disease model

Treatment model