Team:Freiburg/Highlights
From 2013.igem.org
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<ul style="font-size:18px"> | <ul style="font-size:18px"> | ||
- | <li>...construct a <b>catalytically inactive version of Cas9</b> and thus generate a new | + | <li>...construct a <b>catalytically inactive version of Cas9</b> and thus generate a new DNA binding protein.</li> |
<li>...combine this modified dCas9 with <b>different transcriptional effectors</b>.</li> | <li>...combine this modified dCas9 with <b>different transcriptional effectors</b>.</li> | ||
<li>...express this system in various <b>mammalian cell lines</b>.</li> | <li>...express this system in various <b>mammalian cell lines</b>.</li> | ||
- | <li>...control | + | <li>...control mammalian <b>gene expression</b> via our modified CRISPR/Cas system.</li> |
<li>...regulate gene expression on <b>light stimulus</b>.</li> | <li>...regulate gene expression on <b>light stimulus</b>.</li> | ||
<li>...make our <b>dCas9 accessible to the whole iGEM community</b> by mutating illegal iGEM restriction sites</b>.</li> | <li>...make our <b>dCas9 accessible to the whole iGEM community</b> by mutating illegal iGEM restriction sites</b>.</li> | ||
<br> | <br> | ||
- | In summary we build up a <b>universal toolkit for gene regulation</b>. | + | In summary we build up a <b>universal applicable toolkit for gene regulation</b>. |
</ul> | </ul> |
Revision as of 00:11, 3 October 2013
HIGHLIGHTS
In the last months we were able to...
In summary we build up a universal applicable toolkit for gene regulation. |
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