Team:INSA Toulouse

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       <h1 class="h1project">Project</h1>
       <h1 class="h1project">Project</h1>
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       <p>One major goal of Synthetic Biology is the transposition of electronic devices such as logic gates into genetic modules capables of circuit decisions. Recently (<a href="http://www.ncbi.nlm.nih.gov/pubmed/23396014" style="color: #5a6060">Siuti and al. 2013</a>, <a href="http://www.sciencemag.org/content/340/6132/599.abstract" style="color: #5a6060">Bonnet and al. 2013</a>), highly original logical gates utilizing Serine recombinases were described, avoiding reversibility of the genetic switch and thus creating strong and robust genetic logical gates (AND, XOR, OR).  
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       <p>One major goal of Synthetic Biology is the transposition of electronic devices such as logic gates into genetic modules capables of complex, autonomous decisions. Very recent publications described highly original logic gates utilizing serine recombinases, avoiding reversibility of the genetic switch and thus creating strong and robust genetic logical gates (AND, XOR, OR). <br> The <i>E. calculus</i> project exemplifies these genetic modules by creating a binary full-adder using AND and XOR gates. Our envisionned design could theoritically perform n-bits counting with a carry. Our project also aimed at validating original properties of these new genetic switches: irreversibility and accurate genetic transmission of the logic gate switched state to the cell'offspring.</p>
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The <i>E. calculus</i> project exemplifies these genetic modules by creating a n-bits full-adder using the AND and XOR gates. The proposed design could perform a n bits counting with a carry. Our project could validate some of the original properties of these new genetic switches: irreversibility and accurate genetic transmission to the offspring</p>
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<div class="buttoncadre1"> <a href="https://2013.igem.org/Team:INSA_Toulouse/contenu/project/overview" style="color:grey;"><p> VIEW MORE</p></a>
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              <div class="imgnew"><a href="https://2013.igem.org/Team:INSA_Toulouse/contenu/extras/achievements"><img style="width:70px;" src="https://static.igem.org/mediawiki/2013/a/a8/Three-olympic-medals.png"/></a></div>
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              <div class="textnew"><a href="https://2013.igem.org/Team:INSA_Toulouse/contenu/extras/achievements" style="color:grey;"><p>Check out our ACHIEVEMENTS page!! Watch out for this!!</p></a></div>
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               <div class="imgnew"><a href="https://2013.igem.org/Team:INSA_Toulouse/contenu/lab_practice/results"><img style="width:70px;" src="https://static.igem.org/mediawiki/2013/7/72/Test_carac.jpg"/></a></div>
               <div class="textnew"><a href="https://2013.igem.org/Team:INSA_Toulouse/contenu/lab_practice/results" style="color:grey;"><p>AND1 and XOR1 gates switched!!!!</p></a></div>
               <div class="textnew"><a href="https://2013.igem.org/Team:INSA_Toulouse/contenu/lab_practice/results" style="color:grey;"><p>AND1 and XOR1 gates switched!!!!</p></a></div>
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Latest revision as of 01:53, 5 October 2013

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Project

One major goal of Synthetic Biology is the transposition of electronic devices such as logic gates into genetic modules capables of complex, autonomous decisions. Very recent publications described highly original logic gates utilizing serine recombinases, avoiding reversibility of the genetic switch and thus creating strong and robust genetic logical gates (AND, XOR, OR).
The E. calculus project exemplifies these genetic modules by creating a binary full-adder using AND and XOR gates. Our envisionned design could theoritically perform n-bits counting with a carry. Our project also aimed at validating original properties of these new genetic switches: irreversibility and accurate genetic transmission of the logic gate switched state to the cell'offspring.