Team:Uppsala/test

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<title>Uppsala iGEM 2013</title>
<title>Uppsala iGEM 2013</title>
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<div id="igem_logo"><a href="https://2013.igem.org/Main_Page"><img class="igem_logo" src="https://static.igem.org/mediawiki/2013/5/59/IGEMlogo.png"></a></div>
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<div id="igem_logo"><a href="https://2013.igem.org/Team:Uppsala"><img class="igem_logo" src="https://static.igem.org/mediawiki/2013/e/e0/Uppsala2013_IGEMlogo.png"></a></div>
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<div id="igem"><a href="https://2013.igem.org/Main_Page"><img class="igem" src="https://static.igem.org/mediawiki/2013/b/b8/Uppsala2013_Uppsala_IGEM_log_blue.png"></a></div>
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<div id="cow-box"><a href="https://2013.igem.org/Team:Uppsala"><img class="home-knapp" src="https://static.igem.org/mediawiki/2013/9/9a/Home.png"><a/></div>
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<div id="cow-box"><a href="https://2013.igem.org/Team:Uppsala"><img class="home-knapp" src="https://static.igem.org/mediawiki/2013/e/ef/Uppsala2013_Home.png"><a/></div>
<ul>
<ul>
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<li><a href="https://2013.igem.org/Team:Uppsala/project" id="list_type1"><img class="nav-text" src="https://static.igem.org/mediawiki/2013/9/92/Project.png"></a>
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<li><a href="https://2013.igem.org/Team:Uppsala/project" id="list_type1"><img class="nav-text" src="https://static.igem.org/mediawiki/2013/a/aa/Uppsala2013_Project.png"></a>
<ul>
<ul>
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<li><a href="#">Result</a></li>
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<li><a href="https://2013.igem.org/Team:Uppsala/overview">Overiew</a></li>
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<li><a href="https://2013.igem.org/Team:Uppsala/chassi">Chassi</a>
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<li><a href="#">Chassi</a>
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<ul>
<ul>
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<li><a href="#">asd</a></li>
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                                                                <li><a href="https://2013.igem.org/Team:Uppsala/probiotics">Probiotics</a></li>
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<li><a href="#">asdad</a></li>
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<li><a href="https://2013.igem.org/Team:Uppsala/promoters">Promoters</a></li>
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<li><a href="#">bakasdla</a></li>
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<li><a href="https://2013.igem.org/Team:Uppsala/reporter-genes">Reporter genes</a></li>
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<li><a href="https://2013.igem.org/Team:Uppsala/toxin-antitoxin-system">Toxin-antitoxin system</a></li>
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<li><a href="https://2013.igem.org/Team:Uppsala/vectors">Vectors</a></li>
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                                                                <li><a href="https://2013.igem.org/Team:Uppsala/signal-peptide">Signal peptide</a></li>
</ul></li>
</ul></li>
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                                                <li><a href="https://2013.igem.org/Team:Uppsala/metabolic-engineering">Metabolic engineering</a>
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                                                    <ul>
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                                                                <li><a href="https://2013.igem.org/Team:Uppsala/p-coumaric-acid">P-coumaric acid</a></li>
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                                                                <li><a href="https://2013.igem.org/Team:Uppsala/resveratrol">Resveratrol</a></li>
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<li><a href="https://2013.igem.org/Team:Uppsala/lycopene">Lycopene</a></li>
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<li><a href="https://2013.igem.org/Team:Uppsala/betacarotene">β-carotene</a></li>
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                                                                <li><a
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href="https://2013.igem.org/Team:Uppsala/saffron">Saffron</a></li>
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<li><a href="https://2013.igem.org/Team:Uppsala/astaxanthin">Astaxanthin</a></li>
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<li><a href="https://2013.igem.org/Team:Uppsala/zeaxanthin">Zeaxanthin</a></li>
