Team:OUC-China

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You are provided with this team page template with which to start the iGEM season. You may choose to personalize it to fit your team but keep the same "look." Or you may choose to take your team wiki to a different level and design your own wiki.  You can find some examples <a href="https://2009.igem.org/Help:Template/Examples">HERE</a>.
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|You can write a background of your team here. Give us a background of your team, the members, etc. Or tell us more about something of your choosing.
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|[[Image:OUC-China_logo.png|200px|right|frame]]
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|-
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''Tell us more about your project.  Give us background.  Use this as the abstract of your project.  Be descriptive but concise (1-2 paragraphs)''
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|[[Image:OUC-China_team.png|right|frame|Your team picture]]
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|-
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|align="center"|[[Team:OUC-China | Team OUC-China]]
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|}
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<!--- The Mission, Experiments --->
 
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!align="center"|[[Team:OUC-China|Home]]
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!align="center"|[[Team:OUC-China/Team|Team]]
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!align="center"|[https://igem.org/Team.cgi?year=2013&team_name=OUC-China Official Team Profile]
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!align="center"|[[Team:OUC-China/Project|Project]]
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!align="center"|[[Team:OUC-China/Parts|Parts Submitted to the Registry]]
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!align="center"|[[Team:OUC-China/Modeling|Modeling]]
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!align="center"|[[Team:OUC-China/Notebook|Notebook]]
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!align="center"|[[Team:OUC-China/Safety|Safety]]
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!align="center"|[[Team:OUC-China/Attributions|Attributions]]
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    <a class="navbar-brand" href="https://2013.igem.org/Team:OUC-China">
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      <p>OUC-China IGEM 2013</p>
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    </a>
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  </div>
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    <div class="collapse navbar-collapse navbar-ex1-collapse">
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      <ul class="nav navbar-nav pull-right">
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      <li><a href="https://2013.igem.org/Team:OUC-China">Home</a></li>
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            <li class="dropdown" role="menu" aria-labelledby="dropdownMenu">
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              <a class="dropdown-toggle" data-toggle="dropdown" href="#">Project<b class="caret"></b></a>
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              <ul class="dropdown-menu">
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          <li role="presentation"><a role="menuitem" tabindex="-1" href="https://2013.igem.org/Team:OUC-China/Overview">Overview</a></li>
 +
                  <li role="presentation"><a role="menuitem" tabindex="-1" href="https://2013.igem.org/Team:OUC-China/Achievement">Achievement & judge criteria</a></li>
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                    <li class="dropdown-submenu">
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                      <a tabindex="-1" href="#">Intracellular compartment</a>
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                <ul class="dropdown-menu">
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                        <li><a tabindex="-1" href="https://2013.igem.org/Team:OUC-China/Review">Review</a></li>
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                        <li><a tabindex="-1" href="https://2013.igem.org/Team:OUC-China/Design">Design</a></li>
 +
              <li><a tabindex="-1" href="https://2013.igem.org/Team:OUC-China/Microfluidics">Microfluidics</a></li>
 +
              <li><a tabindex="-1" href="https://2013.igem.org/Team:OUC-China/Results">Results</a></li>
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                </ul>
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            </li>
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                  <a tabindex="-1" href="#">RNA guardian</a>
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                      <li><a tabindex="-1" href="https://2013.igem.org/Team:OUC-China/Introduction">Introduction</a></li>
 +
                      <li><a tabindex="-1" href="https://2013.igem.org/Team:OUC-China/RNA guardian/Design">Design</a></li>
 +
            <li><a tabindex="-1" href="https://2013.igem.org/Team:OUC-China/RNA guardian/Results">Result</a></li>
 +
            <li><a tabindex="-1" href="https://2013.igem.org/Team:OUC-China/Reference">Reference</a></li>
 +
            </ul>
 +
          </li>
 +
          <li role="presentation"><a role="menuitem" tabindex="-1" href="https://2013.igem.org/Team:OUC-China/Part description">Part description</a></li>
 +
          <li role="presentation"><a role="menuitem" tabindex="-1" href="https://2013.igem.org/Team:OUC-China/Future work">Future work</a></li>
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                </ul>
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            </li>
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            <li class="dropdown" role="menu" aria-labelledby="dropdownMenu">
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              <a class="dropdown-toggle" data-toggle="dropdown" href="#">Modeling<b class="caret"></b></a>
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                <ul class="dropdown-menu">
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                  <li role="presentation"><a role="menuitem" tabindex="-1" href="https://2013.igem.org/Team:OUC-China/Magnetic Analysis">Magnetic Analysis</a></li>
 +
                  <li role="presentation"><a role="menuitem" tabindex="-1" href="https://2013.igem.org/Team:OUC-China/Model in RNA guardian">Model in RNA guardian</a></li>
 +
                </ul>
 +
            </li>
 +
            <li><a  href="https://2013.igem.org/Team:OUC-China/Human Practice">Human Practice</a></li>
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      <li class="dropdown">
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              <a class="dropdown-toggle" data-toggle="dropdown" href="#">Team<b class="caret"></b></a>
