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Team:TU-Delft/BandAid
From 2013.igem.org
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sensing (QS), a cell-to-cell signalling mechanism, to enhance its ability to cause disease</html>[[Team:TUDelft/ReferencesBandAid|[1]]]. | sensing (QS), a cell-to-cell signalling mechanism, to enhance its ability to cause disease</html>[[Team:TUDelft/ReferencesBandAid|[1]]]. | ||
Revision as of 09:00, 16 September 2013
Band Aid
The Band Aid Modeling is related to the final application of our project. Specifically, we are going to use a band aid in which E.coli will be added. By locating the band aid on the wound, the S.aureus should be detected and killed.
As, it is already known, S.aureus is a pathogenic bacterium that utilises quorum sensing (QS), a cell-to-cell signalling mechanism, to enhance its ability to cause disease[1].
The communication is succeeded through small peptides known as AIPs. We engineered the receiver part of S.aureus to E.coli in order to be able for the last to detect AIPs produced by S.aureus.
