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| - | {{Team:UFMG Brazil/ufmg_style}} | + | {{Team:UFMG Brazil/barra}} |
| - | <html>
| + | {{carlos_teste}} |
| | + | {{Cardbio_barra_home_modeling}} |
| | + | {{Cardbio_barra_modeling}} |
| | | | |
| - | <head>
| + | =In the lab= |
| - | <script type="text/x-mathjax-config">
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| - | MathJax.Hub.Config({
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| - | tex2jax:
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| - | {
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| - | inlineMath: [['$','$'],['\\(','\\)']]
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| - | }
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| - | });
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| - | </script>
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| - | <script type='text/javascript' src='http://cdn.mathjax.org/mathjax/latest/MathJax.js?config=TeX-AMS-MML_HTMLorMML'></script>
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| - | </head>
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| | | | |
| - | <body>
| + | Texto introdutorio. |
| - | This is the sketch of our modeling.<br>
| + | |
| - | We are going to use TMAO as a biomarker.
| + | |
| | | | |
| - | <div id="variables_description">
| + | {{Team:UFMG Brazil/sponsor}} |
| - | <p> $M$ is TMAO. </p>
| + | |
| - | <p> $T$ is TorT. </p>
| + | |
| - | <p> $TM$ is the complex of T and M. </p>
| + | |
| - | <p> $S$ is TorS. </p>
| + | |
| - | <p> $STM$ is the complex of S and TM. </p>
| + | |
| - | <p> $R$ is TorR. </p>
| + | |
| - | <p> $R^{ *}$ is TorR Phosophorilated. </p>
| + | |
| - | </div>
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| - | | + | |
| - | <p><h1> Reactions:</h1></p>
| + | |
| - | \[
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| - | | + | |
| - | \begin{aligned}
| + | |
| - | \\
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| - | M+T{{k_{1} \atop\displaystyle\longrightarrow} \atop {\displaystyle\longleftarrow \atop k_{-1}}}TM
| + | |
| - | \\
| + | |
| - | 2TM+S{{k_{2} \atop\displaystyle\longrightarrow} \atop {\displaystyle\longleftarrow \atop k_{-2}}}STM
| + | |
| - | \\
| + | |
| - | STM+R{{k_{3} \atop\displaystyle\longrightarrow} \atop {\displaystyle\longleftarrow \atop k_{-3}}} X {{k_{cat}\atop\longrightarrow} \atop {\quad \atop \quad }}R^{ *} + STM
| + | |
| - | \\
| + | |
| - | R^{ *} + P {{\displaystyle\longrightarrow} \atop {\displaystyle\longleftarrow}} PR^{ *}
| + | |
| - | \\
| + | |
| - | \begin{eqnarray}
| + | |
| - | \begin{cases}
| + | |
| - | {d M(t)\over d t}&=& -k_1 \cdot M\cdot T + k_{-1}\cdot TM\\\\
| + | |
| - | \\\\
| + | |
| - | {d T(t)\over d t}&=& -k_1 \cdot M\cdot T + k_{-1}\cdot TM\\\\
| + | |
| - | \\\\
| + | |
| - | {d TM(t)\over d t}&=& k_1 \cdot M\cdot T - k_{-1}\cdot TM - k_2\cdot TM^{2} \cdot S + k_{-2} \cdot STM\\\\
| + | |
| - | \\\\
| + | |
| - | {d S(t)\over d t}&=& -k_2 \cdot S\cdot TM^{2} - k_{-1}\cdot TM - k_2\cdot TM^{2} \cdot S + k_{-2} \cdot STM\\\\
| + | |
| - | \\\\
| + | |
| - | {d STM(t)\over d t}&=& k_2 \cdot TM^{2} \cdot S - k_{-2}\cdot STM \\\\
| + | |
| - | \\\\
| + | |
| - | {d R^{ *}(t)\over d t}&=& k_{cat}\cdot STM \over{k_m + STM}\\\\
| + | |
| - | \\\\
| + | |
| - | {d mRNA(t)\over d t}&=& {\alpha \cdot R^{ *^{\gamma}} \over{\beta + R^{ *^{\gamma}}}} - \mu \cdot mRNA\\\\
| + | |
| - | \\
| + | |
| - | \end{cases}
| + | |
| - | \end{eqnarray}
| + | |
| - | \\
| + | |
| - | \end{aligned}
| + | |
| - | \]
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| - | | + | |
| - | </div>
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| - | | + | |
| - | </html>
| + | |
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