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              <ul class="dropdown-menu" role="menu" aria-labelledby="dropdownMenu">
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                  <li role="presentation"><a role="menuitem" tabindex="-1" href="https://2013.igem.org/Team:OUC-China/Members">Members</a></li>
 +
                  <li role="presentation"><a role="menuitem" tabindex="-1" href="https://2013.igem.org/Team:OUC-China/Instructors">Instructors</a></li>
 +
                  <li role="presentation"><a role="menuitem" tabindex="-1" href="https://2013.igem.org/Team:OUC-China/Advisor">Advisor</a></li>
 +
          <li role="presentation"><a role="menuitem" tabindex="-1" href="https://2013.igem.org/Team:OUC-China/Lab">Lab</a></li>
 +
          <li role="presentation"><a role="menuitem" tabindex="-1" href="https://2013.igem.org/Team:OUC-China/Acknowledgement">Acknowledgement</a></li>
 +
        </ul>
 +
            </li>
 +
      <li class="dropdown"><a  href="https://2013.igem.org/Team:OUC-China/Safety">Safety</a></li>
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      <li class="dropdown">
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                <a class="dropdown-toggle" data-toggle="dropdown" href="#">Notebook<b class="caret"></b></a>
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                <ul id="menu2" class="dropdown-menu" role="menu" aria-labelledby="dropdownMenu">
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                  <li role="presentation"><a role="menuitem" tabindex="-1" href="https://2013.igem.org/Team:OUC-China/Lab note">Lab note</a></li>
 +
                  <li role="presentation"><a role="menuitem" tabindex="-1" href="https://2013.igem.org/Team:OUC-China/Protocol">Protocol</a></li>
 +
                </ul>
 +
            </li>
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    </ul>
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          <div class="inner">
 +
            <h1>WE DID IT !</h1>
 +
            <p>Constructing an Artificial Organelle（Intracellular Compartment） in <i>E.coli</i></p>
 +
            <a class="btn" href="https://2013.igem.org/Team:OUC-China/Results">learn the story behind this picture</a>
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        <li style="background-image: url('https://static.igem.org/mediawiki/2013/7/7d/Cluster.png');">
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          <div class="inner">
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            <h1>Compression of Metabolic Pathways</h1>
 +
            <p>Constructing an artificial cluster to build the compartment by operating fewer genes. </p>
 +
            <a class="btn" href="https://2013.igem.org/Team:OUC-China/Design">learn more</a>
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          </div>
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          <div class="inner" style="float:left;padding-left:30px;">
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            <h1>Microfluidic Chip Magnetism Detection</h1>
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            <p><br></p>
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            <a class="btn" href="https://2013.igem.org/Team:OUC-China/Microfluidics" style="color:#1abc9c;">learn more</a>
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            <h1>Factors Considered in RNA guardian</h1>
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            <p><br /></p>
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            <a class="btn" href="https://2013.igem.org/Team:OUC-China/RNA_guardian/Design">Learn more</a>
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      <h3><b>Features Of Our Project</b></h3><hr>
 +
        <li>
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          <b><span class="glyphicon glyphicon-ok-sign"></span> Artificial Organelle(Intracellular Compartment)</b>
 +
          <p>We designed an artificial prokaryotic membranous organelle which is capable of anchoring proteins, opening up new possibilities for intracellular biochemistry reactions.</p>
 +
          <a class="btn btn-info" href="https://2013.igem.org/Team:OUC-China/Results">Learn more</a>
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        </li>
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        <li>
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          <b><span class="glyphicon glyphicon-ok-sign"></span> RNA Guardian</b>
 +
          <p>We took advantage of the 3D structure of RNA, using ribosomes as a barrier to stabilize RNA.</p>
 +
          <a class="btn btn-info" href="https://2013.igem.org/Team:OUC-China/Instruction">Learn more</a>
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        </li>
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        <li>
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          <b><span class="glyphicon glyphicon-ok-sign"></span> Microfluidic</b>
 +
          <p>We used Microfluidic Technology to detect the magnetism of our magnetic bacteria, <i>Magnetospirillum Magneticum</i>.</p>
 +
          <a class="btn btn-info" href="https://2013.igem.org/Team:OUC-China/Microfluidics">Learn more</a>
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        </li>
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        <li>
 +
          <b><span class="glyphicon glyphicon-ok-sign"></span> Preserving <i>mam</i>AB genes</b>
 +
          <p>We preserved <i>Magnetospirillum Magneticum</i> AMB-1 <i>mam</i>AB genes in <i>E.coli</i>, prevented the genes lose when AMB-1 strain was cultured in high oxygen partial pressure environment.</p>
 +
          <a class="btn btn-info" href="https://2013.igem.org/Team:OUC-China/Design">Learn more</a>
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        <h3><b>Introduction</b></h3><hr>
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        <p>Putting biological resources into production has now become a hot topic since the development of technology and the draining of natural resources. For example, research about biofuel and biochemistry is now flourishing. But biological products have drawbacks of being inefficient and not broad-spectrum. Inspired by eukaryotic membranous organelles, we aim to construct a prokaryotic membranous organelle to realize division of work inside the cell and improve the efficiency of production.
 +
How could a membrane be constructed in a Prokaryote? The answer may lie in this species: <i>Magnetosprillum Magneticum</i>, which can form a natural intracellular membrane. But this bacteria is slow-growing and requires demanding culture conditions, so the purpose of our project is to reconstruct the magnetosome membrane in <i><i>E.coli</i></i>, creating better conditions for efficient biological production.</p>
 +
        <p style="text-align:center"><a class="btn btn-large btn-info" href="https://2013.igem.org/Team:OUC-China/Overview">Learn more</a></p>
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Latest revision as of 03:38, 28 September 2013

