Project

One major goal of Synthetic Biology is the transposition of electronic devices such as logic gates into genetic modules capables of circuit decisions. Recently (Siuti and al. 2013, Bonnet and al. 2013), highly original logical gates utilizing Serine recombinases were described, avoiding reversibility of the genetic switch and thus creating strong and robust genetic logical gates (AND, XOR, OR).
The E. calculus project exemplifies these genetic modules by creating a n-bits full-adder using the AND and XOR gates. The proposed design could perform a n bits counting with a carry. Our project could validate some of the original properties of these new genetic switches: irreversibility and accurate genetic transmission to the offspring