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</ul></li>
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</li>
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                                                <li><a
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href="https://2013.igem.org/Team:Uppsala/miraculin">Miraculin</a></li>
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<li><a href="https://2013.igem.org/Team:Uppsala/chromoproteins">Chromoproteins</a></li>
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<li><a href="https://2013.igem.org/Team:Uppsala/safety-experiment">Safety experiment</a></li>
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<li><a href="https://2013.igem.org/Team:Uppsala/results">Results</a></li>
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</ul></li>
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<li><a href="#">Chromoprotein collection</a></li>
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<li><a href="https://2013.igem.org/Team:Uppsala/modeling" id="list_type1"><img class="nav-text" src="https://static.igem.org/mediawiki/2013/6/63/Uppsala2013_Modeling.png"></a>
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<li><a href="#">Safety experiments</a></li>
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<li><a href="#">Resveratrol</a></li>
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<li><a href="#">Caretnoids</a></li>
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<li><a href="#">Saffron</a></li>
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<li><a href="#">Miraculin</a></li>
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<li><a href="https://2013.igem.org/Team:Uppsala/modeling" id="list_type1"><img class="nav-text" src="https://static.igem.org/mediawiki/2013/3/3c/Modeling.png"></a>
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<ul>
<ul>
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<li><a href="#">Resveratrol pathway </a></li>
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<li><a href="https://2013.igem.org/Team:Uppsala/P-Coumaric-acid-pathway">P-Coumaric acid</a></li>
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<li><a href="#">Carotenoids pathway </a></li>
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<li><a href="https://2013.igem.org/Team:Uppsala/modeling-tutorial">Modeling tutorial </a></li>
</ul></li>
</ul></li>
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<li><a href="https://2013.igem.org/Team:Uppsala/parts" id="list_type2"><img class="nav-text" src="https://static.igem.org/mediawiki/2013/7/79/Parts.png"></a></li>
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<li><a href="https://2013.igem.org/Team:Uppsala/parts" id="list_type2"><img class="nav-text" src="https://static.igem.org/mediawiki/2013/e/eb/Uppsala2013_parts.png"></a></li>
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<li><a href="https://2013.igem.org/Team:Uppsala/team" id="list_type2"><img class="nav-text" src="https://static.igem.org/mediawiki/2013/3/32/Team.png"></a>
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<li><a href="https://2013.igem.org/Team:Uppsala/team" id="list_type2"><img class="nav-text" src="https://static.igem.org/mediawiki/2013/a/a7/Uppsala2013_Team.png"></a>
<ul>
<ul>
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<li><a href="#">Resveratrol group</a></li>
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<li><a href="https://2013.igem.org/Team:Uppsala/resveratrol-group">Resveratrol group</a></li>
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<li><a href="#">Carotenoid group</a></li>
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<li><a href="https://2013.igem.org/Team:Uppsala/carotenoid-group">Carotenoid group</a></li>
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<li><a href="#">Chassi group</a></li>
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<li><a href="https://2013.igem.org/Team:Uppsala/chassi-group">Chassi group</a></li>
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<li><a href="#">Instructors & supervisors</a></li>
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                                                <li><a href="https://2013.igem.org/Team:Uppsala/advisors">Advisors</a></li>
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</ul></li>
</ul></li>
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<li><a href="https://2013.igem.org/Team:Uppsala/hp" id="list_type3"><img class="nav-text" src="https://static.igem.org/mediawiki/2013/f/f5/HP.png"></a>
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<li><a href="https://2013.igem.org/Team:Uppsala/human-practice" id="list_type3"><img class="nav-text"       src="https://static.igem.org/mediawiki/2013/b/b8/Uppsala2013_HP.png"></a>
<ul>
<ul>
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<li><a href="#">Yoghurt products</a></li>
