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Team:HZAU-China/Modeling
From 2013.igem.org
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<p style="font-size:16px;font-family:arial, sans-serif;"><b>Abstract</b>:In order to know how many flea that carry our engineered strain could make the stray dogs in an area immune to the rabies virus, we developed computational models to simulate the process and to demonstrate our ideas. Our model consist of three parts: “immune response”, “gray logistic”, and “cellular automaton”. The “immune response” model is to analyze the kinetic relationship between the antigen and antibody during the immunologic processes. The “gray logistic” model is to simulate the growth curves of the Bacillus subtilis in the blood of dogs. The “cellular automaton” model is used to simulate the spread of our engineering bacteria in dogs.</p> | <p style="font-size:16px;font-family:arial, sans-serif;"><b>Abstract</b>:In order to know how many flea that carry our engineered strain could make the stray dogs in an area immune to the rabies virus, we developed computational models to simulate the process and to demonstrate our ideas. Our model consist of three parts: “immune response”, “gray logistic”, and “cellular automaton”. The “immune response” model is to analyze the kinetic relationship between the antigen and antibody during the immunologic processes. The “gray logistic” model is to simulate the growth curves of the Bacillus subtilis in the blood of dogs. The “cellular automaton” model is used to simulate the spread of our engineering bacteria in dogs.</p> | ||
| - | <p style="text-align:center;"><a><img width="500" src="https://static.igem.org/mediawiki/2013/1/1d/Gray.png" ></a></br></p> | + | <p style="text-align:center;"><a href="https://2013.igem.org/Team:HZAU-China/Modeling/Gray logistic"><img width="500" src="https://static.igem.org/mediawiki/2013/1/1d/Gray.png" ></a></br></p> |
<p style="font-size:13px;font-family:arial, sans-serif;text-align:center;">Predicted value and actual value changes over time</p> | <p style="font-size:13px;font-family:arial, sans-serif;text-align:center;">Predicted value and actual value changes over time</p> | ||
<div id="pic00"> | <div id="pic00"> | ||
<div id="pic01"> | <div id="pic01"> | ||
| - | <p style="text-align:center;padding-bottom:5px;"><a><img width="360" src="https://static.igem.org/mediawiki/2013/3/3c/The-antibody-consentration.png" ></a></br></p> | + | <p style="text-align:center;padding-bottom:5px;"><a href="https://2013.igem.org/Team:HZAU-China/Modeling/Immune responce" ><img width="360" src="https://static.igem.org/mediawiki/2013/3/3c/The-antibody-consentration.png" ></a></br></p> |
<p style="font-size:13px;font-family:arial, sans-serif;text-align:center;">The concentration of antibody and antigen during immune response</p> | <p style="font-size:13px;font-family:arial, sans-serif;text-align:center;">The concentration of antibody and antigen during immune response</p> | ||
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<div id="pic02"> | <div id="pic02"> | ||
| - | <p style="text-align:center;"><a><img width="250" src="https://static.igem.org/mediawiki/2013/b/b8/Cell.png" ></a></br></p> | + | <p style="text-align:center;"><a href="https://2013.igem.org/Team:HZAU-China/Modeling/Cellular automata"><img width="250" src="https://static.igem.org/mediawiki/2013/b/b8/Cell.png" ></a></br></p> |
<p style="font-size:13px;font-family:arial, sans-serif;text-align:center;"> The percentage of immune dogs</p> | <p style="font-size:13px;font-family:arial, sans-serif;text-align:center;"> The percentage of immune dogs</p> | ||
</div> | </div> | ||
Revision as of 13:52, 26 September 2013
Abstract:In order to know how many flea that carry our engineered strain could make the stray dogs in an area immune to the rabies virus, we developed computational models to simulate the process and to demonstrate our ideas. Our model consist of three parts: “immune response”, “gray logistic”, and “cellular automaton”. The “immune response” model is to analyze the kinetic relationship between the antigen and antibody during the immunologic processes. The “gray logistic” model is to simulate the growth curves of the Bacillus subtilis in the blood of dogs. The “cellular automaton” model is used to simulate the spread of our engineering bacteria in dogs.
Predicted value and actual value changes over time
The concentration of antibody and antigen during immune response
The percentage of immune dogs
