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Revision as of 21:56, 27 September 2013
Characterization: Background
Synthetic biology is about to design and construct biological devices and systems for useful purpose, which usually involves standardized parts and devices. And we believe behavior descriptions of riboswitches and aptamers will be quite helpful for the future iGEM teams and synthetics biologists considering their high selectivity and affinity.
Our intended characteristics describing the behavior of the riboswitches consist of the followings:
Static Relationship, which is about to measure the transfer function, details the relation between device input(s) and output(s) and allows prediction of the equilibrium behavior of composed devices.
Dynamic Relationship, we believe it is of great importance to report the response time of the device since it will be of great necessity when working with other devices in overall system.
Input Compatibility, which is intended to describe the behavior of our riboswitches when induced by some substances having similar structure with their own inducers.
Reference Canton B, Labno A, Endy D. Refinement and standardization of synthetic biological parts and devices[J]. Nature biotechnology, 2008, 26(7): 787-793.