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<li><a href="https://2013.igem.org/Team:Uppsala/yoghurt">Yoghurt +</a></li>
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<li><a href="https://2013.igem.org/Team:Uppsala/synbioday">Synbioday</a></li>
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<li><a href="https://2013.igem.org/Team:Uppsala/synbioday">SynBioDay</a></li>
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<li><a href="#">Bioethics</a></li>
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<li><a href="https://2013.igem.org/Team:Uppsala/biosafety-and-ethics">Biosafety and ethics</a></li>
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<li><a href="#">Safety</a></li>
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<li><a href="https://2013.igem.org/Team:Uppsala/public-opinion">Public opinion </a></li>
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<li><a href="#">Society / Public opinion</a></li>
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                                                <li><a href="https://2013.igem.org/Team:Uppsala/Outreach">High school & media </a></li>
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<li><a href="#">High School Outreach</a></li>
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<li><a href="https://2013.igem.org/Team:Uppsala/bioart">BioArt</a></li>
</ul></li>
</ul></li>
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<li><a href="https://2013.igem.org/Team:Uppsala/attribution" id="list_type4"><img class="nav-text" src="https://static.igem.org/mediawiki/2013/8/8d/Attributions.png"></a></li>  
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<li><a href="https://2013.igem.org/Team:Uppsala/attribution" id="list_type4"><img class="nav-text" src="https://static.igem.org/mediawiki/2013/5/5d/Uppsala2013_Attributions.png"></a></li>  
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<li><a href="https://2013.igem.org/Team:Uppsala/notebook" id="list_type3"><img class="nav-text" src="https://static.igem.org/mediawiki/2013/9/95/Notebook.png"></a></li>
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<li><a href="https://2013.igem.org/Team:Uppsala/notebook" id="list_type3"><img class="nav-text" src="https://static.igem.org/mediawiki/2013/3/36/Uppsala2013_Notebook.png"></a>
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                                    <ul>
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                                        <li><a href="https://2013.igem.org/Team:Uppsala/safety-form">Safety form</a></li>
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                                        <li><a href="https://2013.igem.org/Team:Uppsala/protocols">Protocols</a></li>
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                                    </ul></li>
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<div id="project-description">
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Making the world healthier with a new probiotic platform
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<p class="project-text"> Malnutrition is today a major global problem that affects people both in affluent and developing countries. Even if you get the right amount of calories, if these do not contain sufficient amounts of micronutrients, like vitamins and minerals, serious illness and even death can be the result.
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The goal of our project is to alleviate this problem by applying synthetic biology to <a href="https://2013.igem.org/Team:Uppsala/probiotics">probiotic bacteria</a>. These bacteria are already a part of normal human diet and our goal is to modify them so that they enrich the nutritional content of the food they grow in.<br><br>
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 +
With our project, we will make the lactobacillus genus the <a href="https://2013.igem.org/Team:Uppsala/chassi"> new probiotic platform </a> for <a href="https://2013.igem.org/Team:Uppsala/metabolic-engineering"> metabolic engineering </a> of nutritional compounds. We will engineer probiotics to produce beta-carotene (provitamin), resveratrol (antioxidant), miraculin (sweetener) and saffron (taste).
 +
 
 +
To exemplify what this combination of probiotics and metabolic engineering can accomplish we hope to use our modified bacteria to create nutritionally enriched yoghurt. We have also put great effort into addressing the <a href="https://2013.igem.org/Team:Uppsala/biosafety-and-ethics"> ethical and safety </a> issues that naturally follow when creating genetically modified food. As a part of this we organised a large event, <a href="https://2013.igem.org/Team:Uppsala/synbioday"> Uppsala SynBioDay </a>, with over 200 participants where these issues were discussed.
