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Team:Freiburg
From 2013.igem.org
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<div id="text_gross" align="left"> <a style="position:absolute; top:678px; left:905px; z-index:2" href="https://2013.igem.org/Team:Freiburg/News"> News </a></div> | <div id="text_gross" align="left"> <a style="position:absolute; top:678px; left:905px; z-index:2" href="https://2013.igem.org/Team:Freiburg/News"> News </a></div> | ||
| + | See our <br> achievements! | ||
<img src="https://static.igem.org/mediawiki/2013/5/56/Best-foundational-advance-2013-freiburg.png" height="130" style="position:absolute; top:686px; left:940px; z-index:1"> | <img src="https://static.igem.org/mediawiki/2013/5/56/Best-foundational-advance-2013-freiburg.png" height="130" style="position:absolute; top:686px; left:940px; z-index:1"> | ||
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Revision as of 13:30, 22 November 2013
Our Team developed a universal toolkit, termed uniCAS, that enables customizable gene
regulation in mammalian cells. Therefore, we engineered the recently understood and highly promising
CRISPR/Cas9 system.
The regulation is based on the RNA-guided dCas9 protein, which allows specific targeting of DNA sequences. Our toolkit comprises not only a standardized dCas9 protein, but also different effector domains for efficient gene activation or repression. 
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