Team:ATOMS-Turkiye/Project/Module1

From 2013.igem.org

(Difference between revisions)

Revision as of 07:32, 17 May 2014

OVERVIEW

Cancer is the leading cause of death around the world. Tumor-targeted therapy is one of the major areas in cancer research.The rationale behind using targeted delivery is to facilitate or increase the effect of the delivered cargo to the targeted tissue and to reduce unwanted and non-specific effects of it in the surrounding area. Therefore, the first module of our project offers tracing cancer cells using antigen antibody interactions. We have designed a system in which a complex with antibodies attaches to cancer cells specifically and an enzyme system which triggers bacteria to move towards the cancer cells effectively. This complex is also used as a quorum sensing molecules to trigger bacterial response. The bacteria produce this complex which then results in the complex producing a quorum sensing molecule as a feed back mechanisms in the regions of cancer cells.

Below is a diagram of our description:

Reset

@@ Line 3: / Line 3: @@
 ==OVERVIEW==
-Cancer is the leading cause of death around the world. Tumor-targeted therapy is one of the major areas in cancer research.The rationale behind using targeted delivery is to facilitate or increase the effect of the delivered cargo to the targeted tissue and to reduce unwanted and non-specific effects of it in the surrounding area. Therefore, the first module of our project  offers tracing cancer cells using antigen antibody interactions. We have designed a system in which a complex with antibodies attaches to cancer cells specifically and an enzyme system which triggers bacteria to move towards the cancer cells effectively. This complex is also used for quorum sensing molecules to trigger bacterial response. Bacteria will produce this complex then, this complex produced quorum sensing molecule as a feed back at the presence of cancer cells.
+Cancer is the leading cause of death around the world. Tumor-targeted therapy is one of the major areas in cancer research.The rationale behind using targeted delivery is to facilitate or increase the effect of the delivered cargo to the targeted tissue and to reduce unwanted and non-specific effects of it in the surrounding area. Therefore, the first module of our project  offers tracing cancer cells using antigen antibody interactions. We have designed a system in which a complex with antibodies attaches to cancer cells specifically and an enzyme system which triggers bacteria to move towards the cancer cells effectively. This complex is also used as a quorum sensing molecules to trigger bacterial response. The bacteria produce this complex which then results in the complex producing a quorum sensing molecule as a feed back mechanisms in the regions of cancer cells.
+''Below is a diagram of our description:''
 {{:Team:ATOMS-Turkiye/Templates/Module1:Overview}}
 </div>