    Features Of Our Project

  • Artificial Organelle(Intracellular Compartment)

    We designed an artificial prokaryotic membranous organelle which is capable of anchoring proteins, opening up new possibilities for intracellular biochemistry reactions.

    Learn more
  • RNA Guardian

    We took advantage of the 3D structure of RNA, using ribosomes as a barrier to stabilize RNA.

    Learn more
  • Microfluidic

    We used Microfluidic Technology to detect the magnetism of our magnetic bacteria, Magnetospirillum Magneticum.

    Learn more
  • Preserving mamAB genes

    We preserved Magnetospirillum Magneticum AMB-1 mamAB genes in E.coli, prevented the genes lose when AMB-1 strain was cultured in high oxygen partial pressure environment.

    Learn more

Introduction

Putting biological resources into production has now become a hot topic since the development of technology and the draining of natural resources. For example, research about biofuel and biochemistry is now flourishing. But biological products have drawbacks of being inefficient and not broad-spectrum. Inspired by eukaryotic membranous organelles, we aim to construct a prokaryotic membranous organelle to realize division of work inside the cell and improve the efficiency of production. How could a membrane be constructed in a Prokaryote? The answer may lie in this species: Magnetosprillum Magneticum, which can form a natural intracellular membrane. But this bacteria is slow-growing and requires demanding culture conditions, so the purpose of our project is to reconstruct the magnetosome membrane in E.coli, creating better conditions for efficient biological production.

Learn more

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