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                </div>
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</p>
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<div style="background-image:url('https://static.igem.org/mediawiki/2013/6/6c/Uppsala_cow_Upprop.png') o-repeat fixed center; background-size: 80% 80%; width: 100%; height: 200px;" ">
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<img src="" style="width:80%;">
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      <div style="z-index: 1000;width: 300px; height: 50px; position: relative; top: 500x; left: 500px; border: 1px solid black;"><a href="" style="width: 100%; height: 100%;"></a></div>
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<div id="grid-matrix">
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<div id="grid-a">
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  <a href="https://2013.igem.org/Team:Uppsala/project#project-anchor"><img class="top" src="https://static.igem.org/mediawiki/2013/a/a3/Uppsala2013_Background_new.png"></a>
</div>
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<div id="pic">
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bild
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                        <a href="https://2013.igem.org/Team:Uppsala/project#vision-anchor"><img class="top" src="https://static.igem.org/mediawiki/2013/1/13/Uppsala2013_Vision.png"></a>
</div>
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<div id="bactocontent">
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<div id="grid-c">
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<div id="resveratrol">
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                        <a href="https://2013.igem.org/Team:Uppsala/metabolic-engineering"><img class="top" src="https://static.igem.org/mediawiki/2013/4/4f/Uppsala2013_Metabolicengineering.png"></a>
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resveratrol
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<div id="p-com">
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p-com
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                        <a href="https://2013.igem.org/Team:Uppsala/chassi"><img class="top" src="https://static.igem.org/mediawiki/2013/1/19/Uppsala2013_Chassi.png"></a>
</div>
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<div id="grid-e">
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                        <a href="https://2013.igem.org/Team:Uppsala/human-practice"><img class="top" src="https://static.igem.org/mediawiki/2013/d/de/Uppsala2013_HumanPractice.png"></a>
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<div id="methods">
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methods
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<div id="grid-f">
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                        <a href="https://2013.igem.org/Team:Uppsala/results"><img class="top" src="https://static.igem.org/mediawiki/2013/a/a3/Uppsala2013_Achievements.png"></a>
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</div>
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<div id="sidebar">
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<div id="fb-feed">
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<iframe src="http://www.facebook.com/plugins/likebox.php?href=http://www.facebook.com/UppsalaIgem?fref=ts&width=292&colorscheme=light&show_fa
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ces=false&amp;border_color&amp;stream=true&amp;header=false&amp;height=475" scrolling="no" frameborder="0" style="border:none;
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overflow:hidden; width:310px; height:475px;" allowTransparency="true"></iframe>
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</div>
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<div id="twitter-feed">
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<a class="twitter-timeline" data-dnt="true" href="https://twitter.com/igemuppsala" data-widget-id="352909282024505345">Tweets av @igemuppsala</a>
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<script>!function(d,s,id){var js,fjs=d.getElementsByTagName(s)[0],p=/^http:/.test(d.location)?'http':'https';if(!d.getElementById(id)){js=d.createElement(s);js.id=id;js.src=p+"://platform.twitter.com/widgets.js";fjs.parentNode.insertBefore(js,fjs);}}(document,"script","twitter-wjs");</script>
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<img class="bottom-pic" src="https://static.igem.org/mediawiki/2013/a/aa/Bottom_picture.png">
 
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<div id="sponsor">
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<h1>Sponsors</h1>
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  <table class="sponsorTable">
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<tr class="colPush">
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<td class="centerThis"><img class="sponsors" src="https://static.igem.org/mediawiki/2013/a/a4/Uppsala_Clc.png"></td>
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<td><img class="sponsors" src="https://static.igem.org/mediawiki/2013/5/55/Uppsala_TekNat.png"></td><td><img class="sponsors" src="https://static.igem.org/mediawiki/2013/1/14/Uppsala_Analytik_Jena.png"></td></tr>
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<tr><td class="centerThis"><img class="sponsors" src="https://static.igem.org/mediawiki/2013/6/69/Uppsala_UU_logo.png"></td><td><img class="sponsors" src="https://static.igem.org/mediawiki/2013/9/9a/Uppsala_Microsynth.png"></td><td><img class="sponsors" src="https://static.igem.org/mediawiki/2013/b/ba/Vinnova.png"></td>
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</tr></table>
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</div>
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</div>
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<div id="bottom-pic">
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Latest revision as of 15:12, 27 October 2013

Making the world healthier with a new probiotic platform

Malnutrition is today a major global problem that affects people both in affluent and developing countries. Even if you get the right amount of calories, if these do not contain sufficient amounts of micronutrients, like vitamins and minerals, serious illness and even death can be the result. The goal of our project is to alleviate this problem by applying synthetic biology to probiotic bacteria. These bacteria are already a part of normal human diet and our goal is to modify them so that they enrich the nutritional content of the food they grow in.

With our project, we will make the lactobacillus genus the new probiotic platform for metabolic engineering of nutritional compounds. We will engineer probiotics to produce beta-carotene (provitamin), resveratrol (antioxidant), miraculin (sweetener) and saffron (taste). To exemplify what this combination of probiotics and metabolic engineering can accomplish we hope to use our modified bacteria to create nutritionally enriched yoghurt. We have also put great effort into addressing the ethical and safety issues that naturally follow when creating genetically modified food. As a part of this we organised a large event, Uppsala SynBioDay , with over 200 participants where these issues were discussed.